Dawaa Reference

Clinical reference

Watery eye (epiphora)

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources4 sources

ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class FS03.00 - condition scope only, no dose · Nasolacrimal Duct Obstruction - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK532873/ · Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) · Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.

Verified against3 documents
  • Watery eye (epiphora) - disease-level clinical article (watery-eye-full.txt)
  • Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931)
  • Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Symptoms — what the patient reports (11)

  • Sudden-onset tearing usually points to a local cause [eye discharge]
  • Gradually worsening tearing suggests narrowing of the nasolacrimal duct [eye discharge · stricture]
  • Watering plus discomfort right after waking can point to a recurring corneal erosion
  • A painful, one-sided watery eye raises concern for a foreign body, corneal ulcer or abrasion, keratitis, glaucoma, or iritis [foreign body]
  • Itching suggests an allergy, sometimes triggered by eye drops such as glaucoma medication [itching]
  • Burning and discomfort on blinking that is worse in the morning suggests dry eye [dry eye]
  • Purulent discharge points to bacterial infection, while bloody discharge raises concern for a lacrimal sac tumor [eye discharge · pus]
  • Tearing that occurs with eating, chewing, or talking suggests aberrant regeneration of the facial nerve (crocodile tears) [eye discharge]
  • Certain eye drops, including pilocarpine, phospholine iodide, and idoxuridine, can cause tear-duct obstruction
  • Prior radiation to the eye area for skin cancer can scar the punctum or canaliculus [scarring]
  • The overflow itself causes blurred vision, and discharge when the lacrimal sac is infected or a foreign body sits in the canaliculus [blurred vision · eye discharge · foreign body]

Signs — what you find (11)

  • Brow droop, upper-lid retraction, or eye closure when chewing points to old facial nerve palsy with aberrant regeneration [cranial nerve palsy]
  • A mass above the medial canthal tendon suggests an ethmoid lesion, while one below it suggests a lacrimal sac problem
  • Redness and tenderness over the lacrimal sac points to dacryocystitis [redness]
  • Mucoid discharge expressed from the puncta on pressing the lacrimal sac indicates a mucocele [eye discharge]
  • A firm, non-fluctuant mass over the sac raises concern for a lacrimal sac tumor
  • A lower lid that fails to snap back promptly after traction points to orbicularis weakness or lax canthal tendons
  • Fluorescein staining high on the cornea suggests a foreign body lodged under the upper eyelid [foreign body]
  • Punctate corneal staining can be seen with trichiasis
  • An upper lid that everts easily with upward pressure and shows a follicular reaction suggests floppy eyelid syndrome
  • The globe moving with the lower lid on downward traction, or conjunctival bands, indicates symblepharon
  • Constant wiping excoriates the eyelid skin and leaves the lower lids lax

Tests (9)

  • A dacryocystogram confirms true patency of the tear drainage system when the diagnosis is unclear
  • If irrigation shows patency but tearing continues, dacryocystography can still reveal an underlying narrowing
  • Fluid backing up through the same canaliculus being irrigated points to a canalicular obstruction
  • Fluid backing up through the opposite canaliculus points to a nasolacrimal duct obstruction
  • Probing the canaliculus with a Bowman probe localizes the level of a canalicular blockage
  • Schirmer testing measures reflex tearing, but many dry-eye patients still test normal on it
  • One referral practice found dry eye responsible for about 40 percent of its epiphora cases
  • Meibomian gland dysfunction with tear-film instability was the main cause of tearing in up to 20 percent of chronic epiphora patients
  • Botulinum toxin injected into the lacrimal gland relieves crocodile tears for three to four months

If not this — what else fits (7)

  • Punctal problems such as stenosis, membrane, ectropion, or plugging account for roughly 35 percent of adult epiphora
  • Canalicular disease, such as stenosis, infection, or scarring, accounts for roughly 15 percent of cases
  • Nasolacrimal duct obstruction, mostly primary acquired, accounts for roughly 24 percent of cases
  • Weakness of the tear pump, from eyelid laxity, facial nerve palsy, or floppy eyelid syndrome, accounts for roughly 11 percent
  • Pseudoepiphora, reflex tearing from dry eye or ocular inflammation rather than a drainage problem, accounts for roughly 11 percent
  • Nasal and sinus disease accounts for roughly 4 percent of cases
  • Aberrant nerve regeneration after facial palsy accounts for roughly 2 percent of cases

SourceStatPearls "Epiphora" - disease-level clinical article

Presentation findings are traced to the source above.

Rx: Ocular surface lubricant, where dryness is driving the tearing | Main treatment

OCULAR SURFACE LUBRICANT, WHERE DRYNESS IS DRIVING THE TEARING

1

HYPROMELLOSE

Ocular surface lubricant, where dryness is driving the tearing

1st line

Formeye

Adult dose and duration

1 or 2 drops into the affected eye as needed - For as long as the surface irritation lasts; review if the watering does not settle

Paediatric dose

1 or 2 drops as needed, the same as an adult. Watering in an infant is usually congenital nasolacrimal duct obstruction, which is managed by massage and hygiene rather than by a lubricant.

Dose source

Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.

Why

The epiphora article describes evaporative loss from an unstable tear film stimulating the lacrimal gland to over-produce, so a dry eye presents as a watering one; it reports dry eyes as the cause in 40% of patients in a tertiary oculoplastic practice, and says treating surface irritation with lubrication can reduce the reflex tearing. It also puts teaching a good lubrication technique among the things that matter most for these patients.

Cautions
  • Lubrication treats only the watering that comes from a dry, irritated surface. It does nothing for a blocked nasolacrimal duct, an in-turned or out-turned lid, or a weak lacrimal pump - the article puts punctal, canalicular and nasolacrimal obstruction together at well over half of chronic cases, and each needs a surgical opinion.
  • Review what the patient is already instilling. The article names anti-glaucoma drops, pilocarpine, phospholine iodide and idoxuridine among the medicines that can themselves obstruct the lacrimal drainage.
  • One-sided watering points to a local cause; both eyes watering is more often over-production from allergy or keratoconjunctivitis.
  • If the watering persists after a fair trial of lubrication, refer - the article's options from there are punctoplasty, balloon dacryoplasty or dacryocystorhinostomy, chosen by where the obstruction sits.
Egyptian brands
Egyptian brandManufacturerIndicative price
HYDROBLEND 0.32% EYE DROPS 10*0.5 ML SDUGLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS15.00 EGP
GENTEAL EYE DROPS 10 MLNOVARTIS > NOVARTIS SCIENTIFIC OFFICE18.00 EGP
OPTILUBRIC 0.32% EYE DROPS 30*0.5 ML SDUEVA PHARMA96.00 EGP
HYDROBLEND 0.32% EYE DROPS 30*0.5 ML SDUGLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS108.00 EGP

MAIN TREATMENT

2

REFERRAL & SAFETY-NETTING (NO DRUG THERAPY)

1st line
Adult dose and duration

Overflow of tears from poor drainage (nasolacrimal duct blockage, eyelid malposition) or from reflex overproduction (irritation, allergy, infection). Since the right response depends on the cause, there is no single drug to point to here; a GP's role is examining for a treatable cause and referring (for example for duct probing or lid surgery) when indicated. - Refer, with advice

Paediatric dose

The drug rows above are instilled, not dosed by weight. The referral threshold and the safety-netting are the same at any age.

Dose source

No dose - referral pathway, no medicine given in primary care

Why

Overflow of tears from poor drainage (nasolacrimal duct blockage, eyelid malposition) or from reflex overproduction (irritation, allergy, infection). Since the right response depends on the cause, there is no single drug to point to here; a GP's role is examining for a treatable cause and referring (for example for duct probing or lid surgery) when indicated.

Cautions
  • The drug rows above are what the treating service gives. They are here so that the referral is an informed one and so the GP can recognise the regimen the patient comes back on - not as permission to start it without the referral.
  • RED FLAG - A firm, hard, non-fluctuant medial canthal mass or bloody tear discharge indicates a possible lacrimal sac tumor requiring urgent specialist evaluation.
  • RED FLAG - Erythema, swelling, and tenderness over the lacrimal sac indicate acute dacryocystitis requiring prompt treatment and evaluation.
  • A watery eye accompanied by pain, redness, or vision change suggests infection or another eye disease rather than simple duct blockage, and in an infant a persistently watery, mucky eye since birth suggests congenital duct obstruction.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.