# Lactation problems

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - Endocrine System 2024 (cabergoline monograph) · No dose - assessment step, no medicine given · National Guideline Alliance (UK) / National Institute for Health and Care Excellence (NICE). Postnatal care. NICE guideline NG194. London: NICE. Published 20 April 2021; last updated 9 June 2026. Recommendations 1.5.15 and 1.5.21.
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - Endocrine System 2024 (cabergoline monograph)
- No dose - assessment step, no medicine given

## Treatment metadata

- No drug therapy in primary care (Assess first)
- Cabergoline — 0.5 mg — oral.solid

## Complete treatment card

```text
LACTATION PROBLEMS
Sources: Egyptian National Drug Formulary - Endocrine System 2024 (cabergoline monograph) · No dose
         - assessment step, no medicine given · National Guideline Alliance (UK) / National
         Institute for Health and Care Excellence (NICE). Postnatal care. NICE guideline NG194.
         London: NICE. Published 20 April 2021; last updated 9 June 2026. Recommendations 1.5.15 and
         1.5.21.
Review status: REVIEWED against 2 sources listed above  (2026-08)

Rx: Main treatment  |  Suppressing lactation - not for low supply

MAIN TREATMENT
1. NO DRUG THERAPY IN PRIMARY CARE (ASSESS FIRST)         [1st line]
   Adult    Nearly every lactation problem is solved by watching a feed, not by prescribing. Poor
            attachment, infrequent or timed feeding, nipple pain, engorgement and tongue-tie account
            for most of what is reported as 'not enough milk'. Skilled breastfeeding support and
            more frequent, effective feeding raise supply. No medicine raises supply reliably. The
            cabergoline entry below is for the opposite problem - suppressing lactation when a
            mother is not going to breastfeed - and not for low supply. - Assess, then decide
   Peds     Adult-only condition - paediatric section not applicable
   Source   No dose - assessment step, no medicine given
   Why      Domperidone is widely used off-label as a galactagogue and is deliberately not offered
            here: it is unlicensed for this purpose, the European and UK regulators restricted it
            over QT prolongation and sudden cardiac death, and the evidence for a clinically
            meaningful increase in supply is weak. Feeding support is what works.
   Caution  A red, painful, wedge-shaped area with fever is mastitis. Keep feeding or expressing
            from that breast, and add an antibiotic if it has not settled within 12-24 hours or the
            mother is unwell.
            A fluctuant lump that does not settle is a breast abscess - refer for drainage.
            Domperidone as a galactagogue is off-label and carries a cardiac warning. It is not
            recommended here.
            Failure of lactation after a delivery complicated by major haemorrhage, especially with
            fatigue and cold intolerance, raises Sheehan's syndrome. Check thyroid and pituitary
            function.
            Milk production that continues long after weaning, or in a woman who has not been
            pregnant, is galactorrhoea - check prolactin and thyroid function, and review her drug
            list.
            Watch the baby, not the breast. Wet nappies, weight gain along the centile and audible
            swallowing are what tell you the supply is adequate; the feel of the breast does not.


SUPPRESSING LACTATION - NOT FOR LOW SUPPLY
2. CABERGOLINE                                            [2nd line]
   Adult    1 mg as a single dose, or the better-tolerated 0.25 mg (half a 0.5 mg tablet) every 12
            hours for two days, which comes to the same 1 mg total. Give within the first 24 hours
            after delivery. - Single course
   Peds     Adult-only condition - paediatric section not applicable
   Source   Egyptian National Drug Formulary - Endocrine System 2024 (cabergoline monograph)
   Why      The other direction of the same problem. When lactation has to be stopped for a medical
            reason - a stillbirth, a neonatal death, or a contraindication to breastfeeding - this
            is the drug the Egyptian formulary names for inhibiting it, and it works best given in
            the first day.
   Caution  This suppresses lactation and the effect is not easily reversed. Never give it to a
            woman who may want to breastfeed - confirm the intention before prescribing.
            Contraindicated in pre-eclampsia, eclampsia, and postpartum or uncontrolled
            hypertension. Check the blood pressure before giving it.
            Contraindicated where there is a history of psychosis or a risk of puerperal psychosis.
            Contraindicated in fibrotic disorders of the heart valves, lungs or retroperitoneum, and
            in severe liver impairment.
            Postural hypotension and dizziness are common in the first days. Warn her before she
            stands up holding the baby.
            Given later than the first 24 hours it works less well, and established engorgement
            still needs support measures - a firm bra, cold packs, and analgesia.
   Egypt    CABERGOLACTO 0.5 MG 2 TABS.      IDI > NOVELL ...    36.00 EGP (18.00/unit)
            CABERGLOBE 0.5 MG 2 TABS.        EGPI > GLOBE ...    45.00 EGP (22.50/unit)
            MARVIGOLINE 0.5 MG 2 TABS.       RAMEDA              66.00 EGP (33.00/unit)
            CABROSTINEX 0.5 MG 8 TABS.       MEDIZEN PHARM...   339.00 EGP (42.38/unit)
            GOLINOTECH 0.5 MG 2 TABS.        EUROPEAN EGYP...   103.00 EGP (51.50/unit)
            DOSTILACT 0.5 MG 2 TABS.         ATCO PHARMA >...   105.00 EGP (52.50/unit)
            DOSTINEX 0.5 MG 2 TABS.          PFIZER             172.00 EGP (86.00/unit)
            DELCABRIN 0.5 MG 2 SCORED TABS.  EGPI > HEALTH...   105.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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Dawaa Reference is a reference for prescribers, not a medical device, and does not replace clinical judgement.

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