{
  "schema_version": 1,
  "kind": "condition",
  "id": "paronychia",
  "name": "Acute Paronychia",
  "category": "infectious",
  "sources": "NICE Clinical Knowledge Summaries: Paronychia - acute 2021 · Egyptian National Drug Formulary - Antimicrobial 2023 (fusidic acid monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (amoxicillin and clavulanate monograph) · No labelled dose - a procedure, not a medicine · Paronychia - StatPearls - NCBI Bookshelf (NBK544307); duration and paediatric dose from Cephalexin US label, SetID 0a24b6e5-6f13-44b4-93f4-47c86945cad2, section 2",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 (fusidic acid monograph) · Egyptian National Drug Formulary - Antimicrobial 2023 (amoxicillin and clavulanate monograph) · No labelled dose - a procedure, not a medicine · Acute Paronychia - disease-level clinical article (paronychia-full.txt) · Acute Paronychia - disease-level clinical article (paronychia-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1385,
      "generic": "Warm water soak and local care",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "Soak affected digit in warm water for 15-20 minutes three to four times daily",
      "adult_duration": "7 days or until resolved",
      "dose_source": "No labelled dose - a procedure, not a medicine",
      "rationale": "Warm water soaks are a non-drug measure that softens the skin and encourages the paronychia to drain spontaneously, and form the mainstay of care for early, non-fluctuant infection.",
      "cautions": [
        "Do not attempt home drainage with non-sterile instruments.",
        "Seek urgent evaluation if red streaks extend up finger/toe (lymphangitis) or fever develops."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Soak affected digit in warm water 3-4 times daily under adult supervision",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "paronychia"
    },
    {
      "id": 1386,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Paronychia - disease-level clinical article (paronychia-full.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "RED FLAG - Refer to a hand surgeon when infection spreads to underlying tendons or is severe (debridement/washout/amputation may be needed).",
        "RED FLAG - Follow-up requirement within 24-48 hours after drainage to check for worsening infection is not mentioned"
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "paronychia"
    },
    {
      "id": 1384,
      "generic": "Amoxicillin + Clavulanic acid",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 625.0,
      "adult_dose": "625 mg (500/125) three times daily or 1000 mg (875/125) twice daily",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (amoxicillin and clavulanate monograph)",
      "rationale": "Amoxicillin-clavulanate is an oral antibiotic covering staphylococci and anaerobes, used when paronychia is more extensive or fails topical therapy; incision and drainage of any fluctuant abscess remains essential alongside it.",
      "cautions": [
        "Contraindicated in history of penicillin anaphylaxis or amoxicillin/clavulanate-associated jaundice.",
        "Incision and drainage of fluctuant abscess remains essential alongside antibiotics.",
        "Reduce dose in severe renal impairment."
      ],
      "peds_mgkg_low": 25.0,
      "peds_mgkg_high": 45.0,
      "peds_max_mg": 1750.0,
      "peds_basis": "day",
      "peds_unit": "mg",
      "peds_note": "25-45 mg/kg/day (based on amoxicillin component) divided twice daily for 7 days",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 250,
          "high_mg": 450,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 500,
          "high_mg": 900,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 750,
          "high_mg": 1350,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 1000,
          "high_mg": 1750,
          "capped": true
        }
      ],
      "brands": [
        {
          "trade_name": "AUJED 625 MG 12 F.C. TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA TEC > JEDCO INT. CO. FOR PHARMACEUTICALS",
          "price_egp": 19.2,
          "pack_count": 12,
          "unit_price": 1.6,
          "strength_mg": 625.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "E-MOXCLAV 625MG 10 TAB.",
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          "manufacturer": "EIPICO",
          "price_egp": 30.0,
          "pack_count": 10,
          "unit_price": 3.0,
          "strength_mg": 625.0,
          "exact_strength": true,
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          "discontinued": false,
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        },
        {
          "trade_name": "DEXICLAVE 625 MG 12 F.C. TABS.",
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          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > NOVELL PHARMA",
          "price_egp": 37.5,
          "pack_count": 12,
          "unit_price": 3.12,
          "strength_mg": 625.0,
          "exact_strength": true,
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          "trade_name": "MAGNABIOTIC 625MG 8 TAB.",
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          "strength_mg": 625.0,
          "exact_strength": true,
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        {
          "trade_name": "CLAVIMOX 625 MG 12 F.C.TABS.",
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          "strength_mg": 625.0,
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          "trade_name": "CURAM 625MG 12 F.C.TAB.",
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          "manufacturer": "SANDOZ > NOVARTIS",
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          "strength_mg": 625.0,
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        {
          "trade_name": "AUGMENTIN 625 MG 10 F.C.TABS.",
          "scientific_name": null,
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          "manufacturer": "MUP > SMITHKLINE BEECHAM",
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          "pack_count": 10,
          "unit_price": 11.7,
          "strength_mg": 625.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CLAVOCILLIN 625 MG 10 DISPERSIBLE TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "RAMEDA > ORGANOPHARMA",
          "price_egp": 31.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 625.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LARYNCLAVE 125/31 PD. FOR ORAL SUSP. 70ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR > AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
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        },
        {
          "trade_name": "MEGACLAVOX 156MG/5ML PD. FOR SUSP. 60 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 8.0,
          "pack_count": null,
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          "strength_mg": 156.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "paronychia"
    },
    {
      "id": 1387,
      "generic": "Clindamycin",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 300.0,
      "adult_dose": "Oral: 300–450 mg every 6 hours.",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023",
      "rationale": "Oral lincosamide antibiotic providing anti-staphylococcal coverage for acute paronychia.",
      "cautions": [
        "Hypersensitivity to clindamycin, lincomycin, or any component of the formulation.",
        "High risk of Clostridioides difficile-associated diarrhea (CDAD); discontinue if significant diarrhea occurs."
      ],
      "peds_mgkg_low": 20.0,
      "peds_mgkg_high": 40.0,
      "peds_max_mg": 1800.0,
      "peds_basis": "day",
      "peds_unit": "mg",
      "peds_note": "Oral: Infants, Children, and Adolescents: 8 to 20 mg/kg/day divided every 6 to 8 hours (or 20 to 40 mg/kg/day for severe infections, max 1800 mg daily).",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 200,
          "high_mg": 400,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 400,
          "high_mg": 800,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 600,
          "high_mg": 1200,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 800,
          "high_mg": 1600,
          "capped": false
        }
      ],
      "brands": [
        {
          "trade_name": "ADCOCLINDACE 300 MG 16 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 24.0,
          "pack_count": 16,
          "unit_price": 1.5,
          "strength_mg": 300.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
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        },
        {
          "trade_name": "CLINACYN 300MG 16 CAPS.",
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          "normalized_ingredient": null,
          "manufacturer": "SIGMA > EGYPTIAN PHARMACISTS COMPANY",
          "price_egp": 31.5,
          "pack_count": 16,
          "unit_price": 1.97,
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          "exact_strength": true,
          "exact_form": true,
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        },
        {
          "trade_name": "CLINDAM 300 MG 16 CAPS.",
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          "manufacturer": "SIGMA > OCTOBER PHARMA",
          "price_egp": 75.0,
          "pack_count": 16,
          "unit_price": 4.69,
          "strength_mg": 300.0,
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        {
          "trade_name": "MEPACLIND 300MG 8 CAPS.",
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          "manufacturer": "MEPACO",
          "price_egp": 38.0,
          "pack_count": 8,
          "unit_price": 4.75,
          "strength_mg": 300.0,
          "exact_strength": true,
          "exact_form": true,
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        },
        {
          "trade_name": "CLINDACINE ART 300 MG 12 CAPS.",
          "scientific_name": null,
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          "manufacturer": "RAMEDA > ART PHARMA",
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          "pack_count": 12,
          "unit_price": 6.33,
          "strength_mg": 300.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ALFACLINDAMYCIN 300 MG 10 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ATCO PHARMA > ROTABIOGEN",
          "price_egp": 69.0,
          "pack_count": 10,
          "unit_price": 6.9,
          "strength_mg": 300.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DALACIN C 300MG 10 CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PFIZER",
          "price_egp": 114.0,
          "pack_count": 10,
          "unit_price": 11.4,
          "strength_mg": 300.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "KLENDABIOTICAM 1 % TOP. SOLUTION",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PANAX PHARMA",
          "price_egp": 8.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ADCOCLINDACE 10MG/ML TOP. SOL.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 12.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "paronychia"
    },
    {
      "id": 1388,
      "generic": "Cefalexin",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "500 mg three to four times a day",
      "adult_duration": "7 to 14 days",
      "dose_source": "Paronychia - StatPearls - NCBI Bookshelf (NBK544307); duration and paediatric dose from Cephalexin US label, SetID 0a24b6e5-6f13-44b4-93f4-47c86945cad2, section 2; paediatric ceiling from Egyptian National Drug Formulary - Antimicrobial 2023 (cephalexin monograph)",
      "rationale": "Acute paronychia is a staphylococcal infection, so the article's oral choice after failed topical treatment is a plain anti-staphylococcal agent. The card jumps straight to co-amoxiclav and clindamycin, which are the choices for suspected oral inoculation or anaerobic cover, not for the ordinary case.",
      "cautions": [
        "Do not use it in anyone with known hypersensitivity to cephalexin or any other cephalosporin.",
        "It has no anaerobic cover - if the paronychia may have been seeded from the mouth, or the patient has MRSA risk factors, this is the wrong row."
      ],
      "peds_mgkg_low": 25.0,
      "peds_mgkg_high": 50.0,
      "peds_max_mg": 2000.0,
      "peds_basis": "day",
      "peds_unit": "mg",
      "peds_note": "Children: a total of 25 to 50 mg/kg a day in divided doses for 7 to 14 days. Maximum 2,000 mg a day (Egyptian National Drug Formulary - Antimicrobial 2023, cephalexin monograph).",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 250,
          "high_mg": 500,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 500,
          "high_mg": 1000,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 750,
          "high_mg": 1500,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 1000,
          "high_mg": 2000,
          "capped": false
        }
      ],
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        {
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          "manufacturer": "ARAB CAPS > PHAROPHARMA",
          "price_egp": 9.0,
          "pack_count": 12,
          "unit_price": 0.75,
          "strength_mg": 500.0,
          "exact_strength": true,
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        },
        {
          "trade_name": "CEPHALEXCID 500 MG 12 CAPS.",
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          "manufacturer": "CID",
          "price_egp": 10.3,
          "pack_count": 12,
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        {
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          "unit_price": 0.88,
          "strength_mg": 500.0,
          "exact_strength": true,
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          "trade_name": "MEDICEFLEXIN 500 MG 20 CAPS.",
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          "manufacturer": "T3A PHARMA > RIVA PHARMA S.A.E.",
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        {
          "trade_name": "CEPHALEXIN 500MG 12 CAPS B.P.2007",
          "scientific_name": null,
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          "manufacturer": "SHIFA MEDICAL PRODUCTS > OCTOBER PHARMA",
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          "unit_price": 2.25,
          "strength_mg": 500.0,
          "exact_strength": true,
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        {
          "trade_name": "KEFLEX 500 MG 12 CAPS.",
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          "manufacturer": "HIKMA PHARMA",
          "price_egp": 58.0,
          "pack_count": 12,
          "unit_price": 4.83,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
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        },
        {
          "trade_name": "CEPOREX 500MG 12 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLAXO SMITHKLINE",
          "price_egp": 69.0,
          "pack_count": 12,
          "unit_price": 5.75,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
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        },
        {
          "trade_name": "AMTHROST 125MG/5ML SUSP. 60ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA > SABAA",
          "price_egp": 4.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 125.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
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        },
        {
          "trade_name": "AMTHROST 250MG/5ML SUSP. 60ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA > SABAA",
          "price_egp": 4.5,
          "pack_count": null,
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          "strength_mg": 250.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
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        }
      ],
      "condition_id": "paronychia"
    },
    {
      "id": 1383,
      "generic": "Fusidic acid",
      "line": 1,
      "is_adjunct": true,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 2% ointment or cream to affected nail fold two to three times daily after warm water soak",
      "adult_duration": "7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (fusidic acid monograph)",
      "rationale": "Fusidic acid is a topical antibiotic active against the Staphylococcus aureus that usually causes acute paronychia; it is used alongside warm soaks and drainage of any abscess, not as a substitute for drainage.",
      "cautions": [
        "Perform incision and drainage if a fluctuant abscess is present.",
        "Avoid biting nails or picking cuticles.",
        "If infection spreads or fails to resolve within 7 days, initiate oral antibiotics."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Apply 2% cream or ointment 2 to 3 times daily for 7 to 14 days.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
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