# Simple corneal abrasion

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: Egyptian National Drug Formulary - Antimicrobial 2023 · AAO Corneal Abrasion Guidelines · Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353) · No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as comfort needs · Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc) · Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-abrasion-full.txt) · Domingo E, Moshirfar M, Zeppieri M, et al. Corneal Abrasion. [Updated 2024 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID NBK532960.
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary - Antimicrobial 2023
- Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353)
- No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as comfort needs
- Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc)
- Corneal Abrasion - StatPearls (NBK532960), Treatment / Management
- Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-abrasion-full.txt)
- Domingo E, Moshirfar M, Zeppieri M, et al. Corneal Abrasion. [Updated 2024 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID NBK532960.

## Treatment metadata

- Tobramycin — eye
- Ofloxacin — eye
- Erythromycin — eye
- Sodium hyaluronate — eye

## Complete treatment card

```text
SIMPLE CORNEAL ABRASION
Sources: Egyptian National Drug Formulary - Antimicrobial 2023 · AAO Corneal Abrasion Guidelines ·
         Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353) · No labelled dose - a
         lubricant appliance, not a licensed medicine; instilled as often as comfort needs ·
         Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc) ·
         Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article (corneal-
         abrasion-full.txt) · Domingo E, Moshirfar M, Zeppieri M, et al. Corneal Abrasion. [Updated
         2024 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026
         Jan-. Bookshelf ID NBK532960.
Review status: REVIEWED against 6 sources listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (6)
    - Trouble getting the eye open, dislike of light and a gritty feeling with pain all point to
      injury of the cornea  [photophobia]
    - Redness, sensitivity to light, streaming tears and blurred vision go with it  [blurred vision
      · photophobia · redness]
    - Marked screwing up of the eye is part of the picture
    - Small fragments from woodwork or metalwork can lodge under the lid and graze the cornea
    - Usual causes are a poke from a finger or nail, make-up, branches, grit, contact lenses,
      splashed chemicals, hard rubbing, radiation burns and ingrowing lashes
    - Injuries to the eye frequently go unmentioned unless you ask
  SIGNS - what you find (8)
    - The dye pools in the break and glows green under a cobalt blue lamp
    - Look for a red bulbar conjunctiva, slight corneal swelling, engorged ciliary vessels and a
      small pupil  [small pupil]
    - A pupil that is not properly round raises the possibility of a ruptured globe
    - A hazy cornea means oedema from hard rubbing or damage to epithelium and stroma  [corneal
      changes · oedema]
    - An opacity or an infiltrate in the cornea suggests an ulcer or infection instead
    - Blood or pus settled in the front chamber calls for immediate referral to an ophthalmologist
      [pus]
    - A graze over the middle of the cornea drops the acuity, and a marked drop warrants specialist
      referral
    - Note any abnormality of eye movement
  TESTS (8)
    - Staining with fluorescein is the single most useful bedside test
    - Put anaesthetic in the eye or on the strip, touch it to the conjunctiva; the dye runs off
      intact cornea and lodges in any break
    - If pain prevents the patient sitting at the slit lamp, begin with a torch
    - Topical anaesthetic makes the examination possible
    - Injury leaves a line-shaped or map-shaped stain
    - In a lens wearer, scattered pinpoint marks run together into a rounded defect in the middle
    - A branching pattern of uptake means herpes keratitis and needs treating at once
    - Upright scratch lines mean something is sitting under the lid, so turn the lids back and look
  IF NOT THIS - what else fits (8)
    - Keratoconjunctivitis
    - Dry eye syndrome
    - Angle-closure glaucoma of sudden onset
    - Uveitis, or keratitis from bacteria, fungus or herpes
    - Ulcer of the cornea
    - Recurrent erosion syndrome
    - Neurotrophic exposure keratopathy, or a complication of previous surgery
    - Ingrowing lashes, and keratitis from ultraviolet light or chemicals
  Source  StatPearls "Corneal Abrasion" - disease-level clinical article
  Status  traced to the source above

Rx: Prophylaxis  |  Contact lens wearer - Pseudomonas cover  |  Prophylaxis - not obtainable in
    Egypt  |  Main treatment

PROPHYLAXIS
1. TOBRAMYCIN                                             [1st line]
   Adult    Instill 1-2 drops into affected eye(s) every 4 hours
   Peds     3 months and over: 1 to 2 drops into affected eye every 4 hours.
            (Children >2 months: Instill 1-2 drops into affected eye(s) every 4 hours)
   Source   Tobramycin 0.3% eye drops SmPC (https://www.medicines.org.uk/emc/product/3120/smpc)
   Why      Prophylactic topical antibiotic to prevent bacterial keratitis while epithelium heals
   Caution  CONTACT LENS WEARERS REQUIRE PSEUDOMONAS COVER (e.g. ofloxacin or levofloxacin) and MUST
            NOT wear lenses until 24 hours after full epithelial closure.
            NEVER prescribe topical anesthetic drops (tetracaine/benoxinate) for outpatient home use
            (causes rapid corneal melting and permanent blindness).
            Do NOT patch the eye if contact-lens-related or organic/plant material injury (high
            infection risk).
            RED FLAG - Topical corticosteroid drops must never be used on a corneal abrasion - they
            delay healing and increase the risk of infection.
            An irregularly shaped pupil after eye trauma suggests globe rupture and needs immediate
            ophthalmology involvement.
            RED FLAG - Aminoglycoside eye drops should be avoided in patients who do not wear
            contact lenses.
            Evert both eyelids before concluding the examination - a retained subtarsal foreign body
            typically produces vertical linear corneal scratches.
            Branching, dendritic fluorescein staining is herpes keratitis rather than a simple
            abrasion and needs immediate treatment.
            RED FLAG - Do not patch an uncomplicated minor traumatic or foreign-body corneal
            abrasion.
            Inspect the anterior chamber for blood in it (hyphema) at the first examination.
            Any significant reduction in visual acuity requires referral to an ophthalmologist.
            RED FLAG - Purulent discharge, or a drop in vision of more than one to two Snellen
            lines, is an indication for urgent ophthalmology referral.
            RED FLAG - A child who is still unwilling to open the injured eye 24 hours later needs
            urgent ophthalmology referral.
   Egypt    SWIXTOBRAM 0.3% EYE DROPS 5 ML   CHEMIPHARM           6.50 EGP
            T GRAND 0.3% EYE DROPS 5 ML      DELTA GRAND P...     7.00 EGP
            TOBRAL 0.3% EYE DROPS 5 ML       KAHIRA               7.00 EGP
            TOBRACTIVA 0.3% EYE DROPS 5 ML   EPCI                18.00 EGP
            AVAZIR 0.3% EYE DROPS 10 ML      ORCHIDIA PHAR...    28.00 EGP
            TOBREX 0.3% EYE DROPS 5 ML       NOVARTIS > NO...    32.50 EGP
            TOBRIN 0.3% EYE.OINT. 5 GM       EIPICO              23.00 EGP
            AVAZIR 0.3% EYE OINT. 5 GM       ORCHIDIA PHAR...    26.00 EGP


CONTACT LENS WEARER - PSEUDOMONAS COVER
2. OFLOXACIN                                              [1st line]
   Adult    1-2 drops into the affected eye every 2-4 hours for the first 2 days, then 4 times
            daily. Never longer than 10 days. x 5-7 days, maximum 10
   Peds     For all ages (1 year and older): one to two drops in the affected eye(s) every two to
            four hours for the first two days and then four times daily. Safety and effectiveness in
            infants below the age of one year have not been established.
   Source   Exocin 3 mg/ml Eye Drops SmPC section 4.2 (eMC product 1353)
   Why      For a contact lens wearer, where the organism to fear is Pseudomonas. Drops cost 6 EGP,
            so there is no reason to compromise on cover.
   Caution  The label warns of corneal perforation when a fluoroquinolone drop is used on an eye
            with an epithelial defect - which is what an abrasion is. Review the eye, and refer if
            it is not healing.
            A contact lens wearer with an abrasion does not go back into lenses until the eye is
            healed and reviewed.
            Refer same day for any white infiltrate, hypopyon, or vision that is getting worse -
            that is keratitis, not an abrasion.
            Recommended that EXOCIN not be used in pregnant women.
   Egypt    QUIFLURO 0.3% EYE DROPS 5 ML     PHAROPHARMA          6.00 EGP
            OFLOXIN 0.3% EYE DROPS 5 ML      KAHIRA               7.00 EGP
            OFLOXACIN 0.3% EYE DROPS 10 ML   SIGMA TEC            7.50 EGP
            OFLICIN 0.3% EYE DROPS 5 ML      MEMPHIS              8.00 EGP
            OFLOSWIX 0.3% EYE DROPS 5 ML     CHEMIPHARM          12.00 EGP
            OCUFLOX 0.3% EYE DROPS 5 ML      ALEXANDRIA          19.50 EGP
            OPTIFLOX 0.3% EYE DROPS 5 ML     JAMJOOM PHARM...    19.50 EGP
            OFLOX 0.3% EYE DROPS 5 ML        ALLERGAN > SO...    20.40 EGP


PROPHYLAXIS - NOT OBTAINABLE IN EGYPT
3. ERYTHROMYCIN                                           [1st line]
   Adult    Erythromycin ointment, 4 times a day across the 5 days, for a patient who does not wear
            contact lenses. x 5 days
   Peds     30-50 mg/kg/day  [child max 2000 mg]
            (General dosing, susceptible infection: Infants, Children, and
            Adolescents: Oral: Base, ethylsuccinate, stearate: 30 to 50
            mg/kg/day divided every 6 to 8 hours usually; for severe infection
            may double dose; maximum daily dose: Mild to moderate infection:
            2,000 mg/day; severe infection: 4,000 mg/day.)
            3kg -> 90-150 mg/day                     4kg -> 120-200 mg/day
            5kg -> 150-250 mg/day                    6kg -> 180-300 mg/day
            7kg -> 210-350 mg/day                    8kg -> 240-400 mg/day
            9kg -> 270-450 mg/day                    10kg -> 300-500 mg/day
            11kg -> 330-550 mg/day                   12kg -> 360-600 mg/day
            13kg -> 390-650 mg/day                   14kg -> 420-700 mg/day
            15kg -> 450-750 mg/day                   16kg -> 480-800 mg/day
            17kg -> 510-850 mg/day                   18kg -> 540-900 mg/day
            19kg -> 570-950 mg/day                   20kg -> 600-1000 mg/day
            21kg -> 630-1050 mg/day                  22kg -> 660-1100 mg/day
            23kg -> 690-1150 mg/day                  24kg -> 720-1200 mg/day
            25kg -> 750-1250 mg/day                  26kg -> 780-1300 mg/day
            27kg -> 810-1350 mg/day                  28kg -> 840-1400 mg/day
            29kg -> 870-1450 mg/day                  30kg -> 900-1500 mg/day
            31kg -> 930-1550 mg/day                  32kg -> 960-1600 mg/day
            33kg -> 990-1650 mg/day                  34kg -> 1020-1700 mg/day
            35kg -> 1050-1750 mg/day                 36kg -> 1080-1800 mg/day
            37kg -> 1110-1850 mg/day                 38kg -> 1140-1900 mg/day
            39kg -> 1170-1950 mg/day                 40kg -> 1200-2000 mg/day
            41kg -> 1230-2000 mg/day (upper capped)  42kg -> 1260-2000 mg/day (upper capped)
            43kg -> 1290-2000 mg/day (upper capped)  44kg -> 1320-2000 mg/day (upper capped)
            45kg -> 1350-2000 mg/day (upper capped)  46kg -> 1380-2000 mg/day (upper capped)
            47kg -> 1410-2000 mg/day (upper capped)  48kg -> 1440-2000 mg/day (upper capped)
            49kg -> 1470-2000 mg/day (upper capped)  50kg -> 1500-2000 mg/day (upper capped)
   Source   Corneal Abrasion - StatPearls - NCBI Bookshelf - disease-level clinical article
            (corneal-abrasion-full.txt) for the topical ointment regimen; the systemic paediatric
            figures are from Egyptian National Drug Formulary - Antimicrobial 2023 (erythromycin
            monograph), Dosing: Pediatric, general dosing: "Oral: Base, ethylsuccinate, stearate: 30
            to 50 mg/kg/day divided every 6 to 8 hours usually; for severe infection may double
            dose; maximum daily dose: Mild to moderate infection: 2,000 mg/day; severe infection:
            4,000 mg/day".
   Why      Topical antibiotic ointment providing antibiotic cover and ocular lubrication for simple
            corneal abrasion in non-contact lens wearers.
   Caution  Erythromycin is not obtainable in Egypt in this form. Every erythromycin eye product is
            absent from the national product list entirely, all 16 oral products are marked
            withdrawn, and the only three live topical products are acne preparations. Prescribe
            tobramycin or ofloxacin eye drops instead - both are stocked and cover the same job,
            tobramycin for a patient who does not wear lenses, ofloxacin for one who does.
            For non-contact lens wearers only; contact lens wearers require anti-pseudomonal
            coverage (e.g. fluoroquinolone or aminoglycoside).
            Re-evaluate if symptoms persist beyond 3 days.
   Egypt    AKNEMYCIN 2% OINT. 15 GM         MUP > HERMAL-...     5.00 EGP
                -> ? different route - not eye, discontinued
            ACNI-CARE 2% TOP. GEL. 20 GM     SIGMA                6.50 EGP
                -> ? different route - not eye, discontinued
            ERYTHROCID 200 MG/5ML SUSP. 60ML CID                  5.60 EGP
                -> ? different route - not eye, discontinued
            ERYTHROMYCIN PHARCO 200MG/5ML SUSP. 60ML PHARCO                                 7.50 EGP
                -> ? different route - not eye, discontinued
            AKNEMYCIN 2% SOLUTION 25 ML      MUP > HERMAL-...     9.00 EGP
                -> ? different route - not eye, discontinued
            ETHYRONATE 200MG/5ML SUSP. 100 ML UNIPHARMA CO. > UNIPHARMA                     9.50 EGP
                -> ? different route - not eye, discontinued
            ETHYRONATE 400MG/5ML SUSP. 100 ML UNIPHARMA CO. > UNIPHARMA                    11.75 EGP
                -> ? different route - not eye, discontinued
            ACNI-CARE 2% LOTION 25 ML        SIGMA               20.00 EGP
                -> ? different route - not eye, discontinued


MAIN TREATMENT - give alongside
4. SODIUM HYALURONATE                                     [add-on - not a substitute]
   Adult    Instill preservative-free lubricating drops 1-2 drops every 2-4 hours as needed for
            comfort x 3-5 days
   Peds     Preservative-free lubricating drops as needed
   Source   No labelled dose - a lubricant appliance, not a licensed medicine; instilled as often as
            comfort needs
   Why      Promotes epithelial re-surfacing and reduces eyelid friction
   Caution  Re-evaluate within 24-48 hours if pain worsens, photophobia increases, or vision
            degrades.
            Sodium hyaluronate drops are sold as an appliance rather than a licensed medicine, so no
            regulator has set a dose for them. Use them as often as the eye needs and judge by
            comfort.
   Egypt    LUBRIVISC 0.1% EYE DROPS 10 ML   RAMEDA > HIKM...    32.00 EGP
            HYALUGRAND 0.2% EYE DROPS 10 ML  DELTA GRAND P...    41.00 EGP
            HYALOPTIC 0.2% EYE DROPS 10 ML   PHARCO              48.00 EGP
            HYFRESH 0.2% EYE DROPS 10 ML     JAMJOOM PHARM...    75.00 EGP
            XILOIAL MONO EYE DROPS 20 RE-CLOSABLE VIALS * 0.5 ML FARMIGEA > HABIB SC...   265.00 EGP
            VISMED MULTI 0.18% EYE DROPS 10 ML TRB CHEMEDICA SA > RHEUMA                  335.00 EGP
            VISMED 0.3% EYE GEL 20 X 0.45 ML SDU TRB CHEMEDICA SA > RHEUMA                390.00 EGP
            VISMED MULTI 0.3% EYE GEL 10 ML  TRB CHEMEDICA...   390.00 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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