# Nausea

- Category: acute
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - git.pdf, Domperidone monograph (chapter PDF p36) · Egyptian National Drug Formulary - git.pdf, Metoclopramide monograph (chapter PDF p39)
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - git.pdf, Domperidone monograph (chapter PDF p36)
- Egyptian National Drug Formulary - git.pdf, Metoclopramide monograph (chapter PDF p39)

## Treatment metadata

- Metoclopramide — injection
- Domperidone — oral.solid

## Complete treatment card

```text
NAUSEA
Sources: Egyptian National Drug Formulary - git.pdf, Domperidone monograph (chapter PDF p36) ·
         Egyptian National Drug Formulary - git.pdf, Metoclopramide monograph (chapter PDF p39)
Review status: REVIEWED against the source listed above  (2026-08)

1. METOCLOPRAMIDE                                         [1st line]
   Adult    10 mg orally, IV, or IM, repeated up to three times daily (maximum 30 mg or 0.5 mg/kg
            per day) - Maximum 5 days
   Peds     1 to 18 years: Second line only: 0.1 to 0.15 mg/kg by mouth, IM or IV, up to three times
            daily, maximum 0.5 mg/kg in 24 hours. Not established under 1 year.
            (Ages 1-18 years, as a second-line agent: 0.1 to 0.15 mg/kg oral/IM/IV up to three times
            daily, maximum 0.5 mg/kg in 24 hours; safety and efficacy not established under 1 year.)
   Source   Egyptian National Drug Formulary - git.pdf, Metoclopramide monograph (chapter PDF p39)
   Why      First-line, widely available antiemetic covering the formulary's general 'symptomatic
            treatment of nausea and vomiting' indication, which fits this non-specific presentation
            directly.
   Caution  Extrapyramidal reactions can occur (acute dystonia, especially in young women) - limit
            to 5 days for this reason.
            Avoid in Parkinson's disease and in known/suspected bowel obstruction or perforation.
            Cardiac symptoms accompanying nausea need urgent cardiac workup, not just an antiemetic.
            Severe dehydration or inability to keep fluids down needs IV rehydration, not oral
            therapy alone.
            RED FLAG - Chest pain accompanying nausea, signs of raised intracranial pressure (severe
            headache, neurological deficit), signs of bowel obstruction or peritonitis, or severe
            dehydration or inability to keep fluids down, especially in pregnancy.
   Egypt    AMETIC 10MG/2ML 3 AMP. FOR I.M./I.V. INJ. EIMC > PHAROPHARMA                    3.75 EGP
            PLEMAZOL 10MG/2ML 5 AMP.         CID                  3.80 EGP
            METOCLOPRAMIDE 10MG/2ML 5 AMP. FOR IV/IM INJ. SEDICO                            8.00 EGP
            MECLOPRAM 10MG/2ML 5 I.M./I.V.AMP. ALEXANDRIA                                  40.00 EGP
            PRIMPERAN 10MG/2ML 12 AMP.       SANOFI              60.00 EGP
            SUNNYPYRAMID 10MG/2ML 50 AMP.    SUNNY MEDICAL      400.00 EGP

2. DOMPERIDONE                                            [2nd line]
   Adult    10 mg orally up to three times daily (maximum 30 mg per day) - Lowest effective dose for
            the shortest duration, maximum 1 week
   Peds     Not recommended in children under 12 years or in adolescents weighing less than 35 kg
            per this formulary.
   Source   Egyptian National Drug Formulary - git.pdf, Domperidone monograph (chapter PDF p36)
   Why      Formulary indication is simply 'relief of the symptoms of nausea and vomiting', a direct
            match for this non-specific complaint, and it is a useful alternative to metoclopramide.
   Caution  Taken by mouth, not rectally: the dose text reads '10 mg orally up to three times
            daily'.
            There is a QT-interval prolongation risk - avoid with other QT-prolonging drugs and in
            significant cardiac or electrolyte disease.
            Does not cross the blood-brain barrier well, so lower extrapyramidal risk than
            metoclopramide - a reasonable alternative when EPS is a concern.
            The maximum duration is one week per formulary; re-assess if symptoms persist.
   Egypt    DOMPIDONE 10 MG 30 TAB.          ARAB DRUG COM...    17.25 EGP (0.57/unit)
            SYNCHROGIT 10MG 20 TAB.          RAMEDA              15.00 EGP (0.75/unit)
            MOTINORM 10MG 30 TABS.           GLAXO SMITHKLINE    28.25 EGP (0.94/unit)
            GASTROMOTIL 10MG 20 F.C. TAB.    EIPICO              26.00 EGP (1.30/unit)
            MOTILIUM 10MG 40 F.C.TAB.        MINA PHARM > ...   100.00 EGP (2.50/unit)
            GASTRONORM 10MG 5 SACHET         SIGMA                5.50 EGP
            MOTIL FAST 10 MG 10 EFF. SACHETS AMOUN               26.00 EGP
            DONARAX 10 MG 30 ORODISPERSIBLE TABS. JEDCO INT. CO. FOR PHARMACEUTICALS...    39.00 EGP
            DOMPIDONE 100MG/100ML ORAL SUSP. 100ML ARAB DRUG COMPANY (ADCO)                 6.00 EGP
                -> ? strength differs, ? different route - not oral solid
            MOTILIUM 1MG/ML SUSP. 100ML      MINA PHARM > ...    15.75 EGP
                -> ? strength differs, ? different route - not oral solid

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement.

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