{ "schema_version": 1, "kind": "condition", "id": "scrotal-testicular-symptoms", "name": "Scrotal or Testicular Symptoms", "category": "chronic", "sources": "Acute Scrotum Pain - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK470404/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class GS21 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care · Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose for this indication · Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose and duration for this indication", "review_status": "reviewed", "verified_against": "No dose - referral pathway, no medicine given in primary care · Chronic Testicular Pain and Orchalgia - disease-level clinical article (scrotal-testicular-symptoms-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 1654, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": "A broad symptom category covering pain, lumps, and other scrotal complaints; a GP can give pain relief but the differential (torsion, tumour, hernia, infection) needs urgent ultrasound and urology input.", "adult_duration": "Refer, with advice", "dose_source": "No dose - referral pathway, no medicine given in primary care", "rationale": "A broad symptom category covering pain, lumps, and other scrotal complaints; a GP can give pain relief but the differential (torsion, tumour, hernia, infection) needs urgent ultrasound and urology input.", "cautions": [ "Referral is the pathway; the medicines listed alongside are what primary care can give before or while it happens.", "RED FLAG - Amiodarone-induced orchialgia is not noted as a potential drug-induced cause requiring drug discontinuation", "RED FLAG - Sudden severe scrotal pain, which may be testicular torsion and a surgical emergency, or a hard, painless, irregular testicular mass, which may be testicular cancer." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children follow the same pathway: recognise and refer. No primary-care medicine is implied.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "scrotal-testicular-symptoms" }, { "id": 1657, "generic": "Ibuprofen", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 600.0, "adult_dose": "600 mg three times daily", "adult_duration": "At least 30 days before deciding it has not worked", "dose_source": "Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose and duration for this indication", "rationale": "A man with months of scrotal ache, once the emergencies have been ruled out, still needs analgesia. This is the article's first pharmacological step.", "cautions": [ "Only after torsion, epididymo-orchitis and a testicular mass have been excluded - a sudden painful testis is a same-day surgical problem, not an NSAID problem.", "Do not give it to anyone who has had asthma, hives or an allergic reaction after aspirin or another NSAID.", "A month of a full-dose NSAID is a real ulcer and kidney risk - think about gastroprotection and check the kidney function in older men." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "No paediatric dose for this indication in the sources opened.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "DAJUANOFEN 600 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "COPAD PHARMA", "price_egp": 6.5, "pack_count": 20, "unit_price": 0.33, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLABU 600 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA PHARMA", "price_egp": 9.5, "pack_count": 20, "unit_price": 0.47, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MAXIPROFEN 600MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 4.75, "pack_count": 10, "unit_price": 0.47, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLAMOTAL 600 MG 20 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > FUTURE PHARMACEUTICAL INDUSTRIES (FPI)", "price_egp": 56.0, "pack_count": 20, "unit_price": 2.8, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALPHAFEN 600MG 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 86.0, "pack_count": 30, "unit_price": 2.87, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEN 600 MG 30 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 99.0, "pack_count": 30, "unit_price": 3.3, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEN 600 MG 20 EFF. GR. IN SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 120.0, "pack_count": null, "unit_price": null, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SPIDIDOL 600 MG 12 EFF. GR. IN SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ZAMBON > PHARMACON", "price_egp": 132.0, "pack_count": null, "unit_price": null, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVA-PROFEN 100MG/5ML ORAL SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 2.25, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEMOL-N SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 4.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "scrotal-testicular-symptoms" }, { "id": 1655, "generic": "Amitriptyline", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 25.0, "adult_dose": "25 mg as a single dose at bedtime", "adult_duration": "Allow at least 2 to 4 weeks, and sometimes up to 8 weeks, before judging it", "dose_source": "Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose for this indication", "rationale": "For a man with months of scrotal ache once the emergencies are excluded, this is the article's second step and a GP can prescribe it.", "cautions": [ "This is for long-standing scrotal pain, not for a sudden painful testis - that needs same-day assessment for torsion.", "Never combine it with a monoamine oxidase inhibitor.", "Expect sedation, dry mouth and postural dizziness; be careful in the elderly, in glaucoma and where urinary retention is already a problem." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Safety and effectiveness in children have not been established.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "TRYPTIZOL 25 MG 30 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 33.0, "pack_count": 30, "unit_price": 1.1, "strength_mg": 25.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANITYLLIN 25MG/5ML SYP. 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GRAND PHARMA > DELTA GRAND PHARMA", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 25.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ZINOTRAVAL 25MG/5ML SYP. 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DEBEIKY > PHARMACHEMIC", "price_egp": 10.0, "pack_count": null, "unit_price": null, "strength_mg": 25.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "scrotal-testicular-symptoms" }, { "id": 1656, "generic": "Gabapentin", "line": 3, "is_adjunct": false, "form": "oral.solid", "strength_mg": 300.0, "adult_dose": "300 mg three times daily", "adult_duration": null, "dose_source": "Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose for this indication", "rationale": "The article's third conservative step, reached when a month of tricyclic has not worked. It matters on a card that otherwise sends the man away with nothing.", "cautions": [ "It causes drowsiness and dizziness - tell the patient not to drive until he knows how it affects him.", "Reduce the dose in kidney impairment, and stop it gradually over at least a week rather than abruptly.", "This is for long-standing pain, not for a sudden painful testis." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "No paediatric dose for this indication in the sources opened.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "EZAPENTIN 300MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MULTI-APEX", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PENTALIPSY 300MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SAFE PHARMA", "price_egp": 14.4, "pack_count": 10, "unit_price": 1.44, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OCTOCONVAL 300 MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "OCTOBER PHARMA", "price_egp": 72.0, "pack_count": 30, "unit_price": 2.4, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NEUROGLOPENTIN 300 MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 111.0, "pack_count": 30, "unit_price": 3.7, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SHALGATEN 300MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > MASH PREMIERE", "price_egp": 126.0, "pack_count": 30, "unit_price": 4.2, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GABALEPSY 300MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 135.0, "pack_count": 30, "unit_price": 4.5, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GABAVERONA 300 MG 30 H.G. CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AVERROES PHARMA", "price_egp": 126.0, "pack_count": null, "unit_price": null, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SAJALIPSY 300 MG 30 H.G. CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SAJA PHARMACEUTICALS", "price_egp": 126.0, "pack_count": null, "unit_price": null, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "STABLENTIN 6MG/120ML SYRUP", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEPACO", "price_egp": 21.6, "pack_count": null, "unit_price": null, "strength_mg": 6.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ADAPTAN 250MG/5ML ORAL SOLUTION 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 37.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "scrotal-testicular-symptoms" }, { "id": 1658, "generic": "Pregabalin", "line": 3, "is_adjunct": false, "form": "oral.solid", "strength_mg": 75.0, "adult_dose": "75 mg to 150 mg daily", "adult_duration": null, "dose_source": "Chronic Testicular Pain and Orchalgia - StatPearls - NCBI Bookshelf (NBK482481) - the article states the dose for this indication", "rationale": "Same step as gabapentin in the article, kept as the alternative because the article says gabapentin is normally tried first. Useful where gabapentin's three-times-daily schedule or its side effects defeat the patient.", "cautions": [ "Stop it at once and treat as an emergency if the throat, face or neck swells.", "Taper it rather than stopping abruptly - withdrawal symptoms and seizures have followed sudden discontinuation.", "It is sedating and causes dizziness; warn about driving, and reduce the dose in kidney impairment." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "No paediatric dose for this indication in the sources opened.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FORPREGAB 75 MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GRAND PHARMA > PARKVILLE", "price_egp": 45.0, "pack_count": 30, "unit_price": 1.5, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SNAPGAB 75 MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MASH PREMIERE > TA PHARMA", "price_egp": 49.5, "pack_count": 30, "unit_price": 1.65, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LYRIBALIN 75MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BORG", "price_egp": 18.0, "pack_count": 10, "unit_price": 1.8, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NEURAGABALIN 75 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA GRAND PHARMA", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NERVATYCA 75 MG 20 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 48.75, "pack_count": 20, "unit_price": 2.44, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "QUEENLEPT 75 MG 30 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > ASPIN PHARMACEUTICAL", "price_egp": 93.0, "pack_count": 30, "unit_price": 3.1, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LYRICA 75MG 20 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 232.0, "pack_count": 20, "unit_price": 11.6, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREGABEDIUM 75 MG 20 H.G. CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SABAA > ACTIVA THERAPEUTICS", "price_egp": 56.66, "pack_count": null, "unit_price": null, "strength_mg": 75.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LOCIKASWAB 100MG/5ML 20 UNIDOSE ORAL SOLN.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNISWAB > VODACHEM", "price_egp": 43.5, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "AVEROPREG 100MG/5ML SYRUP 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AVERROES PHARMA-EGYPT", "price_egp": 55.5, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "scrotal-testicular-symptoms" } ] }