# Acute non-specific low back pain

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian Drug Authority (EDA) Prescribing Information · Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 7020)
- Verified date: 2026-08

## Verified against

- Egyptian Drug Authority (EDA) Prescribing Information
- Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 7020)
- Acute non-specific low back pain - disease-level clinical article (low-back-pain-clinical.txt)

## Treatment metadata

- Ibuprofen — 400 mg — oral.solid
- Referral & safety-netting (no drug therapy)
- Methocarbamol + Paracetamol — oral.solid

## Complete treatment card

```text
ACUTE NON-SPECIFIC LOW BACK PAIN
Sources: Egyptian Drug Authority (EDA) Prescribing Information · Ibuprofen 400 mg film-coated
         tablets SmPC section 4.2 Posology and method of administration (eMC product 7020)
Review status: REVIEWED against Egyptian Drug Authority (EDA) Prescribing Information, Ibuprofen 400
               mg film-coated tablets SmPC section 4.2 Posology and method of
               administration (eMC product 7020), Acute non-specific low back pain
               - disease-level clinical article (low-back-pain-clinical.txt)
               (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (5)
    - Pain present under 6 weeks is usually mechanical strain, while pain over 12 weeks reflects a
      longstanding mechanical or other condition  [back pain]
    - New difficulty starting urination, bowel changes, or numbness around the saddle area are key
      cauda equina warning symptoms  [numbness]
    - Sciatica affecting both legs, rapidly worsening leg pain, or new weakness in both legs raises
      serious concern for nerve root compression  [back pain · sciatica]
    - In children, night-time pain and age under 4 raise concern for tumour or infection  [back
      pain]
    - Morning stiffness lasting more than 30 minutes that eases with movement or heat points toward
      an inflammatory cause  [joint stiffness]
  SIGNS - what you find (8)
    - The straight-leg-raise test is positive for disc herniation if raising the leg to under 60
      degrees reproduces pain on that side  [back pain · disc herniation]
    - The crossed straight-leg-raise (raising the other leg) is more specific than the standard test
      for disc herniation  [disc herniation]
    - The Stork test for spondylolysis is positive if standing on one leg and arching backward
      reproduces the pain  [back pain]
    - The Adam forward-bend test can reveal a rib or back hump pointing to scoliosis
    - Bruising, scrapes, or tenderness over the spinous processes can suggest a fracture  [bruising]
    - Progressive limb weakness or numbness, new loss of bladder or bowel control, saddle numbness,
      or a slack anal sphincter suggest cauda equina compression  [numbness]
    - Leg weakness or numbness that eases with rest (neurogenic claudication) suggests spinal
      stenosis  [claudication · leg weakness · numbness · stricture]
    - A vertebral compression fracture causes pain that worsens on bending forward with a tender
      point on palpation  [back pain]
  TESTS (10)
    - Fewer than 5-10% of low back pain cases have a specific spinal cause; 90-95% are nonspecific
      mechanical pain that does not need routine imaging
    - Disc degeneration shows up on imaging in more than 80% of adults over 50 even without symptoms
    - In adults, imaging is reserved for pain lasting over 6 weeks despite conservative treatment;
      in children, pain lasting over 4 weeks
    - MRI is favoured when nerves, discs, or other soft tissue are suspected to be involved
    - CT or MR angiography is used when aortic dissection is suspected
    - Rheumatology panels (HLA-B27, ANA, rheumatoid factor, Lyme antibodies) are usually nonspecific
      and not routinely useful
    - CRP and ESR are useful inflammatory markers when infection or an inflammatory disease is
      suspected
    - Raised LDH and uric acid can point to a rapid marrow turnover process such as leukaemia
    - Around 97% of spinal tumours found are metastatic rather than a primary cancer
    - Vertebral fractures account for roughly 0.4-5.6% of low back pain presentations
  IF NOT THIS - what else fits (12)
    - A muscle or ligament strain causes pain that worsens with movement and eases with rest, with
      restricted movement and tenderness on palpation
    - Lumbar spondylosis affects those over 40 and may bring hip pain
    - Disc herniation, usually at L4-S1, causes numbness, sensory change, and weakness along the
      affected nerve root
    - Spondylolysis or spondylolisthesis pain can radiate into the buttock and back of the thigh
    - A spinal tumour is suggested by unexplained weight loss and focal tenderness along with
      malignancy risk factors
    - A spinal infection is suggested by recent spinal surgery, IV drug use, or immune suppression
      together with fever, localized pain, or a wound
    - Aortic dissection can cause tearing back pain, more common in older adults with vascular
      disease
    - In younger patients, aortic dissection is often linked to a connective tissue disorder such as
      Marfan, Ehlers-Danlos, or Loeys-Dietz syndrome
    - In children, a bone tumour causing back pain, especially osteoid osteoma, classically eases
      with NSAIDs
    - Childhood epidural abscess should be suspected if there are neurological deficits or nerve-
      root pain
    - Scheuermann kyphosis presents with chronic back pain and a rigid, fixed curve
    - A psychological cause (conversion or somatisation) is suggested by persistent pain despite a
      normal physical exam
  Source  StatPearls "Low Back Pain: Evaluation and Management" - disease-level clinical article
  Status  traced to the source above

1. IBUPROFEN                                              [1st line]
   Adult    400 mg orally 3 times daily with food - shortest duration needed (up to 1-2 weeks)
   Peds     Low back pain in children <16 years requires urgent pediatric evaluation to exclude
            serious organic etiology (discitis, infection, tumor); routine primary care NSAID
            management is not recommended.
   Source   Ibuprofen 400 mg film-coated tablets SmPC section 4.2 Posology and method of
            administration (eMC product 7020)
   Why      NSAID that reduces pain and inflammation through COX inhibition; first-line analgesic
            for acute non-specific low back pain, used to keep the patient mobile rather than
            confined to bed rest.
   Caution  Screen for RED FLAGS (cauda equina, fever, weight loss, progressive deficit).
            Encourage remaining active; avoid prolonged bed rest.
            Co-prescribe PPI in elderly or high GI risk patients.
   Egypt    DAJUANOFEN 400 MG 20 F.C. TABS.  COPAD PHARMA         5.00 EGP (0.25/unit)
            FLABU 400MG 10 F.C.TAB.          DELTA PHARMA         3.75 EGP (0.38/unit)
            NOVA-PROFEN 400MG 30 F.C. TABLETS SANOFI                           12.75 EGP (0.42/unit)
            IBUPROFEN 400 MG 10 TAB.         SEDICO               6.00 EGP (0.60/unit)
            MAFO 400 MG  30 F.C.TABS         EIPICO              42.00 EGP (1.40/unit)
            BRUFEN 400 MG 30 TABS.           KAHIRA > ABBO...    78.00 EGP (2.60/unit)
            PROFUSOL 400MG 20 S.G CAPS.      EUROPEAN EGYP...    31.00 EGP
            ANALGIPROF 400 MG 25 SACHETS     EVA PHARMA          37.50 EGP
            NOVA-PROFEN  100MG/5ML ORAL SUSP. 100ML SANOFI                                  2.25 EGP
                -> ? strength differs, ? different route - not oral solid
            BRUFEMOL-N SUSP. 60 ML           ARAB DRUG COM...     4.50 EGP
                -> ? strength differs, ? different route - not oral solid

2. REFERRAL & SAFETY-NETTING (NO DRUG THERAPY)            [1st line]
   Adult    
   Source   Acute non-specific low back pain - disease-level clinical article (low-back-pain-
            clinical.txt)
   Why      Carries the referral criteria and warning signs for this condition, which apply
            whichever treatment is chosen.
   Caution  RED FLAG - Nighttime pain, fever, bowel or bladder dysfunction, or progressive
            neurologic deficits require urgent evaluation and referral.

3. METHOCARBAMOL + PARACETAMOL                            [add-on - not a substitute]
   Adult    1-2 tablets (400 mg methocarbamol / 325 mg paracetamol) 3-4 times daily x up to 5 days
            max
   Peds     Not recommended in pediatric care
   Source   Egyptian Drug Authority (EDA) Prescribing Information
   Why      Included per Egyptian Drug Authority (EDA) prescribing practice as a short-term adjunct
            for acute severe muscle spasm. NICE NG59 does not name muscle relaxants at all - this is
            EDA practice alone, not a NICE-supported exception.
   Caution  This is a short-term adjunct for severe painful muscle spasm in acute strain.
            May cause drowsiness and dizziness; caution when driving.
            Avoid alcohol and sedatives during therapy.
   Egypt    AWADIST RELAX 20 F.C. TABS.      HIGH PERFORMA...    30.00 EGP (1.50/unit)
            FLEXPRO EXTRA  20 F.C.TABS.      MUP                 46.00 EGP (2.30/unit)
            METHOBAMOL 20 F.C. TABS.         ARAB CAPS > O...    46.00 EGP (2.30/unit)
            METHORELAX 30 TAB.               SIGMA > GENNE...    81.00 EGP (2.70/unit)

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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