{ "schema_version": 1, "kind": "condition", "id": "ophthalmia-neonatorum", "name": "Ophthalmia neonatorum (newborn conjunctivitis)", "category": "infectious", "sources": "StatPearls: Ophthalmia Neonatorum (NCBI Bookshelf NBK551572) · Egyptian National Drug Formulary, antimicrobial 2023, ceftriaxone monograph (printed p. 247) · No labelled dose - a procedure, not a medicine · Ophthalmia neonatorum - disease-level clinical article (ophthalmia-neonatorum-full.txt), Maternal and partner therapy, corroborated by Egyptian National Drug Formulary - Antimicrobial 2023 (azithromycin monograph, Dosage Regimen, Sexually transmitted infections)", "review_status": "reviewed", "verified_against": "StatPearls: Ophthalmia Neonatorum (NCBI Bookshelf NBK551572) · No labelled dose - a procedure, not a medicine · Ophthalmia Neonatorum - disease-level clinical article (ophthalmia-neonatorum-clinical.txt) · Egyptian National Drug Formulary - Antimicrobial 2023 (cefotaxime monograph, neonatal dosage) · Ophthalmia neonatorum - disease-level clinical article (ophthalmia-neonatorum-full.txt) · Ophthalmia neonatorum - disease-level clinical article (ophthalmia-neonatorum-full.txt), Maternal and partner therapy, corroborated by Egyptian National Drug Formulary - Antimicrobial 2023 (azithromycin monograph, Dosage Regimen, Sexually transmitted infections)", "verified_date": "2026-08", "treatments": [ { "id": 1289, "generic": "Ceftriaxone", "line": 1, "is_adjunct": false, "form": "injection", "strength_mg": null, "adult_dose": "Not applicable - a disease of the first month of life", "adult_duration": "Single dose", "dose_source": "StatPearls: Ophthalmia Neonatorum (NCBI Bookshelf NBK551572)", "rationale": "For gonococcal disease, which is the one that blinds. Purulent discharge with marked lid swelling in the first five days is gonococcal until proved otherwise, and it does not wait for a swab result.", "cautions": [ "Untreated gonococcal infection ulcerates and perforates the cornea, and it can do it within 24 to 48 hours of the discharge starting. This is a same-day referral, not a next-appointment one.", "NOT in a jaundiced newborn, and above all not a premature one: ceftriaxone displaces bilirubin from albumin. In a baby who is both jaundiced and infected, an alternative cephalosporin is needed and that choice belongs to whoever is admitting the child.", "Never alongside any intravenous calcium-containing fluid in a baby of 28 days or less. That combination has killed neonates.", "Do not give ceftriaxone intravenously in a solution containing lidocaine.", "Treat the mother and her partner. A newborn's gonococcal eye is a maternal genital infection that has not been dealt with, and without treating it the next baby gets the same thing." ], "peds_mgkg_low": 25.0, "peds_mgkg_high": 50.0, "peds_max_mg": 125.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "25-50 mg/kg as a single intramuscular dose, never more than 125 mg.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 125, "high_mg": 125, "capped": true }, { "weight_kg": 20, "low_mg": 125, "high_mg": 125, "capped": true }, { "weight_kg": 30, "low_mg": 125, "high_mg": 125, "capped": true }, { "weight_kg": 40, "low_mg": 125, "high_mg": 125, "capped": true } ], "brands": [ { "trade_name": "CEFAXONE 250MG I.V. VIAL.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO B", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFOTRIX 250MG I.V.VIAL (U.S.P.23)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIXOMASH 500MG VIAL FOR I.V. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > MASH PREMIERE", "price_egp": 16.5, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 500MG VIAL FOR I.M. INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 36.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "WINTRIAXONE 1 GM PD. FOR I.M INJ.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFTRIAXONE-SANDOZ 500 MG I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO B > SANDOZ", "price_egp": 62.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.M. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRIAXONE 1 GM I.V VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > TABUK PHARMA", "price_egp": 106.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" }, { "id": 1290, "generic": "Azithromycin", "line": 1, "is_adjunct": false, "form": "oral.liquid", "strength_mg": null, "adult_dose": "Not applicable - a disease of the first month of life", "adult_duration": "Single dose, repeated after one week", "dose_source": "StatPearls: Ophthalmia Neonatorum (NCBI Bookshelf NBK551572)", "rationale": "For chlamydial disease, the commoner cause and the later one - typically the second week, with less dramatic swelling. Ceftriaxone does not cover chlamydia at all, so a gonococcal dose alone leaves it untreated.", "cautions": [ "Chlamydia is not covered by ceftriaxone - the formulary says so explicitly. If both are possible, both need treating.", "Chlamydial conjunctivitis in a newborn means chlamydial pneumonia may follow weeks later. Warn the parents what a persistent staccato cough at 4 to 12 weeks means.", "Oral erythromycin in the first weeks of life is associated with pyloric stenosis - a reason to prefer the azithromycin regimen where there is a choice.", "The mother and her sexual partner need treating too, or the baby is reinfected - the article is firm that covering them at the same time is what stops it coming back, and gives her azithromycin 1 g by mouth. Their dose is the one listed under Mother and sexual partner - the newborn is dosed separately and must NOT be given it." ], "peds_mgkg_low": 20.0, "peds_mgkg_high": 20.0, "peds_max_mg": null, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "20 mg/kg by mouth as a single dose, repeated once a week later. Erythromycin 50 mg/kg/day in 4 divided doses for 14 days is the alternative.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 200, "high_mg": 200, "capped": false }, { "weight_kg": 20, "low_mg": 400, "high_mg": 400, "capped": false }, { "weight_kg": 30, "low_mg": 600, "high_mg": 600, "capped": false }, { "weight_kg": 40, "low_mg": 800, "high_mg": 800, "capped": false } ], "brands": [ { "trade_name": "ZITHRODOSE 100MG/5ML SUSP. 15ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR > AVERROES PHARMA-EGYPT", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHROPHATE 200MG/5ML SUSP. 15ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORGANO PHARMA > NOVELL PHARMA", "price_egp": 12.75, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AZATRIBACT 200MG/5ML SUSP. 22.5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RIVA PHARMA S.A.E.", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AZI-ONCE 200MG/5ML SUSP. 22.5ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JAMJOOM PHARMACEUTICALS", "price_egp": 34.0, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AZITHROTREAT 2GM/60ML PD. FOR ORAL SUSP.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > ANDALOUS PHARMA", "price_egp": 44.0, "pack_count": null, "unit_price": null, "strength_mg": 2000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHRODOSE 100MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR > AVERROES PHARMA-EGYPT", "price_egp": 62.0, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHROMAX 900MG/22.5ML (200MG/5ML) SUSP.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 100.0, "pack_count": null, "unit_price": null, "strength_mg": 900.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHROMAX 1200MG/30ML (200MG/5ML) SUSP.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 126.0, "pack_count": null, "unit_price": null, "strength_mg": 1200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AZOMYCIN 200MG/5ML SUSP. 15ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 15.6, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "GIGAZOCIN 200MG/5ML PD. ORAL SUSP. 25 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "T3A PHARMA > PIONEER", "price_egp": 16.5, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" }, { "id": 1292, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": null, "adult_duration": null, "dose_source": "Ophthalmia Neonatorum - disease-level clinical article (ophthalmia-neonatorum-clinical.txt)", "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.", "cautions": [ "RED FLAG - Gonococcal ophthalmia neonatorum requires hospitalization due to risk of systemic dissemination (arthritis, meningitis, sepsis).", "RED FLAG - Urgent ophthalmology referral is required when corneal involvement, pseudomembranes, or any threat to vision is identified." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": null, "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "ophthalmia-neonatorum" }, { "id": 1294, "generic": "Erythromycin", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "0.5% ointment applied to both eyes within the first hour after birth", "adult_duration": null, "dose_source": "Ophthalmia neonatorum (newborn conjunctivitis) - disease-level clinical article (ophthalmia-neonatorum-clinical.txt)", "rationale": "Universal ocular prophylaxis at birth to prevent gonococcal and chlamydial ophthalmia neonatorum.", "cautions": [ "None of the three prophylaxis agents the source names can be bought in Egypt. Erythromycin 0.5% eye ointment has no Egyptian product of any kind, plain tetracycline 1% eye ointment has none, and povidone-iodine 2.5% ophthalmic solution has none - the only povidone eye products here are lubricants, not the antiseptic.", "The nearest thing a pharmacy will hand over is oxytetracycline with polymyxin B eye ointment. It is a different tetracycline at half the strength the source specifies, so it is a substitution to make deliberately and not the sourced regimen.", "Where prophylaxis cannot be given, what protects the baby is treating the mother's infection in pregnancy and treating a symptomatic newborn at once with ceftriaxone or azithromycin.", "Purulent discharge in the first days of life is gonococcal until proven otherwise and is a same-day sight-threatening emergency. Prophylaxis given at birth does not rule it out." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Applied to both eyes within the first hour after birth.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "AKNEMYCIN 2% OINT. 15 GM (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > HERMAL-GERMANY", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ACNI-CARE 2% TOP. GEL. 20 GM (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 6.5, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ERYTHROCID 200 MG/5ML SUSP. 60ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 5.6, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ERYTHROMYCIN PHARCO 200MG/5ML SUSP. 60ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "AKNEMYCIN 2% SOLUTION 25 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP > HERMAL-GERMANY", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ETHYRONATE 200MG/5ML SUSP. 100 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 9.5, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ETHYRONATE 400MG/5ML SUSP. 100 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 11.75, "pack_count": null, "unit_price": null, "strength_mg": 400.0, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null }, { "trade_name": "ACNI-CARE 2% LOTION 25 ML (N/A)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 20.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": false, "discontinued": true, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" }, { "id": 1293, "generic": "Acyclovir", "line": 2, "is_adjunct": false, "form": "injection", "strength_mg": 250.0, "adult_dose": "IV: 10 mg/kg/dose every 8 hours.", "adult_duration": "14 to 21 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023", "rationale": "Systemic antiviral therapy for HSV conjunctivitis and ocular infection in newborns.", "cautions": [ "Hypersensitivity to acyclovir, valacyclovir, or any component of the formulation", "Acyclovir IV is an irritant (depending on concentration); avoid extravasation." ], "peds_mgkg_low": 20.0, "peds_mgkg_high": 20.0, "peds_max_mg": null, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "Neonates and children ≤3 months of age: 20 mg/kg every 8 hours given for 14 days for infections of skin, eyes, or mouth or 21 days for disseminated or CNS infections.", "peds_min_weight_kg": null, "peds_max_weight_kg": 6.0, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "SUPRAVIRAN 250MG I.V VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GRUNENTHAL-GERMANY > AL KAMAL IMPORTING & MARKETING CO", "price_egp": 40.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ACICLOVIR VIATRIS 250 MG 5 VIALS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "REIG JOFRE > VIATRIS", "price_egp": 530.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ACIGLOTIR 250 MG LYOPH. PD. FOR IV INF. 5 VIALS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL PHARMACEUTICAL INDUSTRIES", "price_egp": 530.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZOVIRAX 250MG 5 I.V. INF. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 910.0, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" }, { "id": 1295, "generic": "Cefotaxime", "line": 2, "is_adjunct": false, "form": "injection", "strength_mg": null, "adult_dose": "Not applicable - a disease of the first month of life", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (cefotaxime monograph, neonatal dosage)", "rationale": "Ceftriaxone is the card's gonococcal agent and the disease article names cefotaxime 50 mg/kg IM or IV as its substitute when ceftriaxone is not available - a real situation in Egyptian practice. The ENDF's neonatal cefotaxime figure is the same 50 mg/kg at the same routes.", "cautions": [ "Hypersensitivity to cefotaxime, any component of the formulation, or other cephalosporins", "The 50 mg/kg figure is the ENDF's general neonatal dosage for cefotaxime; the ENDF's cefotaxime indication list does not itself name gonococcal conjunctivitis, and the link to this disease comes from the disease article." ], "peds_mgkg_low": 50.0, "peds_mgkg_high": 50.0, "peds_max_mg": null, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "ENDF, general neonatal dosage: 0-1 week, 50 mg/kg IV every 12 hours; 1-4 weeks, 50 mg/kg IV every 8 hours.", "peds_min_weight_kg": null, "peds_max_weight_kg": 5.0, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "CEFAXIM 500MG VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFOTAX (UP PHARMA) 250 MG VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 10.5, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "XORIN 250MG VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 10.5, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFAUSE 500MG VIAL I.M/I.V.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "OTSUKA > BADR PHARMA", "price_egp": 29.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OMNITAXIME 500 MG I.M./I.V.VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > BOSTON MEDICAL", "price_egp": 38.0, "pack_count": null, "unit_price": null, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEFOTAXIME - EVA PHARMA 1 GM I.M./I.V. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 47.5, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLAFORAN 1 GM I.M/I.V. VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 68.0, "pack_count": null, "unit_price": null, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RAMETAX 2 GM I.V./I.M VIAL", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA", "price_egp": 71.0, "pack_count": null, "unit_price": null, "strength_mg": 2000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" }, { "id": 1291, "generic": "Saline eye irrigation", "line": 1, "is_adjunct": true, "form": null, "strength_mg": null, "adult_dose": "Irrigate the eye with sterile isotonic saline, repeated frequently until the discharge stops", "adult_duration": "Until the discharge settles", "dose_source": "No labelled dose - a procedure, not a medicine", "rationale": "Washes away the purulent load while the antibiotic works. It treats nothing on its own.", "cautions": [ "An adjunct. Irrigation without a systemic antibiotic does not treat gonococcal disease and will not stop it perforating a cornea." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Frequent sterile saline irrigation, daily at least, until the eye stops discharging.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "ophthalmia-neonatorum" }, { "id": 1296, "generic": "Azithromycin", "line": 1, "is_adjunct": true, "form": "oral.solid", "strength_mg": 1000.0, "adult_dose": "1 g orally as a single dose - given to the MOTHER and to her sexual partner, not to the baby", "adult_duration": "Single dose", "dose_source": "Ophthalmia neonatorum - disease-level clinical article (ophthalmia-neonatorum-full.txt), Maternal and partner therapy, corroborated by Egyptian National Drug Formulary - Antimicrobial 2023 (azithromycin monograph, Dosage Regimen, Sexually transmitted infections)", "rationale": "The card treated the baby and left the source of the infection untreated. One sentence in the card's own article carries both claims: treating the mother at the same time - azithromycin 1 g by mouth - along with her sexual partners, is essential if reinfection is to be prevented. The Egyptian formulary doses the same regimen for the same purpose, giving 1 g orally as a single dose for a sexually transmitted infection, alone or in combination, under an indication that names the treatment of urethritis and of cervicitis. The information was already on the card as a bare caution; it is now a row with a document behind it, under its own heading so it cannot be mistaken for the baby's dose.", "cautions": [ "THIS DOSE IS FOR THE MOTHER AND HER PARTNER, NOT THE NEWBORN. The article treats it as essential that she and her sexual partners are covered alongside the baby - azithromycin 1 g by mouth for her - because that is what prevents the infection returning.", "Follow-up - the article asks that both the mother and her sexual partner are retested and treated again where needed, which is what keeps the infection from coming back.", "Why it matters - left untreated, maternal gonorrhoea passes to the baby in more than 30% of cases and chlamydia in as many as 50%. That is the whole argument for screening and treating in pregnancy.", "CONTRAINDICATED where there is hypersensitivity to azithromycin itself, to erythromycin, to any other macrolide - the azalides and ketolides included - or to anything else in the product.", "Treat for gonorrhoea as well if that is what the baby has or if it cannot be excluded - this single dose covers chlamydia, and the article's regimen for the newborn's gonococcal disease is a cephalosporin." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "NOT a paediatric row and not the baby's dose. The baby's azithromycin is 20 mg/kg as a single dose, repeated once a week later - see the Chlamydial row on this card.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "AZIROWA 1000 MG 2 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.", "price_egp": 44.0, "pack_count": 2, "unit_price": 22.0, "strength_mg": 1000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHRODOSE 100MG/5ML SUSP. 15ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR > AVERROES PHARMA-EGYPT", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ZITHROPHATE 200MG/5ML SUSP. 15ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORGANO PHARMA > NOVELL PHARMA", "price_egp": 12.75, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "ophthalmia-neonatorum" } ] }