{
  "schema_version": 1,
  "kind": "condition",
  "id": "norovirus",
  "name": "Norovirus Gastroenteritis",
  "category": "infectious",
  "sources": "CDC Yellow Book 2024 · NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in children under 5 (NCBI Bookshelf NBK63837)",
  "review_status": "reviewed",
  "verified_against": "NICE CG84 Diarrhoea and vomiting caused by gastroenteritis in children under 5 (NCBI Bookshelf NBK63837) · WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1266,
      "generic": "ORS",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.liquid",
      "strength_mg": null,
      "adult_dose": "Make the sachet up to the volume printed on the pack - a WHO/UNICEF standard sachet makes 1 litre, and using less water than the label says makes the solution dangerously concentrated. Egypt also sells ready-mixed 240-360 mL packs, which need no dilution. Drink after each loose stool or vomiting episode.",
      "adult_duration": null,
      "dose_source": "WHO. The treatment of diarrhoea: a manual for physicians and other senior health workers, 4th rev. Geneva: WHO; 2005 (IRIS 10665/43209), section 4.3.1 and Table 2",
      "rationale": "Norovirus is self-limiting; management is purely supportive fluid replacement.",
      "cautions": [
        "Never make the solution up in less water than the pack states. A five-fold concentrated ORS given to a dehydrated patient causes hypernatraemia, and an infant is the one least able to survive it.",
        "Use strict hand hygiene with soap and water (alcohol sanitizers are less effective against norovirus).",
        "Exclude patient from work/school for 48 hours after symptoms resolve.",
        "Do not use antidiarrhoeal medications."
      ],
      "peds_mgkg_low": 75.0,
      "peds_mgkg_high": 75.0,
      "peds_max_mg": null,
      "peds_basis": "dose",
      "peds_unit": "mL",
      "peds_note": "75 ml/kg over 4 hours for fluid deficit replacement (WHO Plan B), plus maintenance fluid. This matches every other rehydration entry in the app.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 750,
          "high_mg": 750,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 1500,
          "high_mg": 1500,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 2250,
          "high_mg": 2250,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 3000,
          "high_mg": 3000,
          "capped": false
        }
      ],
      "brands": [
        {
          "trade_name": "GLUCOHYDRAN 10 SACHET.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 1.75,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "REHYDRAN N 10 SACHET",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 4.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "REHYDRO ZINC 10 SACHETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CID",
          "price_egp": 7.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ORS 20 SACHETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 40.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ELECTRO MASH SYRUP 200 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MASH PREMIERE",
          "price_egp": 60.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLEXOLYTE ORAL REHYDRATION SOL. 240 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KEMPETRO FOR CHEMICAL INDUSTRIES",
          "price_egp": 65.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "HERO ORS 200 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "HERO > HERO MEA TRADING",
          "price_egp": 120.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SANSO ORS SYRUP 140 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "AUG PHARMA",
          "price_egp": 400.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "norovirus"
    }
  ]
}