Cefdinir

DRUG INFORMATION

  ADULT
    - Patients With Renal Insufficiency For adult patients with creatinine clearance <
      30 mL/min, the dose of cefdinir should be 300 mg given once daily.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29
    - In patients maintained on chronic hemodialysis, the recommended initial dosage
      regimen is a 300 mg or 7 mg/kg dose every other day.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29
    - Subsequent doses (300 mg or 7 mg/kg) are then administered every other day.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29

  CHILD
    - Safety and efficacy in neonates and infants less than 6 months of age have not
      been established. Use of cefdinir for the treatment of acute maxillary sinusitis
      in pediatric patients (age 6 months through 12 years) is supported by evidence
      from adequate and well-controlled studies in adults and adolescents, the similar
      pathophysiology of acute sinusitis in adult and pediatric patients, and
      comparative pharmacokinetic data in the pediatric population.
      Source: US FDA label for cefdinir (Cefdinir), section 'pediatric use', retrieved
      2026-08-29
    - (See INDICATIONS AND USAGE for Indicated Pathogens.) Powder for Oral Suspension
      The recommended dosage and duration of treatment for infections in pediatric
      patients are described in the following chart; the total daily dose for all
      infections is 14 mg/kg, up to a maximum dose of 600 mg per day. Once-daily dosing
      for 10 days is as effective as BID dosing.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29
    - (See INDICATIONS AND USAGE for Indicated Pathogens.) Powder for Oral Suspension
      The recommended dosage and duration of treatment for infections in pediatric
      patients are described in the following chart; the total daily dose for all
      infections is 14 mg/kg, up to a maximum dose of 600 mg per day.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29

  RENAL IMPAIRMENT
    - Patients With Renal Insufficiency For adult patients with creatinine clearance <
      30 mL/min, the dose of cefdinir should be 300 mg given once daily.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29
    - Creatinine clearance is difficult to measure in outpatients.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29
    - However, the following formula may be used to estimate creatinine clearance (CL cr
      ) in adult patients.
      Source: US FDA label for cefdinir (Cefdinir), section 'dosage and administration',
      retrieved 2026-08-29

  HEPATIC IMPAIRMENT
    - No liver-impairment dose in this label. Not a statement that none is needed.
      Source: Read and found silent: the US FDA label for cefdinir (Cefdinir), retrieved
      2026-08-29

  PREGNANCY
    - Teratogenic Effects Cefdinir was not teratogenic in rats at oral doses up to 1000
      mg/kg/day (70 times the human dose based on mg/kg/day, 11 times based on mg/m 2
      /day) or in rabbits at oral doses up to 10 mg/kg/day (0.7 times the human dose
      based on mg/kg/day, 0.23 times based on mg/m 2 /day).
      Source: US FDA label for cefdinir (Cefdinir), section 'pregnancy', retrieved
      2026-08-29
    - Maternal toxicity (decreased body weight gain) was observed in rabbits at the
      maximum tolerated dose of 10 mg/kg/day without adverse effects on offspring.
      Source: US FDA label for cefdinir (Cefdinir), section 'pregnancy', retrieved
      2026-08-29
    - Decreased body weight occurred in rat fetuses at ≥ 100 mg/kg/day, and in rat
      offspring at ≥ 32 mg/kg/day.
      Source: US FDA label for cefdinir (Cefdinir), section 'pregnancy', retrieved
      2026-08-29

  BREASTFEEDING
    - Following administration of single 600 mg doses, cefdinir was not detected in
      human breast milk.
      Source: US FDA label for cefdinir (Cefdinir), section 'nursing mothers', retrieved
      2026-08-29