{
  "schema_version": 1,
  "kind": "condition",
  "id": "irritability-or-anger",
  "name": "Irritability or Anger",
  "category": "chronic",
  "sources": "Agitation - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK493153/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) - condition scope only, no dose · No dose - no medicine is given for this in primary care",
  "review_status": "reviewed",
  "verified_against": "No dose - no medicine is given for this in primary care · Irritability or Anger - disease-level clinical article (irritability-or-anger-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 1066,
      "generic": "No drug therapy in primary care (Assessment & Advice)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "A normal emotional state or behaviour reported by the patient, not itself a mental disorder; the GP explores triggers such as stress, poor sleep, substance use, or an underlying mood or anxiety disorder, and manages the cause rather than the symptom directly.",
      "adult_duration": "Assessment and advice",
      "dose_source": "No dose - no medicine is given for this in primary care",
      "rationale": "A normal emotional state or behaviour reported by the patient, not itself a mental disorder; the GP explores triggers such as stress, poor sleep, substance use, or an underlying mood or anxiety disorder, and manages the cause rather than the symptom directly.",
      "cautions": [
        "RED FLAG - Expressed explicit intent or plans for domestic violence, assault, homicide, or self-harm: assess urgently and refer.",
        "No medicine is prescribed for this in primary care. The value of the consultation is recognition, explanation and follow-up, and referral if the red flags above appear.",
        "RED FLAG - Agitation/severe irritability requires prioritizing the diagnosis and treatment of acute underlying medical conditions while ensuring safety.",
        "RED FLAG - Antipsychotic monotherapy should be avoided for agitation due to alcohol withdrawal as it can lead to delirium tremens.",
        "RED FLAG - Irritability as part of a manic episode (elevated mood, decreased need for sleep, grandiosity) needing urgent psychiatric assessment."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children follow the same pathway: assessment, explanation and follow-up. No primary-care medicine is implied.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "irritability-or-anger"
    }
  ]
}