{
  "schema_version": 1,
  "kind": "condition",
  "id": "frozen-shoulder",
  "name": "Frozen Shoulder (Adhesive capsulitis)",
  "category": "chronic",
  "sources": "BESS Guidelines for Management of Frozen Shoulder 2015 · Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560) · Naproxen 500 mg Tablets SmPC section 4.2 (eMC product 2639)",
  "review_status": "reviewed",
  "verified_against": "Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560) · Naproxen 500 mg Tablets SmPC section 4.2 (eMC product 2639) · Adhesive Capsulitis (Frozen Shoulder) - disease-level clinical article (frozen-shoulder-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 781,
      "generic": "Ibuprofen",
      "line": 1,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 400.0,
      "adult_dose": "400 mg 3 times daily after meals",
      "adult_duration": null,
      "dose_source": "Ibuprofen 100 mg/5 ml SmPC section 4.2 (eMC product 4560)",
      "rationale": "Non-selective NSAID that controls the inflammatory pain of frozen shoulder, used alongside early gentle physiotherapy, which is the primary driver of recovery.",
      "cautions": [
        "Combines with early gentle physiotherapy within pain tolerance.",
        "Screen for underlying diabetes mellitus or thyroid dysfunction."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Rare condition in children; specialist referral needed",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "DAJUANOFEN 400 MG 20 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "COPAD PHARMA",
          "price_egp": 5.0,
          "pack_count": 20,
          "unit_price": 0.25,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FLABU 400MG 10 F.C.TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "DELTA PHARMA",
          "price_egp": 3.75,
          "pack_count": 10,
          "unit_price": 0.38,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NOVA-PROFEN 400MG 30 F.C. TABLETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SANOFI",
          "price_egp": 12.75,
          "pack_count": 30,
          "unit_price": 0.42,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "IBUPROFEN 400 MG 10 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SEDICO",
          "price_egp": 6.0,
          "pack_count": 10,
          "unit_price": 0.6,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "MAFO 400 MG  30 F.C.TABS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EIPICO",
          "price_egp": 42.0,
          "pack_count": 30,
          "unit_price": 1.4,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BRUFEN 400 MG 30 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "KAHIRA > ABBOTT LABORATORIES",
          "price_egp": 78.0,
          "pack_count": 30,
          "unit_price": 2.6,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PROFUSOL 400MG 20 S.G CAPS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.",
          "price_egp": 31.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ANALGIPROF 400 MG 25 SACHETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EVA PHARMA",
          "price_egp": 37.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 400.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NOVA-PROFEN  100MG/5ML ORAL SUSP. 100ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SANOFI",
          "price_egp": 2.25,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 100.0,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "BRUFEMOL-N SUSP. 60 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ARAB DRUG COMPANY (ADCO)",
          "price_egp": 4.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "frozen-shoulder"
    },
    {
      "id": 783,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Adhesive Capsulitis (Frozen Shoulder) - disease-level clinical article (frozen-shoulder-clinical.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "RED FLAG - New-onset arm weakness or numbness, or worsening symptoms, should prompt further medical evaluation as these suggest a diagnosis other than adhesive capsulitis (not just continued NSAID use)."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "frozen-shoulder"
    },
    {
      "id": 782,
      "generic": "Naproxen",
      "line": 2,
      "is_adjunct": false,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "500 mg twice daily after meals",
      "adult_duration": null,
      "dose_source": "Naproxen 500 mg Tablets SmPC section 4.2 (eMC product 2639)",
      "rationale": "Longer-acting NSAID alternative to ibuprofen for frozen shoulder, chosen when nocturnal pain persists between doses of a shorter-acting agent.",
      "cautions": [
        "Naproxen is a longer-acting NSAID alternative for persistent nocturnal pain.",
        "Refer for intra-articular steroid injection if pain prevents physiotherapy.",
        "Contraindicated in baseline creatinine clearance <30 ml/min and during the last trimester of pregnancy."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Specialist referral required",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "ORGOPROXEN 500 MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "ORGANOPHARMA > ORGANO",
          "price_egp": 16.0,
          "pack_count": 20,
          "unit_price": 0.8,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NAPROSYN 500 MG 10 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR > F.HOFFMAN LA ROCHE",
          "price_egp": 8.05,
          "pack_count": 10,
          "unit_price": 0.81,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NAPROFEN 500MG 10 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NILE.",
          "price_egp": 12.0,
          "pack_count": 10,
          "unit_price": 1.2,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "NAPROFEN 500MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EL NILE.",
          "price_egp": 24.0,
          "pack_count": 20,
          "unit_price": 1.2,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "frozen-shoulder"
    }
  ]
}