{
  "schema_version": 1,
  "kind": "condition",
  "id": "gingivitis",
  "name": "Gingivitis",
  "category": "infectious",
  "sources": "Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529) · Egyptian National Drug Formulary - Antimicrobial 2023 (phenoxymethylpenicillin monograph, odontogenic infection) · Metronidazole 200 mg Tablets SmPC section 4.2, acute ulcerative gingivitis (eMC product 12348) · Daley JO, Jain P. Gingivitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan- . [Updated 2026 Jun 7]. Bookshelf ID: NBK557422. PMID: 32491354.",
  "review_status": "reviewed",
  "verified_against": "Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529) · Metronidazole 200 mg Tablets SmPC section 4.2, acute ulcerative gingivitis (eMC product 12348) · Egyptian National Drug Formulary - Antimicrobial 2023 (phenoxymethylpenicillin monograph, odontogenic infection) · Daley JO, Jain P. Gingivitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan- . [Updated 2026 Jun 7]. Bookshelf ID: NBK557422. PMID: 32491354.",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 835,
      "generic": "Chlorhexidine",
      "line": 1,
      "is_adjunct": false,
      "form": "mouth",
      "strength_mg": null,
      "adult_dose": "Rinse with 10 mL of 0.2% mouthwash for 1 minute twice daily",
      "adult_duration": "About one month for gingivitis, then review - the label sets that course length and expects the response to vary",
      "dose_source": "Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529)",
      "rationale": "Chlorhexidine suppresses the plaque bacteria that drive the gum inflammation, and gingivitis is a labelled indication for it. It buys control while the plaque itself is dealt with; it is not a substitute for scaling and brushing.",
      "cautions": [
        "This treats the inflammation, not the cause. Plaque removal by a dentist is the definitive treatment, and gums that keep bleeding despite good brushing need scaling.",
        "Brown staining of the teeth and tongue is expected with courses of this length. It is reversible and comes off with dental cleaning, but warn the patient first or they will stop the treatment.",
        "Taste is dulled while using it, and it can sting a sore mouth.",
        "Toothpaste inactivates chlorhexidine. Rinse the mouth with water and leave a gap after brushing, rather than using them together.",
        "Gums that bleed easily along with bruising, or with any other unexplained bleeding, is a blood problem until proved otherwise - check a full blood count."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Not for routine use in young children, who swallow mouthwash rather than spitting it out. Bleeding gums in a child are usually plaque or an erupting tooth - a dentist, not a mouthwash.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "ANTISEPTOL 1MG/ML MOUTH WASH 120 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KAHIRA",
          "price_egp": 9.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 1.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "HEXITOL 1.25MG/ML MOUTH WASH 100 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 49.9,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 1.25,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "gingivitis"
    },
    {
      "id": 836,
      "generic": "Metronidazole",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": null,
      "adult_dose": "200 mg three times daily",
      "adult_duration": "3 days",
      "dose_source": "Metronidazole 200 mg Tablets SmPC section 4.2, acute ulcerative gingivitis (eMC product 12348)",
      "rationale": "For acute necrotising ulcerative gingivitis only - the painful, punched-out, bleeding interdental papillae with foul breath. That is an anaerobic infection and metronidazole is what covers it. Ordinary gingivitis needs no antibiotic.",
      "cautions": [
        "The antibiotic alone will not cure ANUG. It needs dental debridement; without it the disease comes straight back.",
        "Facial swelling, trismus or fever is a spreading odontogenic infection, not gingivitis - that needs same-day dental or maxillofacial referral.",
        "Egypt does not sell a 200 mg metronidazole tablet - the packs are 250 mg and 500 mg. The 200 mg above is the label's dose; giving 250 mg three times daily for 3 days is the substitution Egyptian practice makes, and that is a prescriber's decision rather than a labelled dose.",
        "A metallic taste and furred tongue are common and not a reason to stop.",
        "ANUG in a young adult who is otherwise well is usually smoking, stress and poor oral hygiene. ANUG that recurs or is severe should prompt an HIV test.",
        "Strictly avoid alcohol and propylene glycol-containing products during treatment and for 3 days (72 hours) after the last dose - Egyptian National Drug Formulary, Antimicrobial 2023."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "The label gives age bands for acute ulcerative gingivitis, all for 3 days: 7-10 years 100 mg three times daily; 3-7 years 100 mg twice daily; 1-3 years 50 mg three times daily.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "TRICHOGYL 250 MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NASR",
          "price_egp": 4.35,
          "pack_count": 20,
          "unit_price": 0.22,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DUMOZOL 500MG 20 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MINA PHARM > ALPHARMA-DENMARK",
          "price_egp": 7.0,
          "pack_count": 20,
          "unit_price": 0.35,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLAGICURE 250MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KAHIRA",
          "price_egp": 7.0,
          "pack_count": 20,
          "unit_price": 0.35,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "METRONIDAZOLE-MUP 250 MG 20 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MUP",
          "price_egp": 11.0,
          "pack_count": 20,
          "unit_price": 0.55,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "METROZOLE 250MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MEMPHIS",
          "price_egp": 20.0,
          "pack_count": 20,
          "unit_price": 1.0,
          "strength_mg": 250.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "TRICHOGYL 500MG 12 F.C.TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NASR",
          "price_egp": 15.0,
          "pack_count": 12,
          "unit_price": 1.25,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "GEDAZOLE 500MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS",
          "price_egp": 34.0,
          "pack_count": 20,
          "unit_price": 1.7,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "METROGYPTON 500 MG 20 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GYPTO PHARMA",
          "price_egp": 34.0,
          "pack_count": 20,
          "unit_price": 1.7,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "DUMOZOL 125MG/5ML SUSP. 125ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MINA PHARM > ALPHARMA-DENMARK",
          "price_egp": 5.75,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 125.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "METROZOLE 125MG/5ML SUSP. 120 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MEMPHIS",
          "price_egp": 19.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 125.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "gingivitis"
    },
    {
      "id": 837,
      "generic": "Phenoxymethyl penicillin",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "500 mg every 6 to 8 hours for 5 to 7 days in combination with metronidazole",
      "adult_duration": "5-7 days",
      "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (phenoxymethylpenicillin monograph, odontogenic infection)",
      "rationale": "The Egyptian formulary pairs this with metronidazole for acute gingivitis of dental origin. It is a narrow-spectrum Access-group penicillin, which is the right first choice when an antibiotic is genuinely needed in the mouth.",
      "cautions": [
        "Take on an empty stomach - 1 hour before or 2 hours after food - or absorption drops.",
        "Penicillin allergy is an absolute contraindication. Ask before prescribing, every time.",
        "This is given with metronidazole, not instead of it.",
        "Most gingivitis needs no antibiotic whatsoever. Reach for this only when there is necrotising disease or a spreading dental infection."
      ],
      "peds_mgkg_low": 25.0,
      "peds_mgkg_high": 50.0,
      "peds_max_mg": 2000.0,
      "peds_basis": "day",
      "peds_unit": "mg",
      "peds_note": "25 to 50 mg/kg/day in divided doses every 6 hours; maximum daily dose 2,000 mg/day.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 250,
          "high_mg": 500,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 500,
          "high_mg": 1000,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 750,
          "high_mg": 1500,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 1000,
          "high_mg": 2000,
          "capped": false
        }
      ],
      "brands": [
        {
          "trade_name": "OSPEN 1.0 MIU 12 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SANDOZ",
          "price_egp": 24.0,
          "pack_count": 12,
          "unit_price": 2.0,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "OSPEN 1.5 MIU 12 F.C.TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SANDOZ",
          "price_egp": 41.0,
          "pack_count": 12,
          "unit_price": 3.42,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "gingivitis"
    }
  ]
}