# Head Lice (pediculosis capitis)

- Category: infectious
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414): "Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single application is generally sufficient; however, may repeat 7 days after first treatment if lice or nits are still present." The formulary's head lice strength is 1% against the 2.5% given here, and it puts 5% at scabies. · AAP Clinical Report: Head Lice 2022 · CDC Parasites: Lice: Head Lice Treatment 2020 · Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)
- Verified date: 2026-08

## Verified against

- AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414): "Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single application is generally sufficient; however, may repeat 7 days after first treatment if lice or nits are still present." The formulary's head lice strength is 1% against the 2.5% given here, and it puts 5% at scabies.
- AAP Clinical Report: Head Lice 2022
- Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)

## Treatment metadata

- Permethrin — topical
- Malathion — topical

## Complete treatment card

```text
HEAD LICE (PEDICULOSIS CAPITIS)
Sources: AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian
         National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414):
         "Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with
         conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of
         lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes (but
         no longer), then rinse off with warm water; remove remaining nits with a nit comb. A single
         application is generally sufficient; however, may repeat 7 days after first treatment if
         lice or nits are still present." The formulary's head lice strength is 1% against the 2.5%
         given here, and it puts 5% at scabies. · AAP Clinical Report: Head Lice 2022 · CDC
         Parasites: Lice: Head Lice Treatment 2020 · Ovide (malathion) Lotion 0.5% US prescribing
         information (DailyMed, Taro)
Review status: REVIEWED against 3 sources listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (2)
    - Itching is the main presenting complaint of a lice infestation  [itching]
    - Itching in someone living in crowded or unhygienic conditions raises suspicion for body lice
      [itching]
  SIGNS - what you find (4)
    - Diagnosis is confirmed by seeing at least one live louse on examination
    - Nits alone do not confirm active infestation, since they can persist on hair for months after
      treatment
    - Dandruff, hairspray residue, and dirt can look like nits and cause false positives
    - Pubic lice are diagnosed by finding lice in the pubic hair itself
  TESTS (4)
    - Sticky tape can collect adult lice from the scalp for microscopic examination
    - Nits look oval and are firmly attached to the hair shaft
    - A Wood lamp makes nits fluoresce greenish-yellow
    - Skin scrapings can rule out a fungal infection when the diagnosis is uncertain
  IF NOT THIS - what else fits (6)
    - Scalp lice must be differentiated from dandruff
    - Scalp lice must be differentiated from seborrhea
    - Scalp lice must be differentiated from superficial fungal infection
    - Scalp lice must be differentiated from eczema
    - Scalp lice must be differentiated from folliculitis
    - Scalp lice must be differentiated from scabies
  Source  StatPearls "Pediculosis" - disease-level clinical article
  Status  traced to the source above

1. PERMETHRIN                                             [1st line]
   Adult    Apply 2.5% lotion or cream to clean, towel-dried hair and scalp, leave on for 10
            minutes, then rinse thoroughly with warm water. Repeat application in 7-10 days. x 2
            applications 7-10 days apart
   Peds     Suitable for infants and children >=2 months old. Apply to scalp/hair, leave on for 10
            minutes, rinse. Repeat in 7-10 days.
   Source   AAP Clinical Report: Head Lice 2022 for the indication, with the product from Egyptian
            National Drug Formulary - Antimicrobial 2023, Permethrin monograph (printed page 414):
            "Head lice: Topical: Cream rinse/lotion 1%: Prior to application, wash hair with
            conditioner-free shampoo; rinse with water and towel dry. Apply a sufficient amount of
            lotion or cream rinse to saturate the hair and scalp ... Leave on hair for 10 minutes
            (but no longer), then rinse off with warm water; remove remaining nits with a nit comb.
            A single application is generally sufficient; however, may repeat 7 days after first
            treatment if lice or nits are still present." The formulary's head lice strength is 1%
            against the 2.5% given here, and it puts 5% at scabies.
   Why      AAP/CDC guidelines specify 1% permethrin baseline; Ectomethrin 2.5% lotion/cream is the
            registered formulation available in Egyptian retail pharmacies.
   Caution  Avoid contact with eyes and mucous membranes; rinse thoroughly with water if contact
            occurs.
            Re-treatment on day 7-10 is essential to kill newly hatched nits, as topical
            pediculicides are not completely ovicidal.
            Examine and treat all household members with active infestation simultaneously to
            prevent re-infestation.
   Egypt    ECTOMETHRIN 2.5 % CREAM 20 GM    MISR > APC (A...    12.00 EGP
            ECTOMETHRIN 5 % CREAM. 20 GM     MISR > APC (A...    21.00 EGP
            ECTOMETHRIN 5% OINT. 20 GM       MISR > APC (A...    21.00 EGP
            NEWCID 1% 60ML SHAMPOO           CID                  9.00 EGP
            NEWCID 1% 80ML SHAMPOO           CID                 11.00 EGP

2. MALATHION                                              [2nd line]
   Adult    Apply 0.5% lotion to dry hair and scalp, allow to air dry naturally, leave on for 8-12
            hours (or overnight), then wash out with shampoo. Repeat in 7-9 days if live lice
            persist. x 1-2 applications 7-9 days apart
   Peds     Approved for children >=6 months (BNFC 2024) or >=6 years (CDC 2020 / FDA). Apply to dry
            hair, leave for 8-12 hours, then shampoo out. Repeat in 7-9 days.
   Source   Ovide (malathion) Lotion 0.5% US prescribing information (DailyMed, Taro)
   Why      Second-line organophosphate pediculicide registered in Egypt (Prioderm / Lice Clean 0.5%
            lotion) used when permethrin treatment failure or resistance occurs
   Caution  Flammable due to isopropyl alcohol base; keep away from open flames, heat sources, and
            electric hair dryers while applied.
            Do not use in infants under 6 months of age without specialist advice.
            May cause temporary scalp irritation or stinging.
            Leave the hair uncovered while it dries, and comb it through with a fine nit comb after
            rinsing - the lotion kills, the comb removes.
            It is an organophosphate. If a child swallows any, that is an immediate hospital trip,
            not a wait.
   Egypt    PRIODERM  0.5 % LOTION 60 ML     PHARCO > MUND...     8.00 EGP
                -> ? different route - not topical
            LICE CLEAN 0.5GM/100ML TOPICAL LOTION WESTERN PHARMACEUTICALS INDUSTRIES...     8.00 EGP
                -> ? different route - not topical

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
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