Intertrigo

Apply protective barrier cream to clean dry skin folds twice daily - until skin fold irritation resolves

Apply to clean dry skin folds in children

No labelled dose - barrier preparation applied to intact skin, to effect

Barrier protectant that shields irritated skin-fold surfaces from the friction and trapped moisture that cause intertrigo in the first place, rather than treating an infection. Addresses the mechanical cause described in the cautions.

Apply to affected area twice daily x 2-4 weeks (continue 1 week after resolution)

Egyptian National Drug Formulary - Antimicrobial 2023 (clotrimazole monograph)

Topical imidazole antifungal that disrupts the fungal cell membrane, used when intertrigo becomes secondarily infected with Candida (the fiery red rash with satellite pustules noted in the cautions).

Apply 2% ointment to the affected fold twice daily - Until the rash resolves

Applied the same way in children - a topical dose is not weight-based. The formulary's paediatric instruction is a small amount three times daily for 5 to 10 days, with review at 5 days if there is no clinical response (Egyptian National Drug Formulary, mupirocin monograph).

Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) for the indication - verbatim: "Topical treatments such as mupirocin or bacitracin may be effective for lesions infected with mild bacteria." Dose from the same article, the sentence that governs its topical options: "Topical treatments should be applied twice daily until the rash resolves." The 2% strength is the only mupirocin marketed in Egypt.

The antibacterial for a fold that has become mildly infected rather than simply macerated. It is the option the source names first, and the one of the two named that is sold plain in Egypt.

250 mg orally four times daily; the dose may be doubled for a severe infection - The formulary states no course length for this dose - review at 5 to 7 days rather than repeating a prescription

Age-banded rather than weight-based by mouth: 1 month to 1 year 62.5 to 125 mg, 2 to 9 years 125 to 250 mg, 10 years and older 250 to 500 mg, all four times daily (Egyptian National Drug Formulary, flucloxacillin monograph, quoting BNFC for beta-lactamase-producing staphylococcal infection including impetigo and cellulitis).

Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) for the indication - verbatim: "Flucloxacillin or erythromycin, which targets gram-positive bacteria such as Staphylococcus or Streptococcus, should be prescribed if oral medication is necessary." Dose from Egyptian National Drug Formulary - Antimicrobial 2023, flucloxacillin monograph - verbatim: "The usual adult dose orally or by intramuscular injection is 250 mg four times daily" and "All systemic doses may be doubled in severe infections."

Oral cover when the fold is infected beyond what a cream reaches. Erythromycin is named alongside it in the source and cannot be dispensed in Egypt, which leaves this as the source's usable oral option.

100 to 200 mg orally once daily x 7 days

The source states this 7-day course for adults and gives no weight-based equivalent, so none is stated here.

Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) - verbatim, indication and dose in one sentence: "For resistant fungal infections, oral fluconazole at a dosage of 100 to 200 mg daily for 7 days may be effective."

For candidal intertrigo that has not settled on a topical antifungal. The source offers it for resistant fungal infection, which makes it a second step rather than a first.

Apply 1% cream sparingly to the affected skin two or three times daily after gently cleansing the area - Short course only - the label limits courses in children to seven to ten days

Same application in children, but the label caps the course at seven to ten days.

Hydrocortisone Cream 1% w/w SmPC sections 4.1 and 4.2 (eMC product 13103) - verbatim indication, which names this condition: "Hydrocortisone Cream is indicated for the treatment of eczema and dermatitis of all types, including atopic eczema, photodermatitis, otitis externa, primary irritant and allergic dermatitis, intertrigo, prurigo nodularis, seborrhoeic dermatitis and insect bite reactions." Dose, verbatim: "Adults and children: To be applied sparingly to the affected skin two or three times daily after gently cleansing the area. Courses of treatment in children should generally be limited to not more than seven to ten days." Clinical framing from Intertrigo - StatPearls - NCBI Bookshelf (NBK531489) - disease-level clinical article (intertrigo-full.txt) - verbatim: "Low-dose steroids, such as hydrocortisone cream, can be considered for their anti-inflammatory properties, although they are not always necessary."

An add-on for the itch and redness while something else treats the cause. The source is explicit that it is optional, and its licence names intertrigo directly.