{ "schema_version": 1, "kind": "condition", "id": "eye-foreign-body", "name": "Foreign Body in Eye", "category": "chronic", "sources": "Corneal Foreign Body - StatPearls - NCBI Bookshelf - https://www.ncbi.nlm.nih.gov/books/NBK536977/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class FD37 - condition scope only, no dose · MSF Essential Drugs 2024 (oxybuprocaine 0.4% eye drops monograph) · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) · Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) · MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%. · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to two drops every two to four hours for the first two days, then four times daily, at all ages, with the course not to exceed ten days. · Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.", "review_status": "reviewed", "verified_against": "Corneal Foreign Body - disease-level clinical article (eye-foreign-body-clinical.txt) · MSF Essential Drugs 2024 (oxybuprocaine 0.4% eye drops monograph) · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) · Hypromellose ophthalmic solution, US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) · MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%. · Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to two drops every two to four hours for the first two days, then four times daily, at all ages, with the course not to exceed ten days. · Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.", "verified_date": "2026-08", "treatments": [ { "id": 713, "generic": "Benoxinate", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "Up to 3 drops of the 0.4% solution into the conjunctival sac, each one to two minutes apart. Anaesthesia starts within a minute and lasts 10 to 20 minutes.", "adult_duration": "One application at the time of the examination, and no more", "dose_source": "MSF Essential Drugs 2024 (oxybuprocaine eye drops monograph) - removal of foreign bodies is a named indication, dosed as up to 3 drops of the 0.4% single-use solution into the conjunctival sac, one to two minutes apart. Egypt registers the same molecule under its other international name, benoxinate: BENOX, BOXINATE, SELECTOCAINE and BENOXIDIA, all 0.4%.", "rationale": "The corneal foreign body article puts removal under topical anaesthesia and says a topical anaesthetic should be given for pain relief during the examination. MSF carries foreign-body removal as a named indication for the same drug and states the number of drops, so the use and the amount both come from documents that were opened.", "cautions": [ "Never hand an anaesthetic eye drop to a patient to take home. MSF states that repeated use risks severe and permanent corneal damage, and the article records the same for topical tetracaine, reserving it to the first one to two hours. For pain after the procedure, give an oral analgesic - that is MSF's own instruction.", "Wait 15 minutes after instilling it before putting any other eye drop in.", "Refer the same day, before touching the eye, if the object is embedded or metallic, if the injury was high-velocity, or if globe penetration is possible.", "Check tetanus immunisation and give prophylaxis where it is due - the article singles out injuries involving organic foreign bodies." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "The same instillation in a child - a surface anaesthetic has no weight-based dose. The vial is single use and is discarded afterwards. A protective shield rather than a patch is sensible in a small child, because rubbing the anaesthetised eye is what does the damage.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "BENOX 0.4% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BOXINATE 0.4% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 23.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SELECTOCAINE 0.4% EYE DROPS 10*0.5 ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS", "price_egp": 40.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BENOXIDIA 0.4% EYE DROPS 30*0.5ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORCHIDIA", "price_egp": 45.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "eye-foreign-body" }, { "id": 714, "generic": "Ofloxacin", "line": 1, "is_adjunct": false, "form": "eye", "strength_mg": null, "adult_dose": "1 to 2 drops of the 0.3% solution into the affected eye every 2 to 4 hours for the first 2 days, then 4 times daily", "adult_duration": "5 to 7 days, and never more than 10", "dose_source": "Exocin 3 mg/ml Eye Drops (ofloxacin 0.3%) SmPC section 4.2 (eMC product 1353) - one to two drops every two to four hours for the first two days, then four times daily, at all ages, with the course not to exceed ten days.", "rationale": "The corneal foreign body article calls for prophylactic broad-spectrum antibiotics such as fluoroquinolones after removal, reports that 90% of bacteria cultured from these injuries were sensitive to fluoroquinolone drops, and asks specifically for anti-pseudomonal cover in a contact lens wearer, which ofloxacin gives. Eight 0.3% ophthalmic products are marketed in Egypt.", "cautions": [ "Stop and reassess rather than extending the course - the label caps it at ten days.", "An eye patch is contraindicated in a contact lens wearer and after an organic foreign body, because it raises the risk of infection; the article also reports a randomised trial in which patching changed neither time to comfort nor time to healing.", "A retained rust ring or a centrally placed foreign body needs ophthalmology within 24 hours. A peripheral one with nothing retained can be reviewed in 2 to 3 days.", "Avoid in known quinolone hypersensitivity." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "The label gives one dose for all ages: 1 to 2 drops every 2 to 4 hours for the first two days, then four times daily. Safety and effectiveness below one year of age are not established, and the label says data are very limited in neonates.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "QUIFLURO 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXIN 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 7.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOXACIN 0.3% EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA TEC", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLICIN 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 8.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOSWIX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CHEMIPHARM", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OCUFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPTIFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JAMJOOM PHARMACEUTICALS-K.S.A > JAMJOOM PHARMA", "price_egp": 19.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OFLOX 0.3% EYE DROPS 5 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALLERGAN > SOFICOPHARM", "price_egp": 20.4, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "eye-foreign-body" }, { "id": 716, "generic": "Referral & safety-netting (no drug therapy)", "line": 1, "is_adjunct": false, "form": null, "strength_mg": null, "adult_dose": "A foreign object - commonly sand or dust in Cairo - on the surface of the eye; a GP can attempt simple removal and prescribe antibiotic drops afterward, referring if the object is embedded, metallic, or globe penetration is suspected.", "adult_duration": "Refer, with advice", "dose_source": "No dose - referral pathway, no medicine given in primary care", "rationale": "A foreign object - commonly sand or dust in Cairo - on the surface of the eye; a GP can attempt simple removal and prescribe antibiotic drops afterward, referring if the object is embedded, metallic, or globe penetration is suspected.", "cautions": [ "The drug rows above are what the treating service gives. They are here so that the referral is an informed one and so the GP can recognise the regimen the patient comes back on - not as permission to start it without the referral.", "RED FLAG - MRI is strictly contraindicated if a metallic foreign body is suspected.", "RED FLAG - A visible metallic fragment or rust ring, an embedded or penetrating object or suspected rupture of the eyeball, or reduced vision after removal: refer urgently to ophthalmology." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "The drug rows above are instilled, not dosed by weight. The referral threshold and the safety-netting are the same at any age.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [], "condition_id": "eye-foreign-body" }, { "id": 715, "generic": "Hypromellose", "line": 1, "is_adjunct": true, "form": "eye", "strength_mg": null, "adult_dose": "1 or 2 drops into the affected eye as needed", "adult_duration": "Until the surface has healed, usually a few days", "dose_source": "Hypromellose ophthalmic solution (Vista Gonio Eye Lubricant), US over-the-counter label, Directions (DailyMed SetID 00da365d-2988-9c9e-e063-6294a90a8931) - instil 1 or 2 drops in the affected eye(s) as needed.", "rationale": "The article's post-removal care is a prophylactic antibiotic, a cycloplegic for ciliary spasm and a lubricant, and it recommends lubricating drops or ointment to promote epithelial healing and ease discomfort. Four hypromellose products are marketed in Egypt.", "cautions": [ "A lubricant eases discomfort. It does not replace the antibiotic cover or the follow-up examination.", "Wait 15 minutes after an anaesthetic drop before instilling anything else.", "Worsening pain, falling vision or a white spot on the cornea after removal means an ulcer until proven otherwise, and needs same-day ophthalmology." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "1 or 2 drops as needed, the same as an adult - a surface lubricant has no weight-based dose.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "HYDROBLEND 0.32% EYE DROPS 10*0.5 ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "GENTEAL EYE DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS > NOVARTIS SCIENTIFIC OFFICE", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPTILUBRIC 0.32% EYE DROPS 30*0.5 ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 96.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HYDROBLEND 0.32% EYE DROPS 30*0.5 ML SDU", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL ADVANCED PHARMACEUTICALS (GAP) > MONOPHARMA PHARMACEUTICALS", "price_egp": 108.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "eye-foreign-body" } ] }