Drug profile
Phenoxymethyl Penicillin
Adult, child, renal, hepatic, pregnancy and breastfeeding information, with the source named on every line.
DRUG INFORMATION
ADULT
- The usual dosage recommendations for adults and children 12 years and over are as
follows: Streptococcal infections —mild to moderately severe—of the upper
respiratory tract and including scarlet fever and erysipelas: 125 to 250 mg
(200,000 to 400,000 units) every 6 to 8 hours for 10 days.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
- Pneumococcal infections —mild to moderately severe—of the respiratory tract,
including otitis media: 250 to 500 mg (400,000 to 800,000 units) every 6 hours
until the patient has been afebrile for at least 2 days.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
- Staphylococcal infections —mild infections of skin and soft tissue (culture and
sensitivity tests should be performed): 250 to 500 mg (400,000 to 800,000 units)
every 6 to 8 hours.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
CHILD
- The dosage of penicillin V potassium tablets and penicillin V potassium for oral
solution should be determined according to the sensitivity of the causative
microorganisms and the severity of infection, and adjusted to the clinical
response of the patient.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
- The usual dosage recommendations for adults and children 12 years and over are as
follows: Streptococcal infections —mild to moderately severe—of the upper
respiratory tract and including scarlet fever and erysipelas: 125 to 250 mg
(200,000 to 400,000 units) every 6 to 8 hours for 10 days.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
- For prophylaxis against bacterial endocarditis 1 in patients with congenital heart
disease or rheumatic or other acquired valvular heart disease when undergoing
dental procedures or surgical procedures of the upper respiratory tract: 2 gram of
penicillin V (1 gram for children under 60 lbs.) 1 hour before the procedure, and
then, 1 gram (500 mg for children under 60 lbs.) 6 hours later.
Source: US FDA label for penicillin v potassium (Penicillin V Potassium), section
'dosage and administration', retrieved 2026-08-29
RENAL IMPAIRMENT
- No kidney-impairment dose in this label. Not a statement that none is needed.
Source: Read and found silent: the US FDA label for penicillin v potassium
(Penicillin V Potassium), retrieved 2026-08-29
HEPATIC IMPAIRMENT
- No liver-impairment dose in this label. Not a statement that none is needed.
Source: Read and found silent: the US FDA label for penicillin v potassium
(Penicillin V Potassium), retrieved 2026-08-29
PREGNANCY
- Nothing on pregnancy in this label. Treat as unknown, not as safe.
Source: Read and found silent: the US FDA label for penicillin v potassium
(Penicillin V Potassium), retrieved 2026-08-29
BREASTFEEDING
- Nothing on breastfeeding in this label. Treat as unknown, not as safe.
Source: Read and found silent: the US FDA label for penicillin v potassium
(Penicillin V Potassium), retrieved 2026-08-29