# Norovirus Gastroenteritis

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: CDC Yellow Book 2024 · NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in children under 5 (NCBI Bookshelf NBK63837)
- Verified date: 2026-08

## Verified against

- NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in children under 5 (NCBI Bookshelf NBK63837)
- WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2

## Treatment metadata

- ORS — oral.liquid

## Complete treatment card

```text
NOROVIRUS GASTROENTERITIS
Sources: CDC Yellow Book 2024 · NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in
         children under 5 (NCBI Bookshelf NBK63837)
Review status: REVIEWED against NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in
               children under 5 (NCBI Bookshelf NBK63837), WHO. The treatment of
               diarrhoea: a manual for physicians and other senior health workers,
               4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and
               Table 2  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (6)
    - Sickness, vomiting, cramping belly pain and loose stool, often with muscle aches, headache and
      chills  [abdominal pain · chills · headache · muscle cramps · muscle pain · vomiting]
    - Some people get mainly loose stool, others mainly nausea and vomiting  [nausea · vomiting]
    - Illness usually runs 1 to 3 days, with or without a prodrome
    - Ask about living quarters, water source, recent travel, raw or undercooked food and sick
      contacts
    - A weakened immune system predicts a longer illness and greater risk of serious harm
    - Rarely the picture is neurological, with a fit or a confused, drowsy state  [seizures]
  SIGNS - what you find (4)
    - Belly tenderness is typically mild, diffuse and does not localise  [abdominal tenderness]
    - Marked tenderness or guarding points away from this and needs another cause hunted for
      [guarding]
    - Visibly bloody stool does not fit and calls for further workup
    - Dry mouth, poor skin turgor, fast pulse and a postural blood pressure drop mark dehydration
      [dehydration · dry mouth]
  TESTS (6)
    - Most cases need no test at all
    - A metabolic panel is worth it in selected patients, to check salts and hydration
    - Stool culture, C difficile toxin and ova and parasites only if illness drags on or another
      organism is suspected
    - RT-PCR on stool or vomit is the reference test; enzyme immunoassay is the one more clinics can
      actually get
    - Accuracy swings with how many samples were sent, when the stool was taken and how it was
      handled
    - Outbreak pattern: vomiting in over half of cases, incubation 24 to 48 hours, illness lasting
      12 to 60 hours, and no bacteria grown from stool
  IF NOT THIS - what else fits (4)
    - Other gut infections: rotavirus, cholera, C difficile, Salmonella, Cryptosporidium,
      enterovirus, E coli, Shigella, Campylobacter, Vibrio
    - When belly pain leads, weigh surgical and vascular causes: appendicitis, gallbladder, gut
      obstruction or perforation, diverticulitis, pancreatitis, gut ischaemia, aortic aneurysm
    - Also weigh pregnancy in the tube, twisted ovary or testis, pelvic infection, kidney infection
      and urine infection
    - A heart attack can show up as belly pain and belongs on the list
  Source  StatPearls "Norovirus" - disease-level clinical article
  Status  traced to the source above

1. ORS                                                    [1st line]
   Adult    Make the sachet up to the volume printed on the pack - a WHO/UNICEF standard sachet
            makes 1 litre, and using less water than the label says makes the solution dangerously
            concentrated. Egypt also sells ready-mixed 240-360 mL packs, which need no dilution.
            Drink after each loose stool or vomiting episode.
   Peds     75 mL/kg/dose
            (75 ml/kg over 4 hours for fluid deficit replacement (WHO Plan B),
            plus maintenance fluid. This matches every other rehydration entry
            in the app.)
            3kg -> 225 mL/dose    4kg -> 300 mL/dose    5kg -> 375 mL/dose    6kg -> 450 mL/dose
            7kg -> 525 mL/dose    8kg -> 600 mL/dose    9kg -> 675 mL/dose    10kg -> 750 mL/dose
            11kg -> 825 mL/dose   12kg -> 900 mL/dose   13kg -> 975 mL/dose   14kg -> 1050 mL/dose
            15kg -> 1125 mL/dose  16kg -> 1200 mL/dose  17kg -> 1275 mL/dose  18kg -> 1350 mL/dose
            19kg -> 1425 mL/dose  20kg -> 1500 mL/dose  21kg -> 1575 mL/dose  22kg -> 1650 mL/dose
            23kg -> 1725 mL/dose  24kg -> 1800 mL/dose  25kg -> 1875 mL/dose  26kg -> 1950 mL/dose
            27kg -> 2025 mL/dose  28kg -> 2100 mL/dose  29kg -> 2175 mL/dose  30kg -> 2250 mL/dose
            31kg -> 2325 mL/dose  32kg -> 2400 mL/dose  33kg -> 2475 mL/dose  34kg -> 2550 mL/dose
            35kg -> 2625 mL/dose  36kg -> 2700 mL/dose  37kg -> 2775 mL/dose  38kg -> 2850 mL/dose
            39kg -> 2925 mL/dose  40kg -> 3000 mL/dose  41kg -> 3075 mL/dose  42kg -> 3150 mL/dose
            43kg -> 3225 mL/dose  44kg -> 3300 mL/dose  45kg -> 3375 mL/dose  46kg -> 3450 mL/dose
            47kg -> 3525 mL/dose  48kg -> 3600 mL/dose  49kg -> 3675 mL/dose  50kg -> 3750 mL/dose
   Source   WHO. The treatment of diarrhoea: a manual for physicians and other senior health
            workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2
   Why      Norovirus is self-limiting; management is purely supportive fluid replacement.
   Caution  Never make the solution up in less water than the pack states. A five-fold concentrated
            ORS given to a dehydrated patient causes hypernatraemia, and an infant is the one least
            able to survive it.
            Use strict hand hygiene with soap and water (alcohol sanitizers are less effective
            against norovirus).
            Exclude patient from work/school for 48 hours after symptoms resolve.
            Do not use antidiarrhoeal medications.
   Egypt    GLUCOHYDRAN 10 SACHET.           ARAB DRUG COM...     1.75 EGP
            REHYDRAN N 10 SACHET             CID                  4.50 EGP
            REHYDRO ZINC 10 SACHETS          CID                  7.00 EGP
            ORS 20 SACHETS                   PHAROPHARMA         40.00 EGP
            ELECTRO MASH SYRUP 200 ML        MASH PREMIERE       60.00 EGP
            FLEXOLYTE ORAL REHYDRATION SOL. 240 ML KEMPETRO FOR CHEMICAL INDUSTRIES        65.00 EGP
            HERO ORS 200 ML                  HERO > HERO M...   120.00 EGP
            SANSO ORS SYRUP 140 ML           AUG PHARMA         400.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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