{
  "schema_version": 1,
  "kind": "condition",
  "id": "molluscum-contagiosum",
  "name": "Molluscum Contagiosum",
  "category": "infectious",
  "sources": "Molluscum Contagiosum - StatPearls - NCBI Bookshelf (NBK441898), Treatment / Management, which lists the agent among topical therapies - \"cantharidin (now available as VP-102), potassium hydroxide, podophyllotoxin, and the newly Food and Drug Administration (FDA)-approved berdazimer gel (Zelsuvmi)\" - and states neither a strength nor an application schedule. The 5% cutaneous solution twice daily to a maximum of 14 days is the MolluDab product instruction; MolluDab is a CE-marked device rather than a licensed medicine and has no SmPC in this corpus. · BAD Guidelines for Molluscum Contagiosum 2017 · Salactol Collodion (salicylic acid 16.7% + lactic acid 16.7%) SmPC sections 4.2-4.3 (eMC product 3766)",
  "review_status": "reviewed",
  "verified_against": "Molluscum Contagiosum - StatPearls - NCBI Bookshelf (NBK441898), Treatment / Management, which lists the agent among topical therapies - \"cantharidin (now available as VP-102), potassium hydroxide, podophyllotoxin, and the newly Food and Drug Administration (FDA)-approved berdazimer gel (Zelsuvmi)\" - and states neither a strength nor an application schedule. The 5% cutaneous solution twice daily to a maximum of 14 days is the MolluDab product instruction; MolluDab is a CE-marked device rather than a licensed medicine and has no SmPC in this corpus. · Salactol Collodion (salicylic acid 16.7% + lactic acid 16.7%) SmPC sections 4.2-4.3 (eMC product 3766)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1215,
      "generic": "Salicylic acid",
      "line": 1,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 10-12% solution carefully to lesion center once daily at night",
      "adult_duration": "2-4 weeks",
      "dose_source": "Salactol Collodion (salicylic acid 16.7% + lactic acid 16.7%) SmPC sections 4.2-4.3 (eMC product 3766)",
      "rationale": "Keratolytic that softens and dissolves the central keratin plug of molluscum lesions to hasten clearance; used when watchful waiting, the preferred first approach, is not acceptable to the patient or lesions persist.",
      "cautions": [
        "Watchful waiting is preferred initial approach as lesions resolve spontaneously within 6-18 months.",
        "Protect surrounding normal skin with soft paraffin before applying keratolytic.",
        "Avoid squeezing or scratching lesions to prevent autoinoculation and scarring.",
        "Not on or near the face, in skin folds, or on the anogenital area - which is where much molluscum actually sits. If the lesions are there, this is the wrong treatment, not a treatment to apply carefully.",
        "Not for a diabetic foot, and not where circulation to the foot is poor. The label rules both out flatly. A keratolytic on skin that heals badly is how a wart becomes an ulcer."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Apply carefully onto lesion only, avoiding surrounding normal skin",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "SALICYLIC ACID COLLODION 12% PAINT B.P.2001",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UNIPHARMA CO. > UNIPHARMA",
          "price_egp": 3.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SALICYLIC ACID SOAP (WEISER) 45 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "WEISER",
          "price_egp": 15.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 45000.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "molluscum-contagiosum"
    },
    {
      "id": 1216,
      "generic": "Potassium hydroxide",
      "line": 2,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 5% cutaneous solution twice daily precisely to umbilicated papules until inflammation occurs (max 14 days)",
      "adult_duration": "until inflammation occurs (max 14 days)",
      "dose_source": "Molluscum Contagiosum - StatPearls - NCBI Bookshelf (NBK441898), Treatment / Management, which lists the agent among topical therapies - \"cantharidin (now available as VP-102), potassium hydroxide, podophyllotoxin, and the newly Food and Drug Administration (FDA)-approved berdazimer gel (Zelsuvmi)\" - and states neither a strength nor an application schedule. The 5% cutaneous solution twice daily to a maximum of 14 days is the MolluDab product instruction; MolluDab is a CE-marked device rather than a licensed medicine and has no SmPC in this corpus.",
      "rationale": "Topical alkaline solution induces local inflammatory response leading to clearance.",
      "cautions": [
        "CONTRAINDICATED in children under 2 years; do NOT apply to facial, periorbital, mucosal, or genital lesions (risk of severe chemical burn and permanent scarring).",
        "Causes localized erythema and stinging which signals immune reaction and resolution; stop application once local inflammation appears.",
        "Apply strictly to the central umbilication, protecting surrounding healthy skin."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Apply twice daily to lesions under adult supervision; stop application once lesion becomes inflamed",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "molluscum-contagiosum"
    }
  ]
}