{ "schema_version": 1, "kind": "condition", "id": "testicular-pain", "name": "Pain in the testis (scrotal pain)", "category": "acute", "sources": "BASHH UK national guideline for the management of epididymo-orchitis 2020 (Int J STD AIDS 2021;32(10):884-895), Treatment recommendations · Egyptian National Drug Formulary - antimicrobial-2023.pdf, Doxycycline monograph (chapter PDF p297) · Egyptian National Drug Formulary - antimicrobial-2023.pdf, Ofloxacin monograph (chapter PDF p394)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 · BASHH UK national guideline for the management of epididymo-orchitis 2020 (Int J STD AIDS 2021;32(10):884-895), Treatment recommendations", "verified_date": "2026-08", "treatments": [ { "id": 1767, "generic": "Doxycycline", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 100.0, "adult_dose": "100 mg by mouth twice daily", "adult_duration": "10-14 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph): \"100 to 200 mg/day in 1 to 2 divided doses\", 100 mg capsules; the epididymo-orchitis indication and the 10-to-14-day course are from the BASHH UK national guideline for the management of epididymo-orchitis 2020, which is not held in this corpus.", "rationale": "Half of BASHH's first-line regimen for sexually acquired epididymo-orchitis, given with ceftriaxone. Given alone it is the regimen for disease probably due to chlamydia or other non-gonococcal organisms, where gonorrhoea has been excluded.", "cautions": [ "TESTICULAR TORSION FIRST. Sudden severe pain, a high-riding or transversely lying testis, or onset in a boy or young man is torsion until proved otherwise, and the testis is lost in hours. Refer the same hour; do not start antibiotics and review.", "The formulary's 7-day course is for chlamydial urethritis. Epididymo-orchitis needs 10 to 14 days - a short course here is a treatment failure with a testis at stake.", "Test for chlamydia and gonorrhoea, and treat sexual partners.", "Not in pregnancy, not in children, and not with retinoid therapy." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "BASHH wrote this guideline for people aged 16 and over. Acute scrotal pain in a boy is torsion until a surgeon says otherwise - refer, do not treat.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FARCODOXIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXY M.R.100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANUDOXY 100MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE FRANCE", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYDOX 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYMYCIN 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABOCINE 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 46.0, "pack_count": 10, "unit_price": 4.6, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIBRAMYCIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "testicular-pain" }, { "id": 1768, "generic": "Ceftriaxone", "line": 1, "is_adjunct": false, "form": "injection", "strength_mg": 1000.0, "adult_dose": "1 g intramuscularly as a single dose", "adult_duration": "Single dose, given with the doxycycline course", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (ceftriaxone monograph), General Adult Dosage: \"IV or IM 1-2 g once or devided twice daily\", 1 gm vial; the epididymo-orchitis indication and single-dose regimen are from the BASHH UK national guideline for the management of epididymo-orchitis 2020, which is not held in this corpus.", "rationale": "BASHH raised this to 1 g in line with its gonorrhoea guideline, to cover strains with reduced susceptibility. It is given with doxycycline, not instead of it.", "cautions": [ "Given WITH doxycycline as one regimen. Ceftriaxone alone does not treat the chlamydia that causes most of these.", "Ask about penicillin and cephalosporin allergy before giving it." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not applicable - this guideline covers people aged 16 and over. A boy with acute scrotal pain is a surgical referral.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ZOXIDEL 1 GM PD. FOR I.M. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > DELTA PHARMA", "price_egp": 22.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFTRIAXONE SODIUM 1 GM I.M.VIAL (KAHIRA)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZOXIDEL 1 GM PD. FOR I.V. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > DELTA PHARMA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "WINTRIAXONE 1 GM PD. FOR I.V INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VOTRIAXONE 1 GM I.M VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHEMIPHARM", "price_egp": 56.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFRAMAX 1 GM I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > SUN PHARMA EGYPT LIMITED", "price_egp": 71.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.V VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "testicular-pain" }, { "id": 1769, "generic": "Ofloxacin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 200.0, "adult_dose": "200 mg by mouth twice daily", "adult_duration": "14 days", "dose_source": "BASHH UK national guideline for the management of epididymo-orchitis 2020 (Int J STD AIDS 2021;32(10):884-895), Treatment recommendations", "rationale": "The alternative where gonorrhoea has been excluded, and the choice where an enteric organism is likely - an older man, recent instrumentation, or a urine dipstick positive for leucocytes and nitrites. BASHH also offers levofloxacin 500 mg once daily there.", "cautions": [ "Fourteen days, not seven.", "Fluoroquinolones carry tendon rupture and aortic aneurysm warnings, and the risk rises with age and with concurrent corticosteroids.", "A confirmed uropathogen is an indication for urology referral to exclude a structural abnormality or obstruction." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Fluoroquinolones are avoided in children other than in specific circumstances. Refer.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "JEDCOFLACIN 200 MG 20 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS", "price_egp": 43.25, "pack_count": 20, "unit_price": 2.16, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXIN 200MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 21.6, "pack_count": 10, "unit_price": 2.16, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLICIN 200MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 24.0, "pack_count": 10, "unit_price": 2.4, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPICOFLOCIN 200 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 28.0, "pack_count": 10, "unit_price": 2.8, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXACIN 200MG 10 TAB", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KIROLL 200MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 34.5, "pack_count": 10, "unit_price": 3.45, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TARIVAN 200MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 44.0, "pack_count": 10, "unit_price": 4.4, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TARIVID 200MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 82.0, "pack_count": 10, "unit_price": 8.2, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "testicular-pain" } ] }