Streptomycin

DRUG INFORMATION

  ADULT
    - When streptomycin is added to this regimen because of suspected or proven drug
      resistance (see INDICATIONS AND USAGE section), the recommended dosing for
      streptomycin is as follows: Daily Twice Weekly Thrice Weekly Children 20-40 mg/kg
      Max 1 g 25-30 mg/kg Max 1.5 g 25-30 mg/kg Max 1.5 g Adults 15 mg/kg Max 1 g 25-30
      mg/kg Max 1.5 g 25-30 mg/kg Max 1.5 g Streptomycin is usually administered daily
      as a single intramuscular injection.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29
    - A total dose of not more than 120 g over the course of therapy should be given
      unless there are no other therapeutic options.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29
    - TULAREMIA: 1 to 2 g daily in divided doses for 7 to 14 days until the patient is
      afebrile for 5 to 7 days. 3.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29

  CHILD
    - Intramuscular Route Only Adults: The preferred site is the upper outer quadrant of
      the buttock (i.e., gluteus maximus) or the mid-lateral thigh. Children: It is
      recommended that intramuscular injections be given preferably in the mid-lateral
      muscles of the thigh.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29
    - When streptomycin is added to this regimen because of suspected or proven drug
      resistance (see INDICATIONS AND USAGE section), the recommended dosing for
      streptomycin is as follows: Daily Twice Weekly Thrice Weekly Children 20-40 mg/kg
      Max 1 g 25-30 mg/kg Max 1.5 g 25-30 mg/kg Max 1.5 g Adults 15 mg/kg Max 1 g 25-30
      mg/kg Max 1.5 g 25-30 mg/kg Max 1.5 g Streptomycin is usually administered daily
      as a single intramuscular injection.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29
    - For children: 20 to 40 mg/kg/day (8 to 20 mg/lb/day) in divided doses every 6 to
      12 hours.
      Source: US FDA label for streptomycin (Streptomycin), section 'dosage and
      administration', retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for streptomycin (Streptomycin),
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for streptomycin (Streptomycin),
      retrieved 2026-08-29

  PREGNANCY
    - Nothing on pregnancy in this label. Treat as unknown, not as safe.
      Source: Read and found silent: the US FDA label for streptomycin (Streptomycin),
      retrieved 2026-08-29

  BREASTFEEDING
    - Because of the potential for serious adverse reactions in nursing infants from
      streptomycin, a decision should be made whether to discontinue nursing or to
      discontinue the drug, taking into account the importance of the drug to the
      mother.
      Source: US FDA label for streptomycin (Streptomycin), section 'nursing mothers',
      retrieved 2026-08-29