# Foreign Body in Eye

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Corneal Foreign Body - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK536977/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class FD37 - condition scope only, no dose · MSF Essential Drugs 2024 (oxybuprocaine 0.4% eye drops monograph) · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) · Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) · MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%. · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to two drops every two to four hours for the first two days, then four times daily, at all ages, with the course not to exceed ten days. · Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.
- Verified date: 2026-08

## Verified against

- Corneal Foreign Body - disease-level clinical article (eye-foreign-body-clinical.txt)
- MSF Essential Drugs 2024 (oxybuprocaine 0.4% eye drops monograph)
- Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353)
- Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931)
- MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%.
- Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to two drops every two to four hours for the first two days, then four times daily, at all ages, with the course not to exceed ten days.
- Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.

## Treatment metadata

- Benoxinate — eye
- Ofloxacin — eye
- Referral & safety-netting (no drug therapy)
- Hypromellose — eye

## Complete treatment card

```text
FOREIGN BODY IN EYE
Sources: Corneal Foreign Body - StatPearls - NCBI Bookshelf -
         https://www.ncbi.nlm.nih.gov/books/NBK536977/ · ICPC-3 (WONCA International Classification
         of Primary Care, 3rd edition) class FD37 - condition scope only, no dose · MSF Essential
         Drugs 2024 (oxybuprocaine 0.4% eye drops monograph) · Exocin 3 mg/ml Eye Drops (ofloxacin
         0.3%) SmPC section 4.2 (eMC product 1353) · Hypromellose ophthalmic solution, US over-the-
         counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) · MSF
         Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a
         named indication, dosed as up to 3 drops of the 0.4% single-use solution into the
         conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its
         other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all
         0.4%. · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one
         to two drops every two to four hours for the first two days, then four times daily, at all
         ages, with the course not to exceed ten days. · Hypromellose ophthalmic solution (Vista
         Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID
         00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as
         needed.
Review status: REVIEWED against Corneal Foreign Body - disease-level clinical article (eye-foreign-
               body-clinical.txt), MSF Essential Drugs 2024 (oxybuprocaine 0.4% eye
               drops monograph), Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC
               section 4.2 (eMC product 1353), Hypromellose ophthalmic solution, US
               over-the-counter label, Directions (DailyMed SetID
               00da365d-2988-9c9e-e063-6294a90a8931), MSF Essential Drugs 2024
               (oxybuprocaine eye drops monograph) - removal of foreign bodies is a
               named indication, dosed as up to 3 drops of the 0.4% single-use
               solution into the conjunctival sac, one to two minutes apart. Egypt
               registers the same molecule under its other international name,
               benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%.,
               Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC
               product 1353) - one to two drops every two to four hours for the
               first two days, then four times daily, at all ages, with the course
               not to exceed ten days., Hypromellose ophthalmic solution (Vista
               Gonio Eye Lubricant), US over-the-counter label, Directions
               (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or
               2 drops in the affected eye(s) as needed.  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (6)
    - Symptoms typically start suddenly, with ongoing discomfort that does not ease on its own
    - Patients report tearing, redness, a gritty sensation, pain whether the eye is open or shut,
      light sensitivity, and mild blurring without real vision loss  [eye discharge · photophobia ·
      redness]
    - A recent history of hammering, grinding, or similar work is common, and some patients can
      point to where it entered
    - Most patients misjudge exactly where the foreign body sensation is coming from  [foreign body]
    - The complaint is sudden discomfort, the feeling of something in the eye, redness, streaming
      tears and being unable to keep the eye open  [foreign body · redness]
    - Pain, dislike of light, watering and blurred vision are the rule, and infection or corneal
      scarring afterwards can cost the sight for good  [blurred vision · eye pain · photophobia ·
      scarring]
  SIGNS - what you find (6)
    - A foreign body retained over 24 hours can trigger white cells in the cornea or anterior
      chamber, and visible blood layering raises concern for a ruptured globe  [foreign body]
    - Redness is usually localized to the area right around the embedded material  [redness]
    - A metallic fragment can leave a rust deposit on the cornea
    - A positive Seidel sign shows fluid streaming from the injury site, pointing to a perforated
      globe
    - Look for a break in the corneal surface, the object itself, a swollen cornea, a rust ring
      where the fragment was metal, infiltrate in the front of the stroma, or a melting cornea
    - Red flag: if it has gone deeper it can cause uveitis after the injury, bleeding into the
      vitreous, or endophthalmitis  [bleeding]
  TESTS (6)
    - Fluorescein dye highlights corneal surface defects and hidden abrasions or debris
    - A plain x-ray is used when a metallic fragment is suspected but the exam does not confirm it
    - MRI should not be used when a metallic foreign body might be present
    - MRI is reserved for suspected nonmetallic material like wood or plastic, given its soft-tissue
      detail
    - A CBC with differential is checked if presentation is delayed or a deep eye infection is
      suspected
    - Corneal scrapings are Gram-stained, KOH-prepped, and cultured when organic material is
      involved
  IF NOT THIS - what else fits (8)
    - A simple corneal abrasion from trauma can mimic foreign body symptoms without any retained
      material
    - A corneal ulcer shows infiltration alongside the pain and photophobia
    - Branching dendritic ulcers on the cornea point to herpetic keratitis rather than a retained
      foreign body
    - Episodic surface defects with a prior history of similar erosion suggest recurrent corneal
      erosion
    - A raised pinguecula or pterygium growth can look like a lodged foreign body
    - A full-thickness globe rupture from the trauma needs emergency surgery to save vision
    - Acid or alkali chemical exposure needs immediate irrigation and is distinguished by that
      exposure history
    - A history of welding or sunlamp exposure points to UV keratitis rather than a retained foreign
      body
  Source  StatPearls "Corneal Foreign Body" - disease-level clinical article
  Status  traced to the source above

Rx: Topical anaesthetic, to examine and remove  |  Antibiotic prophylaxis after removal  |  Main
    treatment  |  Ocular lubricant while the surface heals

TOPICAL ANAESTHETIC, TO EXAMINE AND REMOVE
1. BENOXINATE                                             [1st line]
   Adult    Up to 3 drops of the 0.4% solution into the conjunctival sac, each one to two minutes
            apart. Anaesthesia starts within a minute and lasts 10 to 20 minutes. - One application
            at the time of the examination, and no more
   Peds     The same instillation in a child - a surface anaesthetic has no weight-based dose. The
            vial is single use and is discarded afterwards. A protective shield rather than a patch
            is sensible in a small child, because rubbing the anaesthetised eye is what does the
            damage.
   Source   MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies
            is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the
            conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its
            other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all
            0.4%.
   Why      The corneal foreign body article puts removal under topical anaesthesia and says a
            topical anaesthetic should be given for pain relief during the examination. MSF carries
            foreign-body removal as a named indication for the same drug and states the number of
            drops, so the use and the amount both come from documents that were opened.
   Caution  Never hand an anaesthetic eye drop to a patient to take home. MSF states that repeated
            use risks severe and permanent corneal damage, and the article records the same for
            topical tetracaine, reserving it to the first one to two hours. For pain after the
            procedure, give an oral analgesic - that is MSF's own instruction.
            Wait 15 minutes after instilling it before putting any other eye drop in.
            Refer the same day, before touching the eye, if the object is embedded or metallic, if
            the injury was high-velocity, or if globe penetration is possible.
            Check tetanus immunisation and give prophylaxis where it is due - the article singles
            out injuries involving organic foreign bodies.
   Egypt    BENOX 0.4% EYE DROPS 10 ML       EIPICO              23.00 EGP
            BOXINATE 0.4% EYE DROPS 10 ML    ALEXANDRIA          23.00 EGP
            SELECTOCAINE 0.4% EYE DROPS 10*0.5 ML SDU GLOBAL ADVANCED PHARMACEUTICAL...    40.00 EGP
            BENOXIDIA 0.4% EYE DROPS 30*0.5ML SDU ORCHIDIA                                 45.00 EGP


ANTIBIOTIC PROPHYLAXIS AFTER REMOVAL
2. OFLOXACIN                                              [1st line]
   Adult    1 to 2 drops of the 0.3% solution into the affected eye every 2 to 4 hours for the first
            2 days, then 4 times daily x 5 to 7 days, and never more than 10
   Peds     The label gives one dose for all ages: 1 to 2 drops every 2 to 4 hours for the first two
            days, then four times daily. Safety and effectiveness below one year of age are not
            established, and the label says data are very limited in neonates.
   Source   Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to
            two drops every two to four hours for the first two days, then four times daily, at all
            ages, with the course not to exceed ten days.
   Why      The corneal foreign body article calls for prophylactic broad-spectrum antibiotics such
            as fluoroquinolones after removal, reports that 90% of bacteria cultured from these
            injuries were sensitive to fluoroquinolone drops, and asks specifically for anti-
            pseudomonal cover in a contact lens wearer, which ofloxacin gives. Eight 0.3% ophthalmic
            products are marketed in Egypt.
   Caution  Stop and reassess rather than extending the course - the label caps it at ten days.
            An eye patch is contraindicated in a contact lens wearer and after an organic foreign
            body, because it raises the risk of infection; the article also reports a randomised
            trial in which patching changed neither time to comfort nor time to healing.
            A retained rust ring or a centrally placed foreign body needs ophthalmology within 24
            hours. A peripheral one with nothing retained can be reviewed in 2 to 3 days.
            Avoid in known quinolone hypersensitivity.
   Egypt    QUIFLURO 0.3% EYE DROPS 5 ML     PHAROPHARMA          6.00 EGP
            OFLOXIN 0.3% EYE DROPS 5 ML      KAHIRA               7.00 EGP
            OFLOXACIN 0.3% EYE DROPS 10 ML   SIGMA TEC            7.50 EGP
            OFLICIN 0.3% EYE DROPS 5 ML      MEMPHIS              8.00 EGP
            OFLOSWIX 0.3% EYE DROPS 5 ML     CHEMIPHARM          12.00 EGP
            OCUFLOX 0.3% EYE DROPS 5 ML      ALEXANDRIA          19.50 EGP
            OPTIFLOX 0.3% EYE DROPS 5 ML     JAMJOOM PHARM...    19.50 EGP
            OFLOX 0.3% EYE DROPS 5 ML        ALLERGAN > SO...    20.40 EGP


MAIN TREATMENT
3. REFERRAL & SAFETY-NETTING (NO DRUG THERAPY)            [1st line]
   Adult    A foreign object - commonly sand or dust in Cairo - on the surface of the eye; a GP can
            attempt simple removal and prescribe antibiotic drops afterward, referring if the object
            is embedded, metallic, or globe penetration is suspected. - Refer, with advice
   Peds     The drug rows above are instilled, not dosed by weight. The referral threshold and the
            safety-netting are the same at any age.
   Source   No dose - referral pathway, no medicine given in primary care
   Why      A foreign object - commonly sand or dust in Cairo - on the surface of the eye; a GP can
            attempt simple removal and prescribe antibiotic drops afterward, referring if the object
            is embedded, metallic, or globe penetration is suspected.
   Caution  The drug rows above are what the treating service gives. They are here so that the
            referral is an informed one and so the GP can recognise the regimen the patient comes
            back on - not as permission to start it without the referral.
            RED FLAG - MRI is strictly contraindicated if a metallic foreign body is suspected.
            RED FLAG - A visible metallic fragment or rust ring, an embedded or penetrating object
            or suspected rupture of the eyeball, or reduced vision after removal: refer urgently to
            ophthalmology.


OCULAR LUBRICANT WHILE THE SURFACE HEALS - give alongside
4. HYPROMELLOSE                                           [add-on - not a substitute]
   Adult    1 or 2 drops into the affected eye as needed - Until the surface has healed, usually a
            few days
   Peds     1 or 2 drops as needed, the same as an adult - a surface lubricant has no weight-based
            dose.
   Source   Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label,
            Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops
            in the affected eye(s) as needed.
   Why      The article's post-removal care is a prophylactic antibiotic, a cycloplegic for ciliary
            spasm and a lubricant, and it recommends lubricating drops or ointment to promote
            epithelial healing and ease discomfort. Four hypromellose products are marketed in
            Egypt.
   Caution  A lubricant eases discomfort. It does not replace the antibiotic cover or the follow-up
            examination.
            Wait 15 minutes after an anaesthetic drop before instilling anything else.
            Worsening pain, falling vision or a white spot on the cornea after removal means an
            ulcer until proven otherwise, and needs same-day ophthalmology.
   Egypt    HYDROBLEND 0.32% EYE DROPS 10*0.5 ML SDU GLOBAL ADVANCED PHARMACEUTICALS...    15.00 EGP
            GENTEAL EYE DROPS 10 ML          NOVARTIS > NO...    18.00 EGP
            OPTILUBRIC 0.32% EYE DROPS 30*0.5 ML SDU EVA PHARMA                            96.00 EGP
            HYDROBLEND 0.32% EYE DROPS 30*0.5 ML SDU GLOBAL ADVANCED PHARMACEUTICALS...   108.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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