# Otitis Media with Effusion (Glue ear)

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Otitis Media With Effusion - StatPearls (NCBI Bookshelf NBK538293) - https://www.ncbi.nlm.nih.gov/books/NBK538293/: "For most children diagnosed with OME, conservative treatment with watchful waiting is recommended within the first 3 months of diagnosis." and "Autoinsufflation involves forcing air from the nose and throat into the middle ear to equalize pressure and promote drainage." · No labelled dose - isotonic saline irrigation, used as often as it helps
- Verified date: 2026-08

## Verified against

- Otitis Media With Effusion - StatPearls (NCBI Bookshelf NBK538293) - https://www.ncbi.nlm.nih.gov/books/NBK538293/: "For most children diagnosed with OME, conservative treatment with watchful waiting is recommended within the first 3 months of diagnosis." and "Autoinsufflation involves forcing air from the nose and throat into the middle ear to equalize pressure and promote drainage."
- No labelled dose - isotonic saline irrigation, used as often as it helps
- Otitis Media with Effusion (Glue ear) - disease-level clinical article (otitis-media-with-effusion-full.txt)

## Treatment metadata

- No drug therapy in primary care (Active Observation & Autoinflation)
- Sodium chloride — nasal

## Complete treatment card

```text
OTITIS MEDIA WITH EFFUSION (GLUE EAR)
Sources: Otitis Media With Effusion - StatPearls (NCBI Bookshelf NBK538293) -
         https://www.ncbi.nlm.nih.gov/books/NBK538293/: "For most children diagnosed with OME,
         conservative treatment with watchful waiting is recommended within the first 3 months of
         diagnosis." and "Autoinsufflation involves forcing air from the nose and throat into the
         middle ear to equalize pressure and promote drainage." · No labelled dose - isotonic saline
         irrigation, used as often as it helps
Review status: REVIEWED against Otitis Media With Effusion - StatPearls (NCBI Bookshelf NBK538293) -
               https://www.ncbi.nlm.nih.gov/books/NBK538293/: "For most children
               diagnosed with OME, conservative treatment with watchful waiting is
               recommended within the first 3 months of diagnosis." and
               "Autoinsufflation involves forcing air from the nose and throat into
               the middle ear to equalize pressure and promote drainage.", No
               labelled dose - isotonic saline irrigation, used as often as it
               helps, Otitis Media with Effusion (Glue ear) - disease-level
               clinical article (otitis-media-with-effusion-full.txt)  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (4)
    - Hearing loss is the symptom patients and families report most often  [hearing loss]
    - Can bring communication delays, academic struggles, behavioral or sleep problems, and social
      withdrawal in children  [social withdrawal]
    - In adults the effusion is usually one-sided and follows an upper respiratory infection, with
      hearing loss, tinnitus, or ear fullness  [hearing loss · tinnitus]
    - Adult fluid buildup often follows pressure changes from flying or diving
  SIGNS - what you find (2)
    - Reduced eardrum mobility and light reflex on pneumatic otoscopy support the diagnosis
    - The eardrum may show air bubbles, a fluid film, cloudiness, or a bluish or yellowish tinge
  TESTS (6)
    - A flat tympanogram supports the diagnosis
    - ABR confirms hearing loss in infants who fail newborn screening but misses the conductive loss
      caused by effusion
    - OAE screening lacks specificity and can be thrown off by background noise
    - Conductive loss from OME can produce an air-bone gap greater than 15 dB HL
    - CT can rule out cholesteatoma or other middle ear disease, and extracranial, intracranial, or
      congenital anomalies
    - Tympanocentesis, performed in the office, can serve both a diagnostic culture role and a
      therapeutic role
  IF NOT THIS - what else fits (8)
    - Benign nasopharyngeal masses are on the adult differential
    - Malignant tumors of the nasal cavity should be considered in adults with OME
    - Malignant tumors of the temporal bone are on the adult differential
    - Nasopharyngeal carcinoma is a differential to exclude, especially with unilateral adult
      effusion
    - Patulous Eustachian tube is on the adult differential list
    - Congenital craniofacial anomalies are on the pediatric differential
    - IgG subclass deficiencies are on the pediatric differential
    - Acute otitis media is a key differential in children
  Source  StatPearls "Otitis Media With Effusion" - disease-level clinical article
  Status  traced to the source above

1. NO DRUG THERAPY IN PRIMARY CARE (ACTIVE OBSERVATION & AUTOINFLATION)[1st line]
   Adult    Active observation for 3 months, then reassess hearing. Consider autoinflation (blowing
            up a balloon through the nostril) in a child old enough to engage with it. Refer for
            formal hearing assessment when OME is clinically suspected. x 3 months, then reassess
   Peds     Reassess hearing after 3 months in bilateral OME with hearing loss. In children who are
            experiencing hearing difficulties that significantly affect day-to-day living, consider
            intervening earlier than the 3-month reassessment.
   Source   Otitis Media With Effusion - StatPearls (NCBI Bookshelf NBK538293) -
            https://www.ncbi.nlm.nih.gov/books/NBK538293/: "For most children diagnosed with OME,
            conservative treatment with watchful waiting is recommended within the first 3 months of
            diagnosis." and "Autoinsufflation involves forcing air from the nose and throat into the
            middle ear to equalize pressure and promote drainage."
   Why      Most glue ear resolves on its own. NG233 replaced CG60 in 2023 and offers no medicine
            for it - the treatment is time, a hearing test, and referral if it does not settle.
   Caution  Do NOT offer antibiotics for OME (NG233 1.5.2).
            Do NOT offer oral or nasal corticosteroids for OME or the hearing loss it causes (NG233
            1.5.3).
            Do NOT offer antihistamines, montelukast, mucolytics, PPIs or anti-reflux drugs, or
            decongestants (NG233 1.5.4).
            Persistent hearing loss past 3 months needs audiometry and ENT assessment - grommets are
            decided there, not here.
            RED FLAG - An adult with OME on one side only is not a candidate for watchful waiting.
            Examine the head and neck properly, with nasopharyngoscopy and, where indicated, imaging
            - the question being malignancy (nasopharyngeal carcinoma above all) or other disease of
            the nose and nasopharynx.

2. SODIUM CHLORIDE                                        [add-on - not a substitute]
   Adult    Instil 1-2 sprays of 0.9% nasal saline spray into each nostril 3-4 times daily - As
            needed for nasal comfort
   Peds     1-2 drops/sprays into each nostril before feeds or bedtime
   Source   No labelled dose - isotonic saline irrigation, used as often as it helps
   Why      Salt water for a blocked nose, nothing more. It does not clear the fluid behind the
            eardrum and does not shorten glue ear - NICE lists no medical treatment that does.
   Caution  This treats a blocked nose, not the effusion. Do not let it stand in for the hearing
            reassessment at 3 months.
            Saline has no licensed dose - it is salt water. Use it as often as it clears the nose.
   Egypt    SOFIMER 0.9% MINI ISOTONIC NASAL SPRAY 30 ML > SOFICOPHARM                    170.00 EGP
            SOFIMER 0.9% ISOTONIC NASAL SPRAY 100 ML > SOFICOPHARM                        290.00 EGP
            POLYMER BABY ISOTONIC 0.9% NASAL SPRAY 100ML UK MEDICA LIMITED > WALFARM      300.00 EGP
            SODIUM CHLORIDE 0.9% (EL NASR) IRRIGAATION SOLN. 3000 ML EL NASR               22.50 EGP
            PHYSIOMER NORMAL JET NASAL SPRAY 135ML LABORATOIRE DE LA MER > STAR INTE...   300.00 EGP
            PHYSIOMER BABY MIST NASAL SPRAY 115ML LABORATOIRE DE LA MER > STAR INTER...   400.00 EGP
            UNIMER BABY 9% NASAL SOLUTION UNITDOSE 12*5ML LDPSA > WALFARM                  54.00 EGP
            UNIMER BABY 9% NASAL SOLUTION UNITDOSE 50*5ML LDPSA > WALFARM                 150.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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