{ "schema_version": 1, "kind": "condition", "id": "irritable-airways", "name": "Irritable Airways", "category": "acute", "sources": "Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77) · Egyptian National Drug Formulary - respiratory-2026.pdf, Salbutamol monograph (chapter PDF p48) · Goldin J, Cataletto ME. Asthma. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Updated 2024 May 3. Bookshelf ID: NBK430901; PMID: 28613651.", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77) · Egyptian National Drug Formulary - respiratory-2026.pdf, Salbutamol monograph (chapter PDF p48)", "verified_date": "2026-08", "treatments": [ { "id": 1067, "generic": "Salbutamol", "line": 1, "is_adjunct": false, "form": "oral.inhalation", "strength_mg": null, "adult_dose": "Oral inhalation, one inhalation (100 mcg) or two inhalations up to 4 times a day for persistent symptoms. The maximum daily dose should not exceed 8 inhalations and should usually not be repeated more often than every 4 hours.", "adult_duration": "As directed, for symptomatic episodes", "dose_source": "Egyptian National Drug Formulary - respiratory-2026.pdf, Salbutamol monograph (chapter PDF p48)", "rationale": "Salbutamol is the formulary-indicated bronchodilator for bronchospasm of any cause and is the appropriate first-line, as-needed treatment for airway hyperreactivity presenting with cough, wheeze, or chest tightness.", "cautions": [ "Inhaled, not swallowed: the dose is the metered-dose inhaler's 100 mcg per actuation.", "Severe breathlessness, inability to speak in full sentences, or a silent chest is a medical emergency - needs immediate high-dose salbutamol, oxygen, and urgent transfer, not routine dosing.", "Tremor, tachycardia, and palpitations are common; caution in cardiac disease and arrhythmia.", "Frequent as-needed use (more than a few times a week) suggests the need for regular preventer therapy rather than reliever alone." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children under 12 years: one inhalation (100 mcg) or two inhalations up to 4 times daily, maximum daily dose 800 mcg and no more than 6 times in 24 hours; over 12 years, dose as per adults.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Under 12 years", "age_min_months": 0, "age_max_months": 143, "dose_text": "One inhalation (100 mcg), or two inhalations, up to 4 times daily. Maximum 800 mcg a day and no more than 6 times in 24 hours." }, { "label": "12 years and over", "age_min_months": 144, "age_max_months": 216, "dose_text": "As for adults." } ], "peds_doses": null, "brands": [ { "trade_name": "AEROLIN 100MCG/DOSE INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO > 3M HEALTH CARE-U.K.", "price_egp": 7.3, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BUTALIN 100MCG/ACTUATION 200 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JULPHAR", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SALBOVENT RESPIRATOR 5MG/ML SOLN. 20 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 17.5, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BRONCHOLIN S 0.5% RESPIRATOR SOLN. 30 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 37.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALVEOTRACK 5 MG/ML INH. SOLN. 30 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MDI PHARMA", "price_egp": 49.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VENTAL INHALER 100 MCG/DOSE 200 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 72.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VENTOLIN DISKUS 200MCG/DOSE ACCUHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 86.0, "pack_count": null, "unit_price": null, "strength_mg": 0.2, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VENTOLIN EVOHALER 100MCG/ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 86.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPICHESTAL SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 2.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "SALBUTAMOL 2MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 3.5, "pack_count": null, "unit_price": null, "strength_mg": 2.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "irritable-airways" }, { "id": 1068, "generic": "Fluticasone", "line": 2, "is_adjunct": true, "form": "oral.inhalation", "strength_mg": null, "adult_dose": "Mild asthma: starting dose is 100 micrograms twice daily.", "adult_duration": "As directed, reviewed periodically and titrated down once controlled", "dose_source": "Egyptian National Drug Formulary - respiratory-2026.pdf, Fluticasone monograph (chapter PDF p77)", "rationale": "Fluticasone oral inhalation is formulary-indicated for asthma maintenance and prophylaxis; it is added as a regular preventer when airway hyperreactivity is frequent enough to need more than an as-needed reliever.", "cautions": [ "Inhaled, not swallowed: the monograph gives this strictly as an oral inhalation dose.", "Regular inhaled steroid is for frequent/recurrent symptoms and is added to, not a substitute for, the as-needed salbutamol reliever.", "Rinse the mouth after each dose to reduce the risk of oral candidiasis; hoarseness can occur.", "Severe breathlessness or a silent chest is an emergency needing salbutamol and urgent transfer, not the preventer dose.", "Frequent or worsening symptoms despite this dose should prompt formal asthma assessment rather than further self-titration." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Oral inhalation is only specified for children over 16 years in this monograph: starting dose 50-100 micrograms twice daily, maximum 200 mcg twice daily if not sufficiently controlled; dosing for younger children with reactive airways is specialist-set and is not reproduced here.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Over 16 years", "age_min_months": 192, "age_max_months": 216, "dose_text": "Inhaled: 50 to 100 micrograms twice daily to start, to a maximum of 200 mcg twice daily if not sufficiently controlled. Below this age the dose is specialist-set." } ], "peds_doses": null, "brands": [ { "trade_name": "FLIXOTIDE DISKUS 50MCG/DOSE ACCUHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 36.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE 0.5MG/2ML 10 INH. NEBULES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 63.0, "pack_count": null, "unit_price": null, "strength_mg": 0.5, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE EVOHALER 250MCG/ACTUATION 60 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 78.0, "pack_count": null, "unit_price": null, "strength_mg": 0.25, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE DISKUS 100MCG/DOSE 60 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 107.0, "pack_count": null, "unit_price": null, "strength_mg": 0.1, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE EVOHALER 50MCG/ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 111.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE EVOHALER 125MCG/ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 141.0, "pack_count": null, "unit_price": null, "strength_mg": 0.125, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE DISKUS 250 MCG/DOSE 60 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 150.0, "pack_count": null, "unit_price": null, "strength_mg": 0.25, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE 2MG/2ML 10 INH. NEBULES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 214.25, "pack_count": null, "unit_price": null, "strength_mg": 2.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RHINORELIEF NASAL SUSP. 50 MCG/METERED SPRAY DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "irritable-airways" } ] }