{ "schema_version": 1, "kind": "condition", "id": "pediatric-asthma-acute-exacerbation", "name": "Mild-to-Moderate Acute Asthma Exacerbation in Children", "category": "chronic", "sources": "GINA Strategy for Asthma Management and Prevention 2023", "review_status": "reviewed", "verified_against": "GINA Strategy for Asthma Management and Prevention 2023 ยท Mild-to-Moderate Acute Asthma Exacerbation in Children - disease-level clinical article (pediatric-asthma-acute-exacerbation-full.txt)", "verified_date": "2026-08", "treatments": [ { "id": 1393, "generic": "Salbutamol", "line": 1, "is_adjunct": false, "form": "oral.inhalation", "strength_mg": 0.1, "adult_dose": "Not applicable - pediatric condition", "adult_duration": "1-3 days during acute flare", "dose_source": "GINA Strategy for Asthma Management and Prevention 2023", "rationale": "Inhaled short-acting beta-2 agonist (SABA) via pressurisd metered-dose inhaler (pMDI) with spacer is equal or superior to nebulizer", "cautions": [ "ALWAYS USE SPACER: pMDI + spacer is as effective as nebulizer and reduces systemic side effects.", "If child requires >6 puffs every 4 hours or shows red flags (silent chest, cyanosis, intercostal retraction, inability to talk), TRANSFER URGENTLY TO HOSPITAL.", "Tachycardia and fine tremor are common transient beta-2 agonist side effects." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children <6 years: 2-6 puffs via spacer + face mask every 20 mins for 1 hour; Children >=6 years: 4-10 puffs via spacer every 20 mins for 1 hour", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Under 6 years", "age_min_months": 0, "age_max_months": 71, "dose_text": "2 to 6 puffs via spacer with face mask, every 20 minutes for 1 hour" }, { "label": "6 years and over", "age_min_months": 72, "age_max_months": 216, "dose_text": "4 to 10 puffs via spacer, every 20 minutes for 1 hour" } ], "peds_doses": null, "brands": [ { "trade_name": "AEROLIN 100MCG/DOSE INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO > 3M HEALTH CARE-U.K.", "price_egp": 7.3, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BUTALIN 100MCG/ACTUATION 200 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VENTAL INHALER 100 MCG/DOSE 200 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 72.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VIASALMOL 100MCG 200 ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MDI PHARMA", "price_egp": 72.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VENTOLIN EVOHALER 100MCG/ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 86.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPICHESTAL SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 2.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "SALBUTAMOL 2MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 3.5, "pack_count": null, "unit_price": null, "strength_mg": 2.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pediatric-asthma-acute-exacerbation" }, { "id": 1395, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Mild-to-Moderate Acute Asthma Exacerbation in Children - disease-level clinical article (pediatric-asthma-acute-exacerbation-full.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - The signs of impending respiratory failure and arrest are altered mental status, lethargy, cyanosis, and a silent chest." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "pediatric-asthma-acute-exacerbation" }, { "id": 1394, "generic": "Prednisolone", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 5.0, "adult_dose": "Not applicable - pediatric condition", "adult_duration": "3-5 days", "dose_source": "GINA Strategy for Asthma Management and Prevention 2023", "rationale": "Prednisolone is an oral corticosteroid added to bronchodilator therapy during an acute asthma exacerbation to reduce airway inflammation and speed recovery; it is a short adjunct course, not maintenance therapy.", "cautions": [ "Short course (3-5 days) does NOT require tapering.", "Give with food in the morning to prevent GI distress and insomnia.", "Re-evaluate baseline controller therapy (ICS) post-exacerbation." ], "peds_mgkg_low": 1.0, "peds_mgkg_high": 2.0, "peds_max_mg": 40.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "1-2 mg/kg once daily in the morning (max 20 mg for <2 yrs, 30 mg for 2-5 yrs, 40 mg for >5 yrs) for 3-5 days", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Under 2 years", "age_min_months": 0, "age_max_months": 23, "dose_text": "1 to 2 mg/kg once daily in the morning, maximum 20 mg, for 3 to 5 days" }, { "label": "2 to 5 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "1 to 2 mg/kg once daily in the morning, maximum 30 mg, for 3 to 5 days" }, { "label": "Over 5 years", "age_min_months": 72, "age_max_months": 216, "dose_text": "1 to 2 mg/kg once daily in the morning, maximum 40 mg, for 3 to 5 days" } ], "peds_doses": [ { "weight_kg": 10, "low_mg": 10, "high_mg": 20, "capped": false }, { "weight_kg": 20, "low_mg": 20, "high_mg": 40, "capped": false }, { "weight_kg": 30, "low_mg": 30, "high_mg": 40, "capped": true }, { "weight_kg": 40, "low_mg": 40, "high_mg": 40, "capped": true } ], "brands": [ { "trade_name": "HOSTACORTIN H 5MG 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 12.0, "pack_count": 30, "unit_price": 0.4, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE 5 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 24.0, "pack_count": 20, "unit_price": 1.2, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDILONE 5MG 10 TAB. (25 STRIPS PACK)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 250.0, "pack_count": 10, "unit_price": 25.0, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPICOPRED 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 69.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE-EVA 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 79.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DISPRELONE-OD 5 MG 30 ORODISPERSABLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ANDALOUS PHARMA", "price_egp": 84.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SOLUPRED ORO 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI WINTHROP > SANOFI", "price_egp": 84.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ACETASEE 1% EYE DROPS (SUSP.) 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNIS 5MG/5ML SYRUP 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 9.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "pediatric-asthma-acute-exacerbation" } ] }