Urea

DRUG INFORMATION

  ADULT
    - Apply Urea 40% to affected skin twice per day, or as directed by your physician.
      Rub in until completely absorbed. Apply to diseased or damaged nail(s) twice per
      day, or as directed by a physician. All prescription substitutions and/or
      recommendations using this product shall be made subject to state and federal
      statutes as applicable.
      Source: US FDA label for urea (Urea Cream 40%), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - No child dose in this label. That usually means untested in children, not
      unsuitable - use a paediatric source.
      Source: Read and found silent: the US FDA label for urea (Urea Cream 40%),
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for urea (Urea Cream 40%),
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for urea (Urea Cream 40%),
      retrieved 2026-08-29

  PREGNANCY
    - Animal reproduction studies have revealed no evidence of harm to the fetus,
      however, there are no adequate and well-controlled studies in pregnant women.
      Source: US FDA label for urea (Urea Cream 40%), section 'pregnancy', retrieved
      2026-08-29
    - Because animal reproductive studies are not always predictive of human response,
      Urea 40% should be given to a pregnant woman only if clearly needed.
      Source: US FDA label for urea (Urea Cream 40%), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING   [ CAUTION ]
    The label allows it only when the benefit is judged to outweigh the risk. Read the
      quote below.
    - It is not known whether or not this drug is excreted in human milk.
      Source: US FDA label for urea (Urea Cream 40%), section 'nursing mothers',
      retrieved 2026-08-29
    - Because many drugs are excreted in human milk, caution should be exercised when
      Urea 40% is administered to a nursing woman.
      Source: US FDA label for urea (Urea Cream 40%), section 'nursing mothers',
      retrieved 2026-08-29