{ "schema_version": 1, "kind": "condition", "id": "pelvic-inflammatory-disease", "name": "Pelvic inflammatory disease (PID outpatient therapy)", "category": "infectious", "sources": "CDC STI Treatment Guidelines 2021 · Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (ofloxacin monograph) · BASHH UK national guideline for the management of pelvic inflammatory disease, 2018, with the 2019 interim update: \"i.m. ceftriaxone 1g single dose followed by oral doxycycline 100mg twice daily plus metronidazole 400mg twice daily for 14 days\" · BASHH 2019 Interim Update - UK National Guideline for the Management of Pelvic Inflammatory Disease (outpatient regimens, second line therapy) · MSF Essential Drugs 2024 - paracetamol (oral) · Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (ofloxacin monograph) · BASHH UK national guideline for the management of pelvic inflammatory disease, 2018, with the 2019 interim update: \"i.m. ceftriaxone 1g single dose followed by oral doxycycline 100mg twice daily plus metronidazole 400mg twice daily for 14 days\" · BASHH 2019 Interim Update - UK National Guideline for the Management of Pelvic Inflammatory Disease (outpatient regimens, second line therapy) · MSF Essential Drugs 2024 - paracetamol (oral) · Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560) · Pelvic Inflammatory Disease - disease-level clinical article (pelvic-inflammatory-disease-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 1403, "generic": "Ceftriaxone", "line": 1, "is_adjunct": false, "form": "injection", "strength_mg": 1000.0, "adult_dose": "1 g IM, one part of the three-drug regimen - with doxycycline and metronidazole below, not an alternative to them", "adult_duration": "Single dose", "dose_source": "BASHH UK national guideline for the management of pelvic inflammatory disease, 2018, with the 2019 interim update: \"i.m. ceftriaxone 1g single dose followed by oral doxycycline 100mg twice daily plus metronidazole 400mg twice daily for 14 days\"", "rationale": "Triple empiric regimen covering N. gonorrhoeae, C. trachomatis, and anaerobic vaginal flora", "cautions": [ "1 g, not 500 mg. BASHH raised the dose in its 2019 interim update; the older 500 mg figure is still widely quoted.", "MUST complete full 14-day oral course of doxycycline and metronidazole even after rapid symptom improvement.", "Screen and treat all sexual partners within past 60 days to prevent reinfection.", "Advise strict avoidance of sexual intercourse until treatment complete and partners treated.", "Inpatient admission is required if the patient is pregnant, a tubo-ovarian abscess is suspected, or she is unable to tolerate the oral regimen." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Adolescent regimen identical to adult dose", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ZOXIDEL 1 GM PD. FOR I.M. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > DELTA PHARMA", "price_egp": 22.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFTRIAXONE SODIUM 1 GM I.M.VIAL (KAHIRA)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZOXIDEL 1 GM PD. FOR I.V. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > DELTA PHARMA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "WINTRIAXONE 1 GM PD. FOR I.V INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VOTRIAXONE 1 GM I.M VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHEMIPHARM", "price_egp": 56.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFRAMAX 1 GM I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > SUN PHARMA EGYPT LIMITED", "price_egp": 71.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.V VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1404, "generic": "Doxycycline", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 100.0, "adult_dose": "100 mg orally twice daily", "adult_duration": "14 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (doxycycline monograph)", "rationale": "Covers Chlamydia trachomatis, which ceftriaxone does not. Leaving it out treats the gonococcus and misses the commonest cause.", "cautions": [ "Contraindicated in pregnancy. PID in a pregnant woman needs hospital admission, not this regimen.", "Swallow with a full glass of water sitting upright, and not at bedtime - the capsule ulcerates the oesophagus if it lodges.", "Photosensitivity is common and matters in Egyptian sun; advise cover and sunscreen for the 14 days.", "Separate from antacids, iron, and dairy by 2 hours, which otherwise bind the dose.", "The full 14 days must be completed even once the pain settles, or the infection recurs and the tubes scar." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Adolescent regimen identical to the adult dose. Avoid under 8 years except in a severe infection with no alternative.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FARCODOXIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 11.0, "pack_count": 10, "unit_price": 1.1, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXY M.R.100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GRANUDOXY 100MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE FRANCE", "price_egp": 12.0, "pack_count": 10, "unit_price": 1.2, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYDOX 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": 10, "unit_price": 2.3, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DOXYMYCIN 100 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 30.0, "pack_count": 10, "unit_price": 3.0, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABOCINE 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 46.0, "pack_count": 10, "unit_price": 4.6, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIBRAMYCIN 100MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 65.0, "pack_count": 10, "unit_price": 6.5, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1405, "generic": "Metronidazole", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500 mg orally twice daily - part of the line 1 regimen, and the partner drug for ofloxacin on line 2", "adult_duration": "14 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph)", "rationale": "Covers the anaerobes found in PID, and the bacterial vaginosis that so often accompanies it.", "cautions": [ "Treat the sexual partner as well, and abstain until both have finished, or she is reinfected.", "Metallic taste and nausea are expected and are not a reason to stop early.", "Strictly avoid alcohol and propylene glycol-containing products during treatment and for 3 days (72 hours) after the last dose - Egyptian National Drug Formulary, Antimicrobial 2023." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Adolescent regimen identical to the adult dose.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "DUMOZOL 500MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > ALPHARMA-DENMARK", "price_egp": 7.0, "pack_count": 20, "unit_price": 0.35, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZOLGUARD 500MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 9.0, "pack_count": 20, "unit_price": 0.45, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NITROFECTAZOLE 500 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GYPTO PHARMA", "price_egp": 10.5, "pack_count": 20, "unit_price": 0.53, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLAGICURE FORTE 500 MG 20 F.C. TAB", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 23.0, "pack_count": 20, "unit_price": 1.15, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRICHOGYL 500MG 12 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 15.0, "pack_count": 12, "unit_price": 1.25, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLAGELLAT FORTE 500MG 20 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 30.0, "pack_count": 20, "unit_price": 1.5, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GEDAZOLE 500MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS", "price_egp": 34.0, "pack_count": 20, "unit_price": 1.7, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "METROGYPTON 500 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GYPTO PHARMA", "price_egp": 34.0, "pack_count": 20, "unit_price": 1.7, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DUMOZOL 125MG/5ML SUSP. 125ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > ALPHARMA-DENMARK", "price_egp": 5.75, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "METROZOLE 125MG/5ML SUSP. 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1410, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Pelvic Inflammatory Disease - disease-level clinical article (pelvic-inflammatory-disease-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - The indications for hospitalization instead of outpatient therapy are pregnancy, failed outpatient treatment, severe illness with vomiting/fever >38.5C, pelvic abscess, or possible need for surgery.", "RED FLAG - A tubo-ovarian abscess needs surgical drainage, especially if it is large, has ruptured, or the patient is septic." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1406, "generic": "Ofloxacin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 400.0, "adult_dose": "400 mg orally twice daily, given with metronidazole 500 mg twice daily - the same metronidazole course shown in the line 1 regimen", "adult_duration": "14 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (ofloxacin monograph)", "rationale": "Alternative oral regimen where parenteral cephalosporin is contraindicated", "cautions": [ "The fluoroquinolone black box warning covers tendinitis, tendon rupture, peripheral neuropathy, and CNS effects.", "There is high local quinolone resistance in N. gonorrhoeae; use ofloxacin only when cephalosporin allergy is confirmed." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Contraindicated in children under 18 years", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "GRAND Q 400 MG 10 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA GRAND PHARMA", "price_egp": 19.2, "pack_count": 10, "unit_price": 1.92, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOGUIDE 400MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIORIGINAL INTERNATIONAL GROUP PHARMA > GENESIS PHARMACEUTICALS", "price_egp": 28.8, "pack_count": 10, "unit_price": 2.88, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEMI-FLOX 400MG 10 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CAPS > MASTER MED PHARMA", "price_egp": 29.0, "pack_count": 10, "unit_price": 2.9, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TARIFLOX 400 MG 10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BORG", "price_egp": 45.0, "pack_count": 10, "unit_price": 4.5, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "UNITARQIN 400 MG 10 SCORED F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 38.0, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HEALTHIBACT 400MG 10 SCORED F.C.TAB", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > HEALTH WELL EGYPT", "price_egp": 38.5, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1407, "generic": "Moxifloxacin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 400.0, "adult_dose": "400 mg orally once daily as the whole regimen - no ceftriaxone, no doxycycline, no metronidazole alongside it", "adult_duration": "14 days", "dose_source": "BASHH 2019 Interim Update - UK National Guideline for the Management of Pelvic Inflammatory Disease (outpatient regimens, second line therapy)", "rationale": "The only single-drug PID regimen, and the one the guideline says covers Mycoplasma genitalium best. It matters here because it is one tablet a day for 14 days against three drugs including an injection, and adherence to the 14-day course is the thing that decides whether the tubes scar.", "cautions": [ "Second line, not first. The 2019 update moved the quinolones down because of disabling and potentially permanent tendon, muscle, joint and nervous system effects - the exception is M. genitalium PID where nothing else works.", "Given alone. It is not added to the ceftriaxone regimen and the metronidazole is not needed with it.", "Avoid where gonococcal PID is likely - the partner has gonorrhoea, the disease is clinically severe, or there was sexual contact abroad - because of quinolone resistance.", "Rare but real risk of serious liver reactions; stop for jaundice, dark urine or right upper quadrant pain.", "QT prolongation - check for other QT-prolonging drugs before writing it." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not licensed under 18 years. The guideline states quinolones are not licensed for use in patients aged under 18.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "MOXILABACT 400 MG 5 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 30.6, "pack_count": 5, "unit_price": 6.12, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GASTAMOXACINE 400MG 7 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES > GAST PHARMA GROUP-EGYPT", "price_egp": 45.0, "pack_count": 7, "unit_price": 6.43, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MERAMERIX 400MG 5 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARMED HEALTHCARE > ABBOTT LABORATORIES", "price_egp": 40.5, "pack_count": 5, "unit_price": 8.1, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "IDELOX 400MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA", "price_egp": 116.0, "pack_count": 10, "unit_price": 11.6, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PRIMOXIZAR 400 MG 5 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARMA CURE PHARMACEUTICALS > PHARMA CURE", "price_egp": 80.0, "pack_count": 5, "unit_price": 16.0, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MOXIFLOX 400 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 180.0, "pack_count": 10, "unit_price": 18.0, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MOXAVIDEX 400 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > UTOPIA", "price_egp": 184.0, "pack_count": 10, "unit_price": 18.4, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MOXAVIDEX 400 MG 5 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > UTOPIA", "price_egp": 92.0, "pack_count": 5, "unit_price": 18.4, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MOXIFLOXACIN-EL NILE 400MG/250ML SOL. FOR INF.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 80.5, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "MOXITRIX 400MG/250ML SOL. FOR INF.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CO. FOR MEDICAL PRODUCTS > SPIMACO MISR", "price_egp": 86.0, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1408, "generic": "Paracetamol", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "1000 mg three or four times daily, maximum 4000 mg in 24 hours", "adult_duration": "while the pelvic pain lasts, reviewed at the 72-hour follow-up", "dose_source": "MSF Essential Drugs 2024 - paracetamol (oral)", "rationale": "BASHH puts analgesia in General Advice, before the antibiotic regimens, and the woman came in with pain. The guideline says 'appropriate analgesia' without naming a drug, so the drug and dose come from the label.", "cautions": [ "First choice for the pain here - no stomach or renal risk and it does not interact with the antibiotics.", "Check every other product she is taking for paracetamol. Cold and flu sachets are the usual way an accidental overdose happens.", "Reduce the maximum to 3000 mg/day if she is under 50 kg, malnourished, or has liver disease.", "Pain that is not settling by 72 hours is a reason to reassess for tubo-ovarian abscess, not a reason to add more analgesia.", "500 mg is the per-dose ceiling used here for a child. 1000 mg is the adult dose and does not belong in a weight calculation - the daily 60 mg/kg limit is the one that binds first in any case." ], "peds_mgkg_low": 15.0, "peds_mgkg_high": 15.0, "peds_max_mg": 500.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "15 mg/kg 3 or 4 times daily, maximum 60 mg/kg daily. The PID guideline itself is aimed at women aged 16 and over; anyone younger goes down a different pathway. Under 1 month: 10 mg/kg 3 or 4 times daily, maximum 40 mg/kg/day (MSF Essential Drugs 2024).", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 150, "high_mg": 150, "capped": false }, { "weight_kg": 20, "low_mg": 300, "high_mg": 300, "capped": false }, { "weight_kg": 30, "low_mg": 450, "high_mg": 450, "capped": false }, { "weight_kg": 40, "low_mg": 500, "high_mg": 500, "capped": true } ], "brands": [ { "trade_name": "FEBRIMOL 500 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 3.5, "pack_count": 20, "unit_price": 0.17, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETAMOL 500 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 8.0, "pack_count": 20, "unit_price": 0.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PARACETAMOL-MUP 500MG B.P. 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 13.0, "pack_count": 20, "unit_price": 0.65, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETAL 500 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 24.0, "pack_count": 20, "unit_price": 1.2, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ARKADOLOW 500 MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UTOPIA", "price_egp": 42.0, "pack_count": 30, "unit_price": 1.4, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PARAMOL 500MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 38.0, "pack_count": 20, "unit_price": 1.9, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ADOL 500MG 24 CAPLETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AUGICETAMIDE 500 MG 20 SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AUG PHARMA", "price_egp": 50.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FEBRIMOL ORAL DROPS 20 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "THERA-LO 3.2G/100ML ORAL SUSP. 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 3200.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" }, { "id": 1409, "generic": "Ibuprofen", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 400.0, "adult_dose": "400 mg up to three times daily with or after food, maximum 1200 mg in 24 hours", "adult_duration": "while the pelvic pain lasts, reviewed at the 72-hour follow-up", "dose_source": "Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560)", "rationale": "The pain of PID is inflammatory and an NSAID suits it better than paracetamol alone. BASHH says 'appropriate analgesia' without naming a drug; the dose is the label's.", "cautions": [ "Not if she is or might be pregnant - and pregnancy must be excluded in every suspected PID anyway, because the differential is ectopic.", "Avoid in asthma, active peptic ulcer and renal impairment.", "With food, and not on top of another NSAID.", "Can be given with the paracetamol rather than instead of it if the pain is severe." ], "peds_mgkg_low": 20.0, "peds_mgkg_high": 20.0, "peds_max_mg": 1200.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "20 mg/kg/day in divided doses, three to four times daily with food. Not under 3 months. The PID guideline is aimed at women aged 16 and over.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 200, "high_mg": 200, "capped": false }, { "weight_kg": 20, "low_mg": 400, "high_mg": 400, "capped": false }, { "weight_kg": 30, "low_mg": 600, "high_mg": 600, "capped": false }, { "weight_kg": 40, "low_mg": 800, "high_mg": 800, "capped": false } ], "brands": [ { "trade_name": "DAJUANOFEN 400 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "COPAD PHARMA", "price_egp": 5.0, "pack_count": 20, "unit_price": 0.25, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLABU 400MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA PHARMA", "price_egp": 3.75, "pack_count": 10, "unit_price": 0.38, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVA-PROFEN 400MG 30 F.C. TABLETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 12.75, "pack_count": 30, "unit_price": 0.42, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "IBUPROFEN 400 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 6.0, "pack_count": 10, "unit_price": 0.6, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MAFO 400 MG 30 F.C.TABS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 42.0, "pack_count": 30, "unit_price": 1.4, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEN 400 MG 30 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA > ABBOTT LABORATORIES", "price_egp": 78.0, "pack_count": 30, "unit_price": 2.6, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PROFUSOL 400MG 20 S.G CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 31.0, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ANALGIPROF 400 MG 25 SACHETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 37.5, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NOVA-PROFEN 100MG/5ML ORAL SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 2.25, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "BRUFEMOL-N SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 4.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pelvic-inflammatory-disease" } ] }