Pilocarpine

DRUG INFORMATION

  ADULT
    - Instill one drop in the eye(s) up to four times daily. (2) 2.1 Reduction of
      Elevated Intraocular Pressure (IOP) in Patients with Open-Angle Glaucoma or Ocular
      Hypertension One drop of pilocarpine hydrochloride ophthalmic solution 1%, 2% or
      4% should be applied topically in the eye(s) up to four times daily. Pilocarpine-
      naïve patients should be started on the 1% concentration as higher concentrations
      are often not tolerated initially.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section 'dosage
      and administration', retrieved 2026-08-29

  CHILD
    - Safety and effectiveness of pilocarpine hydrochloride ophthalmic solution in
      pediatric patients have been established.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section
      'pediatric use', retrieved 2026-08-29
    - Instill one drop in the eye(s) up to four times daily. (2) 2.1 Reduction of
      Elevated Intraocular Pressure (IOP) in Patients with Open-Angle Glaucoma or Ocular
      Hypertension One drop of pilocarpine hydrochloride ophthalmic solution 1%, 2% or
      4% should be applied topically in the eye(s) up to four times daily. Pilocarpine-
      naïve patients should be started on the 1% concentration as higher concentrations
      are often not tolerated initially.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section 'dosage
      and administration', retrieved 2026-08-29

  RENAL IMPAIRMENT
    - No kidney-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for pilocarpine (Pilocarpine
      Hydrochloride), retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for pilocarpine (Pilocarpine
      Hydrochloride), retrieved 2026-08-29

  PREGNANCY
    - Animal reproduction studies have not been conducted with pilocarpine
      hydrochloride.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section
      'pregnancy', retrieved 2026-08-29
    - It is also not known whether pilocarpine hydrochloride can cause fetal harm when
      administered to a pregnant woman or can affect reproduction capacity.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section
      'pregnancy', retrieved 2026-08-29
    - Pilocarpine hydrochloride ophthalmic solution should be given to a pregnant woman
      only if clearly needed.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section
      'pregnancy', retrieved 2026-08-29

  BREASTFEEDING
    - It is not known whether this drug is excreted in human milk.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section 'nursing
      mothers', retrieved 2026-08-29
    - Because many drugs are excreted in human milk, caution should be exercised when
      pilocarpine hydrochloride ophthalmic solution is administered to a nursing woman.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section 'nursing
      mothers', retrieved 2026-08-29
    - Pilocarpine hydrochloride ophthalmic solution should be given to a pregnant woman
      only if clearly needed. 8.3 Nursing Mothers It is not known whether this drug is
      excreted in human milk.
      Source: US FDA label for pilocarpine (Pilocarpine Hydrochloride), section 'use in
      specific populations', retrieved 2026-08-29