# Yellow Fever - Category: chronic - Review status: reviewed (every claim checked against a document named on this page) - Sources: ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD14.07 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care · Yellow Fever - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK470425/ - Verified date: 2026-08 ## Verified against - No dose - referral pathway, no medicine given in primary care - MSF Essential Drugs 2024 - Yellow Fever - disease-level clinical article (yellow-fever-clinical.txt) ## Treatment metadata - No drug therapy in primary care (Recognition & Referral) - Yellow fever vaccine — injection ## Complete treatment card ```text YELLOW FEVER Sources: ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD14.07 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care · Yellow Fever - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK470425/ Review status: REVIEWED against No dose - referral pathway, no medicine given in primary care, MSF Essential Drugs 2024, Yellow Fever - disease-level clinical article (yellow-fever-clinical.txt) (2026-08) IS IT THIS? - reference only, to read alongside your own examination SYMPTOMS - what the patient reports (3) - Headache, malaise, jaundice, and severe back pain are commonly reported [back pain · headache · jaundice · malaise] - About 15 percent go on to severe illness with chills, low back pain, headache, and fever [back pain · chills · fever · headache] - A symptom-free remission lasting 24 to 48 hours can be followed by return of symptoms and marked toxicity SIGNS - what you find (2) - Fever with a relatively slow pulse (Faget sign), facial flushing, and red eyes [bradycardia · fever] - In the toxic phase: jaundice, dark urine, vomiting, and bleeding from mucous membranes or the gut [bleeding · jaundice · vomiting] TESTS (5) - Antigen immunoassay or PCR for viral genome gives rapid confirmation - ELISA and antibody titers can also establish the diagnosis - Blood work often shows a low white count with raised liver enzymes; neutropenia is common in the first week - Rising creatinine, low blood sugar, and metabolic acidosis strongly signal a poor prognosis - ECG can show a prolonged QT and PR interval, and arrhythmias when the heart muscle is affected IF NOT THIS - what else fits (6) - Other viral hemorrhagic fevers are on the differential - Viral hepatitis can present similarly - Malaria is an important mimic to exclude, especially with a relevant travel history - Typhoid fever is on the differential list - Dengue fever can present similarly - Leptospirosis is also considered in the differential Source StatPearls "Yellow Fever" - disease-level clinical article Status traced to the source above 1. NO DRUG THERAPY IN PRIMARY CARE (RECOGNITION & REFERRAL)[1st line] Adult Mosquito-borne viral haemorrhagic fever endemic to parts of Africa and South America, not Egypt. In practice the primary-care task connected to this code is travel medicine - Egypt requires proof of yellow fever vaccination from travellers arriving from endemic countries - rather than treating the disease itself. - Refer Peds Children follow the same pathway: recognise and refer. No primary-care medicine is implied. Source No dose - referral pathway, no medicine given in primary care Why Mosquito-borne viral haemorrhagic fever endemic to parts of Africa and South America, not Egypt. In practice the primary-care task connected to this code is travel medicine - Egypt requires proof of yellow fever vaccination from travellers arriving from endemic countries - rather than treating the disease itself. Caution Not endemic in Egypt. Relevant to a returning traveller or an imported case; consider the travel history before anything else. No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to. RED FLAG - The toxic phase progresses with DIC, hemorrhage, renal failure, and hepatic failure (ICU admission, 30-50% mortality). RED FLAG - Fever with jaundice or bleeding after travel to an endemic country needs urgent referral; do not manage it as a routine viral fever. A traveller lacking a valid yellow fever vaccination certificate when required is a travel-clinic or administrative issue, not a clinical one. 2. YELLOW FEVER VACCINE [2nd line] Adult 0.5 ml single dose Peds Child >= 9 months: 0.5 ml single dose by IM injection (contraindicated in children < 6 months). Source MSF Essential Drugs 2024 Why Live-attenuated vaccine conferring lifelong immunity for pre-travel prophylaxis against yellow fever. Caution Contraindicated in egg allergy, immunocompromised patients, symptomatic HIV infection, or immunosuppressive treatment. Contraindicated in infants less than 6 months of age. Egypt STAMARIL VACCINE SANOFI PASTEU... 50.00 EGP Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy. ``` --- Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement. [Privacy policy](/privacy)