{ "schema_version": 1, "kind": "condition", "id": "pruritus-generalized", "name": "Pruritus (itching)", "category": "acute", "sources": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef · Levocetirizine dihydrochloride tablets US prescribing information, sections 1 and 2 Dosage and Administration (DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef) · No labelled dose - emollient applied liberally and as often as needed, to effect · SmPC sections 4.2 and 4.4, https://www.medicines.org.uk/emc/product/5453/smpc", "review_status": "reviewed", "verified_against": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef · SmPC sections 4.2 and 4.4, https://www.medicines.org.uk/emc/product/5453/smpc", "verified_date": "2026-08", "treatments": [ { "id": 1551, "generic": "Liquid paraffin", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply to affected areas as often as required.", "adult_duration": "long-term continuous maintenance", "dose_source": "SmPC sections 4.2 and 4.4, https://www.medicines.org.uk/emc/product/5453/smpc", "rationale": "Regular emollient use restores skin barrier function and is first-line, safe symptomatic treatment for itch regardless of the underlying cause, the same role it plays in eczema.", "cautions": [ "Generalised itching without a rash may indicate underlying liver disease, chronic kidney disease, thyroid disease, or lymphoma and needs systemic work-up.", "Dry skin is one of the commonest causes of generalised itch, especially with frequent washing; regular emollient use is first-line and should continue even once itching settles.", "If itching is generalised with no visible rash, screen for systemic causes - liver disease, chronic kidney disease, thyroid disease, iron deficiency, or lymphoma - rather than treating with emollient alone indefinitely.", "Warn about fire hazard when fabric contacts paraffin-based products." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Apply to affected areas as often as required. Warning: fire hazard with paraffin-soaked fabrics.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ADCOCARE CREAM 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "glyceryl monostearate, propylene glycol, urea" }, { "trade_name": "DERMOLAN CREAM 50 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HI-CARE > EMICO PHARMA", "price_egp": 19.0, "pack_count": null, "unit_price": null, "strength_mg": 50000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "allantoin, glycerol, glycolic acid, panthenol, salicylic acid, urea, vitamin c, zinc oxide" }, { "trade_name": "ADCOCARE CREAM 40 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 21.75, "pack_count": null, "unit_price": null, "strength_mg": 40000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "glyceryl monostearate, propylene glycol, urea" }, { "trade_name": "CARE MIX PLUS HAIR CREAM 50 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "VITA PHARM > CARE MIX", "price_egp": 29.5, "pack_count": null, "unit_price": null, "strength_mg": 50000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cetostearyl alcohol, lanolin, panthenol, wheat protein, white soft paraffin" }, { "trade_name": "PROPOLIS CREAM 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LUNA FOR PERFUMES AND COSMETICS > TECHNOMED GROUP", "price_egp": 30.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cera alba, glycerin, propolis" }, { "trade_name": "PROPOLIS CREAM 30 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LUNA FOR PERFUMES AND COSMETICS > TECHNOMED GROUP", "price_egp": 55.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "cera alba, glycerin, propolis" }, { "trade_name": "HEALTHPOINT NAPPY CREAM 100 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HEALTHPOINT LTD. > PAXTON", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": 100000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "benzyl alcohol, cetearyl alcohol, glyceryl stearate, lanolin, peg-100 s, water, zinc oxide" }, { "trade_name": "HERCUL WHITENING CREAM 60 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "LEADER FOR COSMETICS > JUNIER PHARMA", "price_egp": 74.75, "pack_count": null, "unit_price": null, "strength_mg": 60000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "alpha arbutin, diemthicone, glycerin, licorice ext, octyl methoxy, titanium dioxide, vit.c" } ], "condition_id": "pruritus-generalized" }, { "id": 1552, "generic": "Levocetirizine", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 5.0, "adult_dose": "5 mg PO once daily in evening (2.5 mg once daily may suffice).", "adult_duration": "While symptoms persist; review at 4-6 weeks", "dose_source": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef", "rationale": "An oral antihistamine is standard symptomatic treatment for troublesome itch of any hypersensitivity or unclear cause, at the same dose used for urticaria.", "cautions": [ "Evening dosing helps because itch is typically worse at night and this is the more sedating of the second-generation antihistamines.", "Sedating antihistamines give symptomatic relief but do not treat a systemic cause of itch if one is found on work-up.", "Reduce to 2.5 mg in mild renal impairment - a lower threshold than most drugs and easy to miss in the elderly." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Age 6-11y: 2.5 mg (1/2 scored tablet) PO once daily in evening; age <6y: use oral solution.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ZALKEVOR 5 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR > REPHARMA", "price_egp": 5.5, "pack_count": 10, "unit_price": 0.55, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RHIPGIC 5 MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "P & C LABS", "price_egp": 19.5, "pack_count": 30, "unit_price": 0.65, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LERGOPAN 5 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 7.5, "pack_count": 10, "unit_price": 0.75, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LEVOCITRONE 5 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGYPHAR", "price_egp": 21.0, "pack_count": 10, "unit_price": 2.1, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RAMATRIZINE 5 MG 30 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > RAMAPHARMA", "price_egp": 96.0, "pack_count": 30, "unit_price": 3.2, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LEVOHISTAM 5 MG 30 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > UTOPIA", "price_egp": 117.0, "pack_count": 30, "unit_price": 3.9, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ARAXILEVE 5 MG 30 ORO-DISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS > ARAX PHARM. IND.", "price_egp": 51.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LEVCET 5MG 20 ORODISSOLVABLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)", "price_egp": 85.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MERVOZA 2.5MG/5ML SYRUP 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 2.5, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "MODALLERGE 0.5MG/ML ORAL SOL.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > MODERN PHARMA", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": 0.5, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pruritus-generalized" } ] }