{ "schema_version": 1, "kind": "condition", "id": "facial-pain", "name": "Facial Pain", "category": "acute", "sources": "Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF p27) · Shankar Kikkeri N, Nagalli S. Trigeminal Neuralgia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; last update March 3, 2024.", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF p27) · Shankar Kikkeri N, Nagalli S. Trigeminal Neuralgia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; last update March 3, 2024.", "verified_date": "2026-08", "treatments": [ { "id": 726, "generic": "Carbamazepine", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": null, "adult_dose": "Initial 200-400 mg daily, increased gradually until pain-free, usually 200 mg 3-4 times daily; up to 1200 mg daily may be needed in some cases, then tapered to the lowest possible dose that maintains control. Elderly: initial 100 mg twice daily.", "adult_duration": "As directed; long-term at the lowest effective maintenance dose once pain is controlled.", "dose_source": "Egyptian National Drug Formulary - nervous-2025.pdf, Carbamazepine monograph (chapter PDF p27)", "rationale": "Carbamazepine is the guideline first-line drug specifically for trigeminal neuralgia, one of the recognised causes within the broad 'facial pain' symptom code; it is not appropriate for facial pain from other causes.", "cautions": [ "Only appropriate for the specific pattern of trigeminal neuralgia (brief, electric-shock-like, touch-triggered unilateral facial pain) - not for facial pain from dental, sinus, or other causes.", "There is a rare but serious risk of Stevens-Johnson syndrome/toxic epidermal necrolysis and agranulocytosis - stop immediately and seek care if rash or fever develops.", "Many drug interactions (it is a strong enzyme inducer) - check other medications.", "Avoid in pregnancy where possible - associated with neural tube defects.", "Facial pain with jaw claudication or visual change in an older adult needs urgent referral for possible giant cell arteritis, not carbamazepine.", "Facial swelling or fever suggests a dental/sinus abscess needing antibiotics and dental/ENT referral, not carbamazepine." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Trigeminal neuralgia is essentially an adult/older-adult condition; the formulary's paediatric carbamazepine dosing is for epilepsy, not facial pain, and is not reproduced here.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "CARBAMAZEPIN 200MG 10 TAB.U.S.P.33", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 3.0, "pack_count": 10, "unit_price": 0.3, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CARBAMAZEPINE 200MG XR 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 4.0, "pack_count": 10, "unit_price": 0.4, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TONOCLONE 200MG 30 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 13.5, "pack_count": 30, "unit_price": 0.45, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TONOCLONE RETARD 400MG C.R. 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 8.5, "pack_count": 10, "unit_price": 0.85, "strength_mg": 400.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CARBAPEX 200 MG CR 30 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MULTI-APEX", "price_egp": 81.0, "pack_count": 30, "unit_price": 2.7, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPIMAZEPINE CR 200 MG 10 CONTROLLED RELEASE F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 200.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NEUROTOP RETARD 300MG 100 S.R. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GEROT PHARMA > B.P PHARMA", "price_egp": 410.0, "pack_count": null, "unit_price": null, "strength_mg": 300.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NEUROTOP RETARD 600MG 100 S.R. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GEROT PHARMA > B.P PHARMA", "price_egp": 720.0, "pack_count": null, "unit_price": null, "strength_mg": 600.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALEXTOL 100MG/5ML ORAL SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": 100.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ARBATEG 2% SUSP. 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEDIZEN PHARMACEUTICAL INDUSTRIES", "price_egp": 35.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "facial-pain" } ] }