Thiamine

DRUG INFORMATION

  ADULT
    - In the treatment of beriberi, 10 mg to 20 mg of thiamine hydrochloride are given
      IM 3 times daily for as long as 2 weeks.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'dosage and
      administration', retrieved 2026-08-29
    - (See WARNINGS regarding repeated injection of thiamine.) An oral therapeutic
      multivitamin preparation containing 5 mg to 10 mg thiamine, administered daily for
      one month, is recommended to achieve body tissue saturation.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'dosage and
      administration', retrieved 2026-08-29
    - Patients with neuritis of pregnancy in whom vomiting is severe enough to preclude
      adequate oral therapy should receive 5 mg to 10 mg of thiamine hydrochloride IM
      daily.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - “Wet” beriberi with myocardial failure must be treated as an emergency cardiac
      condition, and thiamine must be administered slowly by the IV route in this
      situation (see WARNINGS ). In the treatment of beriberi, 10 mg to 20 mg of
      thiamine hydrochloride are given IM 3 times daily for as long as 2 weeks.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'dosage and
      administration', retrieved 2026-08-29
    - Infantile beriberi that is mild may respond to oral therapy, but if collapse
      occurs, doses of 25 mg may cautiously be given IV.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'dosage and
      administration', retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for thiamine (Thiamine
      Hydrochloride), retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for thiamine (Thiamine
      Hydrochloride), retrieved 2026-08-29

  PREGNANCY   [ CAUTION ]
    The label allows it only when the benefit is judged to outweigh the risk. Read the
      quote below.
    - Usage in Pregnancy Studies in pregnant women have not shown that thiamine
      hydrochloride increases the risk of fetal abnormalities if administered during
      pregnancy.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'pregnancy',
      retrieved 2026-08-29
    - If the drug is used during pregnancy, the possibility of fetal harm appears
      remote.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'pregnancy',
      retrieved 2026-08-29
    - Because studies cannot rule out the possibility of harm however, thiamine
      hydrochloride should be used during pregnancy only if clearly needed.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'pregnancy',
      retrieved 2026-08-29

  BREASTFEEDING   [ CAUTION ]
    The label allows it only when the benefit is judged to outweigh the risk. Read the
      quote below.
    - It is not known whether this drug is excreted in human milk.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'nursing
      mothers', retrieved 2026-08-29
    - Because many drugs are excreted in human milk, caution should be exercised when
      thiamine hydrochloride is administered to a nursing mother.
      Source: US FDA label for thiamine (Thiamine Hydrochloride), section 'nursing
      mothers', retrieved 2026-08-29