Dawaa Reference

Clinical reference

Dysplastic Naevus (Atypical Mole)

Treatment options, dosing, cautions and Egyptian brands from the shipped Dawaa Reference card.

Evidence status

Checked against the sources named below

Sources3 sources

Dysplastic Nevi - StatPearls (NCBI Bookshelf NBK482210) - https://www.ncbi.nlm.nih.gov/books/NBK482210/ · ICPC-3 (WONCA International Classification of Primary Care, 3rd edition) class SD29.01 - condition scope only, no dose · No dose - referral pathway, no medicine given in primary care

Verified against1 document
  • No dose - referral pathway, no medicine given in primary care

Verified date2026-08

Presentation reference

Is it this?

Reference only, to read alongside your own examination.

Signs — what you find (4)

  • Nevi larger than 5 mm across with multiple colors - light brown, dark brown, pink - suggest a dysplastic nevus
  • A darker papular center with a lighter surrounding macular ring gives a fried-egg appearance [papules · rash]
  • Dysplastic nevi often show ABCDE features - asymmetry, border irregularity, color variation, diameter over 6 mm, and evolution
  • Dysplastic nevus syndrome is diagnosed when a patient has 5 or more atypical melanocytic nevi

Tests (3)

  • Complete excision by shave, punch, or excisional biopsy is recommended for a clinically suspicious lesion
  • Incisional biopsy is not recommended for a suspected dysplastic nevus
  • Dermoscopy cannot reliably distinguish a dysplastic nevus from melanoma in situ

If not this — what else fits (8)

  • Blue nevus
  • Basal cell carcinoma
  • Cutaneous melanoma
  • Dermatofibroma
  • A lentigo
  • Melanocytic nevi
  • Spitz nevus
  • Seborrheic keratosis

SourceStatPearls "Dysplastic Nevi" - disease-level clinical article

Presentation findings are traced to the source above.

1

NO DRUG THERAPY IN PRIMARY CARE (REFERRAL & ADVICE)

1st line
Adult dose and duration

An atypical pigmented mole with irregular borders and colour that can be difficult to distinguish from early melanoma and carries an increased melanoma risk, especially with multiple such moles; the GP refers for dermatology assessment with dermoscopy and possible excision rather than reassuring without review. - Refer, with advice

Paediatric dose

Children follow the same pathway: recognise and refer. No primary-care medicine is implied.

Dose source

No dose - referral pathway, no medicine given in primary care

Why

An atypical pigmented mole with irregular borders and colour that can be difficult to distinguish from early melanoma and carries an increased melanoma risk, especially with multiple such moles; the GP refers for dermatology assessment with dermoscopy and possible excision rather than reassuring without review.

Cautions
  • No medicine is prescribed for this in primary care - this entry is for recognition and referral. Anything given is decided by the service it is referred to.
  • RED FLAG - Any change in size, shape or colour, or a new symptom such as bleeding or itching, in an atypical mole needs urgent referral; multiple dysplastic naevi with a family history of melanoma need higher-risk surveillance.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.