{ "schema_version": 1, "kind": "condition", "id": "giardiasis", "name": "Giardiasis", "category": "infectious", "sources": "ALINIA (nitazoxanide) US prescribing information, section 2.1 Recommended Dosage, Table 1 (DailyMed SetID e90f98d9-3c9b-4e75-ba18-5517283eadf0) · WHO Parasitic Diseases 2021 · Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph) · Tindamax (tinidazole) US prescribing information, Dosage and Administration - Giardiasis (DailyMed, Mission Pharmacal)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph) · Tindamax (tinidazole) US prescribing information, Dosage and Administration - Giardiasis (DailyMed, Mission Pharmacal) · ALINIA (nitazoxanide) US prescribing information, section 2.1 Recommended Dosage, Table 1 (DailyMed SetID e90f98d9-3c9b-4e75-ba18-5517283eadf0) · Giardiasis - disease-level clinical article (giardiasis-clinical.txt)", "verified_date": "2026-08", "treatments": [ { "id": 832, "generic": "Metronidazole", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 250.0, "adult_dose": "250-500 mg TID for 5-7 days or single 2 g daily dose for 3 days", "adult_duration": "3-7 days", "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (metronidazole monograph)", "rationale": "Nitroimidazole antiprotozoal that is activated inside the parasite to damage its DNA; the standard, inexpensive first-line treatment for giardiasis.", "cautions": [ "Avoid alcohol completely during treatment.", "Treat all household contacts if symptomatic.", "Nausea and metallic taste are common." ], "peds_mgkg_low": 15.0, "peds_mgkg_high": 30.0, "peds_max_mg": 1200.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "Divided TID for 5-7 days", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 150, "high_mg": 300, "capped": false }, { "weight_kg": 20, "low_mg": 300, "high_mg": 600, "capped": false }, { "weight_kg": 30, "low_mg": 450, "high_mg": 900, "capped": false }, { "weight_kg": 40, "low_mg": 600, "high_mg": 1200, "capped": false } ], "brands": [ { "trade_name": "TRICHOGYL 250 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 4.35, "pack_count": 20, "unit_price": 0.22, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLAGICURE 250MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 7.0, "pack_count": 20, "unit_price": 0.35, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRICHOCID 250MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 7.0, "pack_count": 20, "unit_price": 0.35, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "METRONIDAZOLE-MUP 250 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 11.0, "pack_count": 20, "unit_price": 0.55, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AMRIZOLE 250 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 20.0, "pack_count": 20, "unit_price": 1.0, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "METROZOLE 250MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 20.0, "pack_count": 20, "unit_price": 1.0, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DUMOZOL 125MG/5ML SUSP. 125ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > ALPHARMA-DENMARK", "price_egp": 5.75, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "METROZOLE 125MG/5ML SUSP. 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "giardiasis" }, { "id": 833, "generic": "Tinidazole", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "2 g single dose taken with food", "adult_duration": "single-dose", "dose_source": "Tindamax (tinidazole) US prescribing information, Dosage and Administration - Giardiasis (DailyMed, Mission Pharmacal)", "rationale": "Nitroimidazole in the same class as metronidazole but with a longer half-life allowing a shorter course, offered as an alternative for patients wanting a simpler regimen.", "cautions": [ "Avoid alcohol during and for 3 days after dose.", "Take with food.", "The label licenses the paediatric single dose from 3 years, not below.", "Not in the first trimester of pregnancy. Later in pregnancy weigh it case by case, and stop breastfeeding for the dose and 3 days after - it stays in milk that long." ], "peds_mgkg_low": 50.0, "peds_mgkg_high": 50.0, "peds_max_mg": 2000.0, "peds_basis": "dose", "peds_unit": "mg", "peds_note": "Single dose with food", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": 36.0, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 500, "high_mg": 500, "capped": false }, { "weight_kg": 20, "low_mg": 1000, "high_mg": 1000, "capped": false }, { "weight_kg": 30, "low_mg": 1500, "high_mg": 1500, "capped": false }, { "weight_kg": 40, "low_mg": 2000, "high_mg": 2000, "capped": false } ], "brands": [ { "trade_name": "FASIGYN 500 MG 4 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PFIZER", "price_egp": 8.35, "pack_count": 4, "unit_price": 2.09, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PROTOZOLE 500 MG 12 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 39.0, "pack_count": 12, "unit_price": 3.25, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "giardiasis" }, { "id": 834, "generic": "Nitazoxanide", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500 mg BID with food", "adult_duration": "3 days", "dose_source": "ALINIA (nitazoxanide) US prescribing information, section 2.1 Recommended Dosage, Table 1 (DailyMed SetID e90f98d9-3c9b-4e75-ba18-5517283eadf0)", "rationale": "Antiprotozoal that interferes with the parasite's electron transfer enzyme system; a useful alternative to the nitroimidazoles, particularly convenient in Egypt where it is available as a paediatric suspension.", "cautions": [ "Take with food.", "Nitazoxanide is an excellent pediatric option available as suspension in Egypt.", "Urine discoloration can occur." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "100 mg BID (1-3 yrs) or 200 mg BID (4-11 yrs) with food for 3 days", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "1 to 3 years", "age_min_months": 12, "age_max_months": 47, "dose_text": "100 mg twice daily with food, for 3 days" }, { "label": "4 to 11 years", "age_min_months": 48, "age_max_months": 143, "dose_text": "200 mg twice daily with food, for 3 days" } ], "peds_doses": null, "brands": [ { "trade_name": "UNINITAPROZAX 500MG 12 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 16.0, "pack_count": 12, "unit_price": 1.33, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CRYPTOPER 500MG 30 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > TAG PHARMA", "price_egp": 56.0, "pack_count": 30, "unit_price": 1.87, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "XEROVIRINC 500MG 18 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM", "price_egp": 42.0, "pack_count": 18, "unit_price": 2.33, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PARAZOXANIDE 500 MG 18 CAP.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR > PHARMACARE", "price_egp": 63.0, "pack_count": 18, "unit_price": 3.5, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TRUSTNAL 500 MG 10 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 40.0, "pack_count": 10, "unit_price": 4.0, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NIT CLEAN 500MG 12 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA", "price_egp": 72.0, "pack_count": 12, "unit_price": 6.0, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CRYPTONAZ 500MG 12 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "COPAD PHARMA", "price_egp": 82.0, "pack_count": 12, "unit_price": 6.83, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NIT CLEAN 500MG 5*6 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA", "price_egp": 180.0, "pack_count": 6, "unit_price": 30.0, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "UNINITAPROZAX 100MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ZOLIFUTAL 100MG/5ML SUSP. 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI)", "price_egp": 13.5, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "giardiasis" } ] }