{
  "schema_version": 1,
  "kind": "condition",
  "id": "herpes-labialis",
  "name": "Herpes labialis (cold sores)",
  "category": "infectious",
  "sources": "Egyptian National Drug Formulary - Antimicrobial 2023 (acyclovir monograph)",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 (acyclovir monograph)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 926,
      "generic": "Acyclovir",
      "line": 1,
      "is_adjunct": false,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Apply 5 times daily (every 4 hours) to affected skin",
      "adult_duration": "4 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (acyclovir monograph)",
      "rationale": "Nucleoside analogue antiviral that is selectively activated in infected cells to block viral DNA replication, applied topically at the first sign of a cold-sore recurrence to shorten the episode.",
      "cautions": [
        "Apply at first sign of prodromal tingling or redness.",
        "Wash hands before and after application to prevent autoinoculation.",
        "Avoid contact with eyes."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Topical cream: Apply 5 times daily for 4 days in immunocompetent children ≥12 years of age",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "VIRUSTAT 5% CREAM 5 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 13.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 5000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ACYCLOSTAD 5% CREAM 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > STADA",
          "price_egp": 23.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ACYCLOVIR-MISR 5% TOPICAL CREAM 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR",
          "price_egp": 23.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "VIRUSTAT 5% CREAM 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHAROPHARMA",
          "price_egp": 23.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ZOVIRAX 5% TOPICAL CREAM 10 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLAXO SMITHKLINE",
          "price_egp": 27.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 10000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "herpes-labialis"
    }
  ]
}