{
  "schema_version": 1,
  "kind": "condition",
  "id": "family-history-ovarian-cancer",
  "name": "Family history of ovarian cancer",
  "category": "chronic",
  "sources": "BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer - GeneReviews® - NCBI Bookshelf (NBK1247) - https://www.ncbi.nlm.nih.gov/books/NBK1247/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class AP66.02 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care",
  "review_status": "reviewed",
  "verified_against": "No dose - referral pathway, no medicine given in primary care · Family history of ovarian cancer - disease-level clinical article (family-history-ovarian-cancer-full.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 733,
      "generic": "No drug therapy in primary care (Referral & Advice)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "A risk factor, not a disease; the GP recognises it, discusses risk, and refers for genetic counselling/gynae-oncology assessment (e.g. BRCA testing) rather than prescribing.",
      "adult_duration": "Refer, with advice",
      "dose_source": "No dose - referral pathway, no medicine given in primary care",
      "rationale": "A risk factor, not a disease; the GP recognises it, discusses risk, and refers for genetic counselling/gynae-oncology assessment (e.g. BRCA testing) rather than prescribing.",
      "cautions": [
        "No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.",
        "The red flag symptoms of early ovarian cancer requiring urgent evaluation are persistent bloating, abdominal distention, early satiety, and pelvic masses.",
        "RED FLAG - Multiple affected relatives (ovarian and/or breast cancer), or a young age at a relative's diagnosis; personal symptoms (bloating, pelvic pain, early satiety) need urgent work-up."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children follow the same pathway: recognise and refer. No primary-care medicine is implied.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "family-history-ovarian-cancer"
    }
  ]
}