{
  "schema_version": 1,
  "kind": "drug_profile",
  "generic": "potassium chloride",
  "review_status": "reviewed",
  "origin": "openfda",
  "sections": {
    "adult": [
      {
        "text": "Monitor serum potassium and adjust dosages accordingly (2.1) If serum potassium is less than 2.5 mEq/L, use intravenous potassium instead of oral supplementation (2.1) Take with meals and with a glass of water or other liquid. Swallow tablets whole without crushing, chewing or sucking. (2.1) Treatment of hypokalemia: Doses range from 40-100 mEq/day in divided doses. Limit doses to 40 mEq per dose.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'dosage and administration', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      }
    ],
    "child": [
      {
        "text": "Safety and effectiveness in the pediatric population have not been established.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'pediatric use', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      }
    ],
    "renal": [
      {
        "text": "Cirrhosis: Initiate therapy at the low end of the dosing range (8.6) Renal Impairment: Initiate therapy at the low end of the dosing range (8.7) 8.1 Pregnancy Risk Summary There are no human data related to use of Potassium Chloride Extended-release Tablets, USP during pregnancy, and animal reproduction studies have not been conducted.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'use in specific populations', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      },
      {
        "text": "Patients with cirrhosis should usually be started at the low end of the dosing range, and the serum potassium level should be monitored frequently [see Clinical Pharmacology (12.3) ]. 8.7 Renal Impairment Patients with renal impairment have reduced urinary excretion of potassium and are at substantially increased risk of hyperkalemia [see Warnings and Precautions (5.2)] .",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'use in specific populations', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      }
    ],
    "hepatic": [
      {
        "text": "No liver-impairment dose in this label. Not a statement that none is needed.",
        "source": "Read and found silent: the US FDA label for potassium chloride (Potassium Chloride), retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": false
      }
    ],
    "pregnancy": [
      {
        "text": "Risk Summary There are no human data related to use of Potassium Chloride Extended-release Tablets, USP during pregnancy, and animal reproduction studies have not been conducted.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      },
      {
        "text": "Potassium supplementation that does not lead to hyperkalemia is not expected to cause fetal harm.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      },
      {
        "text": "The background risk for major birth defects and miscarriage in the indicated population is unknown.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'pregnancy', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      }
    ],
    "lactation": [
      {
        "text": "Risk Summary The normal potassium ion content of human milk is about 13 mEq per liter.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      },
      {
        "text": "Since oral potassium becomes part of the body potassium pool, so long as body potassium is not excessive, the contribution of potassium chloride supplementation should have little or no effect on the level in human milk.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'nursing mothers', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      },
      {
        "text": "In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively. 8.2 Lactation Risk Summary The normal potassium ion content of human milk is about 13 mEq per liter.",
        "source": "US FDA label for potassium chloride (Potassium Chloride), section 'use in specific populations', retrieved 2026-08-29",
        "cached_file": "labels/potassium-chloride.json",
        "verbatim": true
      }
    ]
  }
}