{ "schema_version": 1, "kind": "condition", "id": "nasal-polyp", "name": "Nasal Polyp", "category": "acute", "sources": "Egyptian National Drug Formulary - endocrine.pdf, Prednisolone monograph (chapter PDF p183) · Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77) · del Toro E, Hardin FML, Portela J. Nasal Polyps. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Last Update: May 5, 2025.", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - endocrine.pdf, Prednisolone monograph (chapter PDF p183) · Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77) · del Toro E, Hardin FML, Portela J. Nasal Polyps. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Last Update: May 5, 2025.", "verified_date": "2026-08", "treatments": [ { "id": 1246, "generic": "Fluticasone", "line": 1, "is_adjunct": false, "form": "spray", "strength_mg": null, "adult_dose": "Half of the 400 mcg mono-dose nasal drop container instilled into each nostril once or twice daily.", "adult_duration": "As directed; reassess and consider ENT referral if polyps or obstruction persist.", "dose_source": "Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77)", "rationale": "The formulary specifically indicates fluticasone mono-dose nasal drops for management of nasal polyps and related obstruction, making it the direct first-choice treatment.", "cautions": [ "Given as a nasal drop, not swallowed: the dose is a 400 mcg mono-dose drop instilled into each nostril.", "A unilateral polyp, especially with bleeding, needs ENT referral to exclude a tumour rather than being treated as routine polyposis.", "Polyps in a child are rare and warrant work-up for cystic fibrosis.", "Local irritation, dryness, or epistaxis can occur.", "Refer to ENT if polyps are large or symptoms persist despite treatment." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Labelled for adults, the elderly, and children over 16 years for this nasal-drop formulation; nasal polyps in a younger child are rare and warrant ENT referral rather than routine treatment (consider cystic fibrosis).", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "RHINORELIEF NASAL SUSP. 50 MCG/METERED SPRAY DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TICANASE 0.05% NASAL SPRAY 12 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 70.0, "pack_count": null, "unit_price": null, "strength_mg": 12000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIX NASAL SPRAY 50 MCG/METERED SPRAY DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 76.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLOHALE HFA 250MCG/DOSE AEROSOL 120 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CIPLA LTD. - INDIA > STAR INTERNATIONAL COMPANY", "price_egp": 95.0, "pack_count": null, "unit_price": null, "strength_mg": 0.25, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXONASE 50 MCG/METERED NASAL SPRAY 120 DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 133.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "nasal-polyp" }, { "id": 1247, "generic": "Prednisolone", "line": 3, "is_adjunct": true, "form": "oral.solid", "strength_mg": null, "adult_dose": "Oral, added short-term to intranasal steroid for larger or more symptomatic polyps: initial 5-60 mg/day as a single daily dose or in 2-4 divided doses, using the lowest dose that controls symptoms.", "adult_duration": "Short course only; ENT/specialist input on exact duration and tapering is advised, since the formulary gives only its general oral corticosteroid dosing framework, not a polyp-specific regimen. Do not withdraw abruptly, particularly after doses of 40 mg or more or courses of 3 weeks or more.", "dose_source": "Egyptian National Drug Formulary - endocrine.pdf, Prednisolone monograph (chapter PDF p183)", "rationale": "A short course of oral corticosteroid is commonly added to intranasal steroid treatment to shrink larger or more symptomatic nasal polyps; the formulary provides only its general systemic corticosteroid dosing framework rather than a polyp-specific regimen, so this is used adjunctively and short-term, ideally with ENT guidance on course length.", "cautions": [ "The formulary gives only the general oral corticosteroid dosing framework for prednisolone - it does not specify a nasal-polyp-specific dose or course length, so use the shortest effective course and taper per general corticosteroid principles, ideally with ENT input.", "Do not withdraw abruptly, particularly after doses of 40 mg or more or courses of 3 weeks or more.", "Systemic steroid side effects (hyperglycaemia, mood change, GI irritation, infection risk) increase with dose and duration - avoid repeated or prolonged courses.", "A unilateral polyp, especially with bleeding, needs ENT referral to exclude a tumour before treating as routine polyposis." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "The formulary's general paediatric anti-inflammatory dosing (0.1-2 mg/kg/day) is specialist-set and is not reproduced here; nasal polyps in a child need ENT referral rather than routine oral steroid treatment.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "HOSTACORTIN H 5MG 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 12.0, "pack_count": 30, "unit_price": 0.4, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE 5 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 24.0, "pack_count": 20, "unit_price": 1.2, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDILONE 5MG 10 TAB. (25 STRIPS PACK)", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 250.0, "pack_count": 10, "unit_price": 25.0, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE-EVA 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 79.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SOLUPRED ORO 5 MG 30 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI WINTHROP > SANOFI", "price_egp": 84.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNISOLONE 20 MG 20 ORODISPERSIBLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 115.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "XILONE 20 MG 20 ORODISPERSABLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 142.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DISPRELONE-OD 20 MG 30 ORODISPERSABLE TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ANDALOUS PHARMA", "price_egp": 202.5, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ACETASEE 1% EYE DROPS (SUSP.) 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "PREDNIS 5MG/5ML SYRUP 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 9.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "nasal-polyp" } ] }