{ "schema_version": 1, "kind": "condition", "id": "dyslipidemia", "name": "Dyslipidemia", "category": "chronic", "sources": "ESC/EAS Dyslipidaemias 2019 · Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) · Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) · Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430)", "review_status": "reviewed", "verified_against": "ESC/EAS Dyslipidaemias 2019 · Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph) · Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673) · Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430)", "verified_date": "2026-08", "treatments": [ { "id": 644, "generic": "Atorvastatin", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 20.0, "adult_dose": "10-20 mg once daily (any time of day), titrate up to 80 mg daily", "adult_duration": "long-term", "dose_source": "Atorvastatin 20 mg film-coated tablets SmPC section 4.2 Posology and method of administration (eMC product 13673)", "rationale": "HMG-CoA reductase inhibitor (statin) that lowers LDL cholesterol by blocking hepatic cholesterol synthesis, used to reduce cardiovascular risk in dyslipidemia.", "cautions": [ "CONTRAINDICATED in pregnancy and breastfeeding.", "Monitor LFTs before starting and at 12 months.", "Muscle pain requires creatine kinase check.", "Caution in heavy alcohol use or hepatic disease." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Specialist referral for pediatric familial hypercholesterolemia", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ANTICHOL 20 MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS", "price_egp": 14.4, "pack_count": 10, "unit_price": 1.44, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LIRIMAR 20 MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RIVA PHARMA S.A.E.", "price_egp": 15.0, "pack_count": 10, "unit_price": 1.5, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LIPOVAST 20MG 7 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 11.5, "pack_count": 7, "unit_price": 1.64, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SIGMALIP 20 MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA", "price_egp": 24.0, "pack_count": 10, "unit_price": 2.4, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LIPOSEDRA 20 MG 30 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DELTA PHARMA > SUECAL PHARMA", "price_egp": 111.0, "pack_count": 30, "unit_price": 3.7, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ATOR 20 MG 10 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 79.0, "pack_count": 10, "unit_price": 7.9, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ATCOLIPOX 20 MG 30 CHEW. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ATCO PHARMA", "price_egp": 72.0, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HIPOLIXAVAST 20 MG 30 CHEW. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI", "price_egp": 127.5, "pack_count": null, "unit_price": null, "strength_mg": 20.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "dyslipidemia" }, { "id": 645, "generic": "Rosuvastatin", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "5-10 mg once daily, titrate to 20-40 mg daily", "adult_duration": "long-term", "dose_source": "Rosuvastatin 10 mg film coated tablets SmPC section 4.2 Posology and method of administration (eMC product 14430)", "rationale": "Alternative HMG-CoA reductase inhibitor (statin) for LDL cholesterol lowering in dyslipidemia, chosen instead of atorvastatin based on individual tolerability, drug interactions, or the intensity of LDL lowering needed.", "cautions": [ "CONTRAINDICATED in pregnancy and breastfeeding.", "The 40 mg dose is contraindicated in severe renal impairment.", "Monitor LFTs and muscle symptoms.", "Caution in renal impairment." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Specialist referral in pediatric dyslipidemia", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "ROSUMOP 10MG 14 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > SANDOZ", "price_egp": 25.5, "pack_count": 14, "unit_price": 1.82, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VINAPOTEX 10 MG 14 F.C TABS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA EGYPT > AL ANSAR MARKETING COMPANY", "price_egp": 36.0, "pack_count": 14, "unit_price": 2.57, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NAPLEMA 10 MG 30 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NAPCO", "price_egp": 77.25, "pack_count": 30, "unit_price": 2.58, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ROSUVALING 10 MG 28 TABLETS", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UTOPIA PHARMA", "price_egp": 100.0, "pack_count": 28, "unit_price": 3.57, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NEXIROZOVA 10 MG 28 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ZETA PHARMA", "price_egp": 116.0, "pack_count": 28, "unit_price": 4.14, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "JUSTECHOL 10 MG 14 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AUG PHARMA", "price_egp": 74.0, "pack_count": 14, "unit_price": 5.29, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CRESTOR 10 MG 28 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "IPR PHARMACEUTICALS INCORPORATED > ASTRA ZENECA", "price_egp": 368.0, "pack_count": 28, "unit_price": 13.14, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EPIROVASTIN 10 MG 14 SCORED F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 56.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "dyslipidemia" }, { "id": 646, "generic": "Ezetimibe", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "10 mg once daily, monotherapy or add-on to statin", "adult_duration": "long-term", "dose_source": "ESC/EAS Dyslipidaemias 2019", "rationale": "Cholesterol absorption inhibitor that blocks intestinal uptake of dietary and biliary cholesterol; used as monotherapy or added to a statin when further LDL lowering is needed beyond what the statin achieves alone.", "cautions": [ "Monitor LFTs when combined with a statin.", "Caution in moderate to severe hepatic impairment.", "GI disturbance and fatigue have been reported." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Specialist referral in children", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "LOWTIMIB 10 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHAROPHARMA", "price_egp": 11.5, "pack_count": 10, "unit_price": 1.15, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CHOLSTOP 10MG 30 TAB", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 41.0, "pack_count": 30, "unit_price": 1.37, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EZETIMIBE 10MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BORG", "price_egp": 14.4, "pack_count": 10, "unit_price": 1.44, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LIPIDNORM 10 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "OCTOBER PHARMA", "price_egp": 14.4, "pack_count": 10, "unit_price": 1.44, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZETAMIBE 10 MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 34.8, "pack_count": 10, "unit_price": 3.48, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZETLIP 10MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIORIGINAL INTERNATIONAL GROUP PHARMA EGYPT", "price_egp": 35.0, "pack_count": 10, "unit_price": 3.5, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CHOLETIMB 10 MG 14 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI)", "price_egp": 65.0, "pack_count": 14, "unit_price": 4.64, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "EZETROL 10MG 7 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MERCK SHARP & DOHME > GLOBAL NAPI PHARMACEUTICALS", "price_egp": 90.0, "pack_count": 7, "unit_price": 12.86, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "dyslipidemia" }, { "id": 647, "generic": "Fenofibrate", "line": 3, "is_adjunct": false, "form": "oral.solid", "strength_mg": 160.0, "adult_dose": "160 mg once daily with meals for severe hypertriglyceridemia", "adult_duration": "long-term", "dose_source": "Egyptian National Drug Formulary - Cardiovascular 2024 (fenofibrate monograph)", "rationale": "Fibrate that activates PPAR-alpha to lower triglycerides, used for severe hypertriglyceridemia that is not adequately addressed by a statin, since statins primarily target LDL rather than triglycerides.", "cautions": [ "Monitor renal function and LFTs.", "Fenofibrate dosing depends on the formulation - the formulary gives 200 mg for the capsule and directs you to the product leaflet. The 160 mg here is the tablet strength.", "There is a risk of cholelithiasis and gallbladder disease.", "There is an increased risk of myopathy when combined with statins." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Not recommended in children", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "LIPANTHYL SUPRA 160MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM > ABBOTT LABORATORIES", "price_egp": 141.0, "pack_count": 30, "unit_price": 4.7, "strength_mg": 160.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "dyslipidemia" } ] }