{
  "schema_version": 1,
  "kind": "condition",
  "id": "idiopathic-photodermatosis",
  "name": "Idiopathic photodermatosis",
  "category": "acute",
  "sources": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef · Levocetirizine dihydrochloride tablets US prescribing information, sections 1 and 2 Dosage and Administration (DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef) · Sathe NC, Ramsey ML. Polymorphic Light Eruption. [Updated 2026 Feb 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID: NBK430886. PMID: 28613636.",
  "review_status": "reviewed",
  "verified_against": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 994,
      "generic": "Levocetirizine",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 5.0,
      "adult_dose": "5 mg PO once daily in evening (2.5 mg once daily may suffice).",
      "adult_duration": null,
      "dose_source": "DailyMed SetID 8274ca80-e7d3-4f4f-9901-cc5c589b4fef sections 1 and 2.2, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8274ca80-e7d3-4f4f-9901-cc5c589b4fef",
      "rationale": "Standard second-generation antihistamine dose for the itch of polymorphic light eruption/idiopathic photodermatosis; dosing does not change with the trigger for the itch.",
      "cautions": [
        "Rule out lupus erythematosus or porphyria as an underlying cause if the eruption is recurrent or atypical.",
        "Evening dosing suits itch that is often worse at night.",
        "Do not combine with cetirizine - levocetirizine is cetirizine's active component, so together they double the dose.",
        "Reduce to 2.5 mg in mild renal impairment.",
        "Treats itch only; if the eruption is recurrent or atypical, investigate for an underlying cause such as lupus erythematosus or porphyria rather than relying on the antihistamine.",
        "Contraindicated in end-stage renal disease (CLcr <10 mL/min) and hemodialysis."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Age 6-11y: 2.5 mg (1/2 scored tablet) PO once daily in evening; age <6y: use oral solution.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": [
        {
          "label": "6 to 11 years",
          "age_min_months": 72,
          "age_max_months": 143,
          "dose_text": "2.5 mg once daily in the evening"
        }
      ],
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "ZALKEVOR 5 MG 10 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL-OBOUR > REPHARMA",
          "price_egp": 5.5,
          "pack_count": 10,
          "unit_price": 0.55,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "RHIPGIC 5 MG 30 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "P & C LABS",
          "price_egp": 19.5,
          "pack_count": 30,
          "unit_price": 0.65,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LERGOPAN 5 MG 10 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 7.5,
          "pack_count": 10,
          "unit_price": 0.75,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LEVOCITRONE 5 MG 10 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGYPHAR",
          "price_egp": 21.0,
          "pack_count": 10,
          "unit_price": 2.1,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "RAMATRIZINE  5 MG 30 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGPI > RAMAPHARMA",
          "price_egp": 96.0,
          "pack_count": 30,
          "unit_price": 3.2,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LEVOHISTAM 5 MG 30 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGPI > UTOPIA",
          "price_egp": 117.0,
          "pack_count": 30,
          "unit_price": 3.9,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ARAXILEVE 5 MG 30 ORO-DISPERSIBLE TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS > ARAX PHARM. IND.",
          "price_egp": 51.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "LEVCET 5MG 20 ORODISSOLVABLE TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)",
          "price_egp": 85.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 5.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MERVOZA 2.5MG/5ML SYRUP 120 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL NAPI PHARMACEUTICALS",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 2.5,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MODALLERGE 0.5MG/ML ORAL SOL.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EGPI > MODERN PHARMA",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 0.5,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "idiopathic-photodermatosis"
    }
  ]
}