# Pulp Space Infection of the Toe

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361) · Nardi NM, McDonald EJ, Syed HA, et al. Felon. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK430933.
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361)

## Treatment metadata

- Flucloxacillin — oral.solid

## Complete treatment card

```text
PULP SPACE INFECTION OF THE TOE
Sources: Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph
         (chapter PDF p361) · Nardi NM, McDonald EJ, Syed HA, et al. Felon. In: StatPearls
         [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. NBK430933.
Review status: REVIEWED against the source listed above  (2026-08)

1. FLUCLOXACILLIN                                         [1st line]
   Adult    250 mg orally (or by intramuscular injection) four times daily; the dose may be doubled
            for a severe infection.
   Peds     Paediatric dosing is specialist-set and is not reproduced here.
   Source   Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph
            (chapter PDF p361)
   Why      A toe pulp infection is a closed-space staphylococcal soft-tissue infection, matching
            flucloxacillin's formulary indication for staphylococcal skin and soft-tissue
            infections; extra caution and a lower referral threshold apply in diabetic patients.
   Caution  Penicillin allergy is a contraindication - ask about prior reactions before prescribing.
            A fluctuant abscess needs incision and drainage referral rather than antibiotics alone.
            Diabetic patients have a lower threshold for referral given the risk of rapid spread and
            poor healing in the foot.
            Spreading cellulitis or signs of systemic infection need urgent reassessment.
            Rare but serious cholestatic jaundice/hepatitis can occur, more often with longer
            courses and in older patients.
            Oral: Take flucloxacillin on an empty stomach. This means 30 to 60 minutes before a meal
            or snack, or at least 2 hours after.
   Egypt    FLUMOCIN 250MG 12CAPS.           UP PHARMA            6.20 EGP (0.52/unit)
                -> ! also contains amoxicillin
            AMOFLUX 125/125MG 12 CAPS.       RAMEDA > DELT...     8.25 EGP (0.69/unit)
                -> ! also contains amoxicillin
            FLUCAMOX 250MG 12CAPS.           SEDICO               8.25 EGP (0.69/unit)
                -> ! also contains amoxicillin
            FLUMOCIN 500MG 8 CAPS.           UP PHARMA            6.00 EGP (0.75/unit)
                -> ! also contains amoxicillin
            CURAFLUX 125/125 MG 12 CAPS.     RAMEDA > PIONEER    12.50 EGP (1.04/unit)
                -> ! also contains amoxicillin
            AMOFLUX 250/250MG 16 CAPS.       RAMEDA > PIONEER    18.00 EGP (1.12/unit)
                -> ! also contains amoxicillin
            HI-FLUCIL 250/250MG 16 CAPS.     CID                 20.00 EGP (1.25/unit)
                -> ! also contains amoxicillin
            AMPIFLUX 500 MG 12 CAPS.         PHARCO              16.00 EGP (1.33/unit)
                -> ! also contains ampicillin

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement.

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