# Concussion

- Category: acute
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: MSF Essential Drugs 2024 - paracetamol (oral)
- Verified date: 2026-08

## Verified against

- MSF Essential Drugs 2024 - paracetamol (oral)
- Concussion - disease-level clinical article (concussion-clinical.txt)

## Treatment metadata

- Paracetamol — 500 mg — oral.solid
- Referral & safety-netting (no drug therapy)

## Complete treatment card

```text
CONCUSSION
Sources: MSF Essential Drugs 2024 - paracetamol (oral)
Review status: REVIEWED against MSF Essential Drugs 2024 - paracetamol (oral), Concussion - disease-
               level clinical article (concussion-clinical.txt)  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (6)
    - Cognitive symptoms include confusion, disorientation, amnesia, mental fogginess, and trouble
      concentrating  [confusion · memory loss · poor concentration]
    - Physical symptoms include headache, dizziness, balance problems, and visual changes
      [dizziness · headache · unsteadiness]
    - Sleep-related complaints include drowsiness and either more or less sleep than usual, or
      trouble falling asleep  [drowsiness]
    - Over 90% of patients diagnosed with concussion never lose consciousness, though a loss of
      consciousness signals a potentially more serious injury  [loss of consciousness]
    - Symptoms do not always start right after the injury and can appear hours to days later
    - A history of more numerous, severe, or longer-lasting prior concussions predicts a longer
      recovery from this one
  SIGNS - what you find (3)
    - Exam should closely check the head and neck for any structural injury
    - A full neurologic exam covers strength, sensation, reflexes, eye movements including saccades
      and nystagmus, and balance testing  [nystagmus]
    - Cognitive testing should formally assess orientation and higher-level thinking
  TESTS (6)
    - Concussion remains a clinical diagnosis; there is no single defining finding or minimum
      symptom count required
    - The SCAT6 tool helps assess athletes on the sideline after a possible head injury, with a
      child version for ages 5 to 12
    - Severe headache, seizures, focal deficits, loss of consciousness, or worsening mental status
      should prompt an emergency evaluation for a more serious injury
    - A normal head CT scan does not rule out a concussion
    - PECARN criteria and the Canadian Head CT Rule are decision tools used to decide whether
      imaging is needed
    - MRI can be considered when concussion symptoms persist beyond 7 days
  IF NOT THIS - what else fits (2)
    - Right after the injury, more severe alternatives such as a cervical spine injury, brain bleed,
      or skull fracture must be considered
    - Persisting symptoms can overlap with pre-existing headache disorders, anxiety, depression,
      PTSD, ADHD, or sleep problems, complicating the diagnosis
  Score   Glasgow Coma Scale - How depressed is this level of consciousness?
  Source  StatPearls "Concussion" - disease-level clinical article
  Status  traced to the source above

1. PARACETAMOL                                            [1st line]
   Adult    1 g three or four times daily, maximum 4 g in 24 hours - As needed for pain or fever
   Peds     15 mg/kg/dose  [child max 500 mg]
            (Child 1 month and over: 15 mg/kg per dose, 3 or 4 times daily,
            maximum 60 mg/kg daily. Child under 1 month: 10 mg/kg per dose, 3
            or 4 times daily, maximum 40 mg/kg daily. MSF's own weight table
            gives one 500 mg tablet three times daily from 30 kg to under 50
            kg, so 500 mg is the per-dose ceiling; the 60 mg/kg daily total
            still applies.)
            3kg -> 45 mg/dose                 4kg -> 60 mg/dose
            5kg -> 75 mg/dose                 6kg -> 90 mg/dose
            7kg -> 105 mg/dose                8kg -> 120 mg/dose
            9kg -> 135 mg/dose                10kg -> 150 mg/dose
            11kg -> 165 mg/dose               12kg -> 180 mg/dose
            13kg -> 195 mg/dose               14kg -> 210 mg/dose
            15kg -> 225 mg/dose               16kg -> 240 mg/dose
            17kg -> 255 mg/dose               18kg -> 270 mg/dose
            19kg -> 285 mg/dose               20kg -> 300 mg/dose
            21kg -> 315 mg/dose               22kg -> 330 mg/dose
            23kg -> 345 mg/dose               24kg -> 360 mg/dose
            25kg -> 375 mg/dose               26kg -> 390 mg/dose
            27kg -> 405 mg/dose               28kg -> 420 mg/dose
            29kg -> 435 mg/dose               30kg -> 450 mg/dose
            31kg -> 465 mg/dose               32kg -> 480 mg/dose
            33kg -> 495 mg/dose               34kg -> 500 mg/dose (capped)
            35kg -> 500 mg/dose (capped)      36kg -> 500 mg/dose (capped)
            37kg -> 500 mg/dose (capped)      38kg -> 500 mg/dose (capped)
            39kg -> 500 mg/dose (capped)      40kg -> 500 mg/dose (capped)
            41kg -> 500 mg/dose (capped)      42kg -> 500 mg/dose (capped)
            43kg -> 500 mg/dose (capped)      44kg -> 500 mg/dose (capped)
            45kg -> 500 mg/dose (capped)      46kg -> 500 mg/dose (capped)
            47kg -> 500 mg/dose (capped)      48kg -> 500 mg/dose (capped)
            49kg -> 500 mg/dose (capped)      50kg -> 500 mg/dose (capped)
   Source   MSF Essential Drugs 2024 - paracetamol (oral)
   Why      Symptomatic relief of the pain and fever only. It does not treat the cause, and the dose
            is the same whatever the cause is.
   Caution  Relief only - it does not treat what is causing the pain or fever.
            Check every other product the patient is taking for paracetamol; combination cold and
            flu preparations are the usual route to an accidental overdose.
            Reduce the dose in significant liver disease, chronic alcohol use, or low body weight.
            RED FLAG - Worsening headache or repeated vomiting, increasing drowsiness or difficulty
            rousing the patient, a seizure after the injury, unequal pupils or new focal weakness,
            or clear fluid leaking from the nose or ear (possible skull fracture): refer for
            emergency assessment.
   Egypt    FEBRIMOL 500 MG 20 TAB.          PHARCO               3.50 EGP (0.17/unit)
            CETAMOL 500 MG 20 TABS.          MEMPHIS              8.00 EGP (0.40/unit)
            PARACETAMOL-MUP 500MG B.P. 20 TABS. MUP                            13.00 EGP (0.65/unit)
            CETAL 500 MG 20 TABS.            EIPICO              24.00 EGP (1.20/unit)
            ARKADOLOW 500 MG 30 F.C. TABS.   UTOPIA              42.00 EGP (1.40/unit)
            PARAMOL 500MG 20 TAB.            MISR                38.00 EGP (1.90/unit)
            ADOL 500MG 24 CAPLETS            JULPHAR             32.00 EGP
            AUGICETAMIDE 500 MG 20 SACHETS   AUG PHARMA          50.00 EGP
            FEBRIMOL ORAL DROPS 20 ML        PHARCO               4.00 EGP
                -> ? strength differs, ? different route - not oral solid
            THERA-LO 3.2G/100ML ORAL SUSP. 100 ML PHAROPHARMA                               5.00 EGP
                -> ? strength differs, ? different route - not oral solid

2. REFERRAL & SAFETY-NETTING (NO DRUG THERAPY)            [1st line]
   Adult    
   Source   Concussion - disease-level clinical article (concussion-clinical.txt)
   Why      Carries the referral criteria and warning signs for this condition, which apply
            whichever treatment is chosen.
   Caution  RED FLAG - Send to the emergency department, as a severe head injury: a seizure,
            headache that is severe, any focal neurological deficit, consciousness lost, mental
            state declining, or symptoms that keep getting worse.

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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