{ "schema_version": 1, "kind": "condition", "id": "tinea-infection", "name": "Tinea infections", "category": "infectious", "sources": "BAD Guidelines Tinea 2014 · DailyMed Clotrimazole 1% Cream Package Insert (DailyMed, NLM) · DailyMed Ketoconazole Cream 2% Package Insert, SetID ea56cddf-94c9-46b6-8791-995b741cfbd7 · DailyMed Miconazole Nitrate 2% Cream Package Insert (DailyMed, NLM) · UK eMC Terbinafine 250mg Tablet SmPC (Aurobindo Pharma - Milpharm Ltd.), product id 7133 · Tinea Corporis - StatPearls - NCBI Bookshelf (NBK544360) - disease-level clinical article · Egyptian National Drug Formulary - Antimicrobial 2023 (ketoconazole monograph, US Boxed Warnings)", "review_status": "reviewed", "verified_against": "DailyMed Clotrimazole 1% Cream Package Insert (DailyMed, NLM) · DailyMed Ketoconazole Cream 2% Package Insert, SetID ea56cddf-94c9-46b6-8791-995b741cfbd7 · DailyMed Miconazole Nitrate 2% Cream Package Insert (DailyMed, NLM) · UK eMC Terbinafine 250mg Tablet SmPC (Aurobindo Pharma - Milpharm Ltd.), product id 7133 · Tinea Corporis - StatPearls - NCBI Bookshelf (NBK544360) - disease-level clinical article · Egyptian National Drug Formulary - Antimicrobial 2023 (ketoconazole monograph, US Boxed Warnings)", "verified_date": "2026-08", "treatments": [ { "id": 1794, "generic": "Clotrimazole", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 1% cream thin layer to affected area twice daily", "adult_duration": "2-4 weeks", "dose_source": "DailyMed Clotrimazole 1% Cream Package Insert (DailyMed, NLM)", "rationale": "Topical azole antifungal that disrupts fungal cell membrane synthesis; a first-line topical treatment for localised tinea infection of the skin.", "cautions": [ "Continue for 14 days after lesion clearance to prevent recurrence.", "Local skin irritation, burning, or redness may occur.", "Avoid contact with eyes." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply BID in children; safe from infancy", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "CANEMAZOLE 1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CANDISTAN 1% TOPICAL CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ARAB DRUG COMPANY (ADCO)", "price_egp": 7.25, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DERMATIN 1% TOP. CREAM 14 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 14000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CANESTEN 1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS > BAYER HEALTHCARE", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LOCASTEN 1% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CANDISTAN 1% TOPICAL CREAM 40 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ARAB DRUG COMPANY (ADCO)", "price_egp": 36.0, "pack_count": null, "unit_price": null, "strength_mg": 40000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "tinea-infection" }, { "id": 1795, "generic": "Miconazole", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 2% cream to the affected area twice daily", "adult_duration": "2-3 weeks", "dose_source": "Tinea Corporis - StatPearls - NCBI Bookshelf (NBK544360) - disease-level clinical article", "rationale": "Topical azole antifungal that disrupts fungal cell membrane ergosterol synthesis; the cited article lists miconazole 2% twice daily among the recommended topical regimens for localised tinea corporis.", "cautions": [ "Topical miconazole can enhance warfarin effect via skin absorption.", "The endpoint of therapy is the clinical resolution of symptoms.", "Avoid eyes and mucous membranes." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply twice daily in children", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "MICONOL 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DERMOZOL 2% GEL 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MICOBAN 2% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MICONAZ 2% CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MICONAZ 2% ORAL GEL 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DAKTARIN 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > JANSSEN CILAG", "price_egp": 28.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DAKTARIN 2% ORAL GEL 40 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JANSSEN CILAG > SOFICOPHARM", "price_egp": 53.5, "pack_count": null, "unit_price": null, "strength_mg": 40000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ADCOZOLE 2% TOPICAL CR. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 7.25, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "tinea-infection" }, { "id": 1796, "generic": "Terbinafine", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 250.0, "adult_dose": "250 mg once daily for 2-4 weeks (tinea corporis/cruris) or 2-6 weeks (tinea pedis)", "adult_duration": "2-4 weeks for tinea corporis or cruris, 2-6 weeks for tinea pedis", "dose_source": "UK eMC Terbinafine 250mg Tablet SmPC (Aurobindo Pharma - Milpharm Ltd.), product id 7133", "rationale": "Oral allylamine antifungal that inhibits fungal squalene epoxidase; reserved for extensive or recalcitrant tinea infection not responding to topical therapy.", "cautions": [ "Indicated for extensive or recalcitrant tinea infections.", "Taste disturbance (ageusia) can occur and persist after stopping.", "Rare hepatotoxicity can occur - check baseline LFTs." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Specialist use only in children; weight-based dosing for tinea capitis under specialist supervision", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "TRERBI 250 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MASH PREMIERE", "price_egp": 26.4, "pack_count": 10, "unit_price": 2.64, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MYCOMIC 250 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > TABUK PHARMA", "price_egp": 26.5, "pack_count": 10, "unit_price": 2.65, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MYCOMIC 250 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > TABUK PHARMA", "price_egp": 53.0, "pack_count": 20, "unit_price": 2.65, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "UNITOPFIN 250 MG 7 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 25.2, "pack_count": 7, "unit_price": 3.6, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FUNGISAFE 250MG 7 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMOUN", "price_egp": 32.0, "pack_count": 7, "unit_price": 4.57, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TERBIN 250 MG 14 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 120.0, "pack_count": 14, "unit_price": 8.57, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TERBINASIL 250 MG 7 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JAMJOOM PHARMACEUTICALS-K.S.A", "price_egp": 68.0, "pack_count": 7, "unit_price": 9.71, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LAMISIL 250MG 14 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS", "price_egp": 146.5, "pack_count": 14, "unit_price": 10.46, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LAMISIL ONCE 4G FILM FORMING SOLUTION.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS", "price_egp": 50.0, "pack_count": null, "unit_price": null, "strength_mg": 4000.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "tinea-infection" }, { "id": 1797, "generic": "Ketoconazole", "line": 2, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 2% cream once daily to cover the affected and immediate surrounding area", "adult_duration": "2-4 weeks (tinea corporis/cruris); 6 weeks for tinea pedis", "dose_source": "DailyMed Ketoconazole Cream 2% Package Insert, SetID ea56cddf-94c9-46b6-8791-995b741cfbd7", "rationale": "Topical azole antifungal alternative for tinea, used as a cream only: the ENDF's own ketoconazole monograph carries a US Boxed Warning that ketoconazole tablets are \"not indicated for the treatment of onychomycosis, cutaneous dermatophyte infections, or Candida infections\", and a second for hepatotoxicity \"including fatal cases and cases requiring liver transplantation\".", "cautions": [ "Topical use only. The ENDF's own ketoconazole monograph carries a US Boxed Warning, verbatim: \"Ketoconazole tablets are not indicated for the treatment of onychomycosis, cutaneous dermatophyte infections, or Candida infections.\" and a second one: \"Ketoconazole has been associated with hepatotoxicity, including fatal cases and cases requiring liver transplantation; some patients had no apparent risk factors for hepatic disease.\"", "Continue for a few days after clearance.", "Local irritation may occur." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply once daily in children", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "KONAZOLE 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CURAZOLE 2% TOPICAL CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KETODERM 2% TOP. CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NIZODERM 2% CREAM 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "WELLOFUNG 2% TOPICAL CREAM 40 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > HEALTH WELL", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 40000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KENZO 2% SHAMPOO 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BORG", "price_egp": 27.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZAKAN 2GM/100ML SHAMPOO 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 18.3, "pack_count": null, "unit_price": null, "strength_mg": 2000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NIZAPEX 20MG/GM SHAMPOO 80 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "APEX PHARMA", "price_egp": 68.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "tinea-infection" } ] }