Dawaa Reference

Clinical reference

Yellow Fever

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources3 sources

ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AD14.07 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care · Yellow Fever - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK470425/

Verified against3 documents
  • No dose - referral pathway, no medicine given in primary care
  • MSF Essential Drugs 2024
  • Yellow Fever - disease-level clinical article (yellow-fever-clinical.txt)

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Symptoms — what the patient reports (3)

  • Headache, malaise, jaundice, and severe back pain are commonly reported [back pain · headache · jaundice · malaise]
  • About 15 percent go on to severe illness with chills, low back pain, headache, and fever [back pain · chills · fever · headache]
  • A symptom-free remission lasting 24 to 48 hours can be followed by return of symptoms and marked toxicity

Signs — what you find (2)

  • Fever with a relatively slow pulse (Faget sign), facial flushing, and red eyes [bradycardia · fever]
  • In the toxic phase: jaundice, dark urine, vomiting, and bleeding from mucous membranes or the gut [bleeding · jaundice · vomiting]

Tests (5)

  • Antigen immunoassay or PCR for viral genome gives rapid confirmation
  • ELISA and antibody titers can also establish the diagnosis
  • Blood work often shows a low white count with raised liver enzymes; neutropenia is common in the first week
  • Rising creatinine, low blood sugar, and metabolic acidosis strongly signal a poor prognosis
  • ECG can show a prolonged QT and PR interval, and arrhythmias when the heart muscle is affected

If not this — what else fits (6)

  • Other viral hemorrhagic fevers are on the differential
  • Viral hepatitis can present similarly
  • Malaria is an important mimic to exclude, especially with a relevant travel history
  • Typhoid fever is on the differential list
  • Dengue fever can present similarly
  • Leptospirosis is also considered in the differential

SourceStatPearls "Yellow Fever" - disease-level clinical article

Presentation findings are traced to the source above.

1

NO DRUG THERAPY IN PRIMARY CARE (RECOGNITION & REFERRAL)

1st line
Adult dose and duration

Mosquito-borne viral haemorrhagic fever endemic to parts of Africa and South America, not Egypt. In practice the primary-care task connected to this code is travel medicine - Egypt requires proof of yellow fever vaccination from travellers arriving from endemic countries - rather than treating the disease itself. - Refer

Paediatric dose

Children follow the same pathway: recognise and refer. No primary-care medicine is implied.

Dose source

No dose - referral pathway, no medicine given in primary care

Why

Mosquito-borne viral haemorrhagic fever endemic to parts of Africa and South America, not Egypt. In practice the primary-care task connected to this code is travel medicine - Egypt requires proof of yellow fever vaccination from travellers arriving from endemic countries - rather than treating the disease itself.

Cautions
  • Not endemic in Egypt. Relevant to a returning traveller or an imported case; consider the travel history before anything else.
  • No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.
  • RED FLAG - The toxic phase progresses with DIC, hemorrhage, renal failure, and hepatic failure (ICU admission, 30-50% mortality).
  • RED FLAG - Fever with jaundice or bleeding after travel to an endemic country needs urgent referral; do not manage it as a routine viral fever.
  • A traveller lacking a valid yellow fever vaccination certificate when required is a travel-clinic or administrative issue, not a clinical one.
2

YELLOW FEVER VACCINE

2nd line

Forminjection

Adult dose and duration

0.5 ml single dose

Paediatric dose
Dose by age
Child >= 9 months:0.5 ml single dose by IM injection (contraindicated in children < 6 months).
Dose source

MSF Essential Drugs 2024

Why

Live-attenuated vaccine conferring lifelong immunity for pre-travel prophylaxis against yellow fever.

Cautions
  • Contraindicated in egg allergy, immunocompromised patients, symptomatic HIV infection, or immunosuppressive treatment.
  • Contraindicated in infants less than 6 months of age.
Egyptian brands
Egyptian brandManufacturerIndicative price
STAMARIL VACCINESANOFI PASTEUR-FRANCE > ETIMEX-EGYPT50.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.