{ "schema_version": 1, "kind": "condition", "id": "bacterial-folliculitis", "name": "Bacterial Folliculitis", "category": "acute", "sources": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361) · Winters RD, Mitchell M. Folliculitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Bookshelf ID: NBK547754. PMID: 31613534. · Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 · Egyptian National Drug Formulary - Antimicrobial 2023, mupirocin monograph · Egyptian National Drug Formulary - Antimicrobial 2023, cephalexin monograph · Egyptian National Drug Formulary - Antimicrobial 2023 (sulfamethoxazole and trimethoprim monograph)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361) · Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 · Egyptian National Drug Formulary - Antimicrobial 2023, mupirocin monograph · Egyptian National Drug Formulary - Antimicrobial 2023, cephalexin monograph", "verified_date": "2026-08", "treatments": [ { "id": 238, "generic": "Mupirocin", "line": 1, "is_adjunct": false, "form": "topical", "strength_mg": null, "adult_dose": "Apply 2% ointment to the affected area three times daily", "adult_duration": "7 to 14 days, with review at 3 to 5 days if there is no response", "dose_source": "Egyptian Drug Authority - National Guidance of Rational Antimicrobial Use in the Management of Skin and Soft Tissue Infection, EDREX:GU.CAP.Care.015 version 1, 11/2025 for the indication - verbatim, the folliculitis row of its treatment table: \"Folliculitis: Topical antibiotics (e.g., mupirocin, retapamulin).\" Dose from the same document's dosing appendix - verbatim: \"Mupirocin: 2% ointment applied 3 times per day.\" Duration from Egyptian National Drug Formulary - Antimicrobial 2023, mupirocin monograph - verbatim: \"Apply to affected area 2 to 3 times daily, typically for 7 to 14 days depending on severity and clinical response; if no response after 3 to 5 days, re-evaluate treatment.\"", "rationale": "The treatment Egypt's own national guidance gives for folliculitis, and the one the international article names first for disease extensive enough to treat at all. Most simple staphylococcal folliculitis settles on its own within a few days.", "cautions": [ "Most simple folliculitis needs no antibiotic. The source expects a few pustules to resolve spontaneously within a few days, and reserves topical treatment for more extensive disease.", "A painful nodule with a central pustule is a boil, not folliculitis, and a coalesced mass draining from several follicles is a carbuncle. Both are drainage decisions before they are antibiotic ones.", "Re-evaluate rather than extend if there is no response after 3 to 5 days." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "A small amount three times daily for 5 to 10 days, with review at 5 days if there is no clinical response (Egyptian National Drug Formulary, mupirocin monograph). A topical dose is not weight-based.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "BACTROFORM 2% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "WESTERN PHARMACEUTICALS INDUSTRIES > WESTERN PHARMA", "price_egp": 35.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 15 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA", "price_egp": 35.0, "pack_count": null, "unit_price": null, "strength_mg": 15000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIRAX 2% OINT. 10 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 48.0, "pack_count": null, "unit_price": null, "strength_mg": 10000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIROCIN SAJA 2% TOP. OINT. 20 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "BIOPHARM EGYPT > SAJA PHARMA", "price_egp": 83.0, "pack_count": null, "unit_price": null, "strength_mg": 20000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MUPIRAX 2% OINT. 30 GM", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS", "price_egp": 118.0, "pack_count": null, "unit_price": null, "strength_mg": 30000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "bacterial-folliculitis" }, { "id": 237, "generic": "Flucloxacillin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": null, "adult_dose": "250 mg orally (or by intramuscular injection) four times daily; the dose may be doubled for a severe infection.", "adult_duration": "As directed (formulary gives no fixed course length for this dose; a short course, e.g. 5-7 days, is typical clinical practice for more extensive or recurrent disease).", "dose_source": "Egyptian National Drug Formulary - antimicrobial-2023.pdf, Flucloxacillin monograph (chapter PDF p361)", "rationale": "Bacterial folliculitis is usually a staphylococcal skin/soft-tissue infection, matching flucloxacillin's formulary indication; an oral course is used for more extensive or recurrent disease beyond what a topical antibiotic would cover.", "cautions": [ "No plain flucloxacillin is sold in Egypt. All 33 live products are combinations with amoxicillin or ampicillin, so the patient goes home with a second antibiotic as well - check the pack and account for it.", "Penicillin allergy is a contraindication - ask about prior reactions before prescribing.", "Spreading redness, fever, or a large fluctuant area suggests an abscess or cellulitis needing drainage or reassessment rather than oral antibiotics alone.", "Recurrent folliculitis in a diabetic or immunosuppressed patient needs closer follow-up and consideration of predisposing factors.", "Rare but serious cholestatic jaundice/hepatitis can occur, more often with longer courses and in older patients." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Age-banded rather than weight-based by mouth: 1 month to 1 year 62.5 to 125 mg, 2 to 9 years 125 to 250 mg, 10 years and older 250 to 500 mg, all four times daily (Egyptian National Drug Formulary, flucloxacillin monograph, quoting BNFC for beta-lactamase-producing staphylococcal infection including impetigo and cellulitis). Cefalexin carries a weight-based dose if one is preferred.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": null, "brands": [ { "trade_name": "FLUMOCIN 250MG 12CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 6.2, "pack_count": 12, "unit_price": 0.52, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "AMOFLUX 125/125MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > DELTA PHARMA", "price_egp": 8.25, "pack_count": 12, "unit_price": 0.69, "strength_mg": 125.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "FLUCAMOX 250MG 12CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 8.25, "pack_count": 12, "unit_price": 0.69, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "FLUMOCIN 500MG 8 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UP PHARMA", "price_egp": 6.0, "pack_count": 8, "unit_price": 0.75, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "CURAFLUX 125/125 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > PIONEER", "price_egp": 12.5, "pack_count": 12, "unit_price": 1.04, "strength_mg": 125.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "AMOFLUX 250/250MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "RAMEDA > PIONEER", "price_egp": 18.0, "pack_count": 16, "unit_price": 1.12, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "HI-FLUCIL 250/250MG 16 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 20.0, "pack_count": 16, "unit_price": 1.25, "strength_mg": 250.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "amoxicillin" }, { "trade_name": "AMPIFLUX 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 16.0, "pack_count": 12, "unit_price": 1.33, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": "ampicillin" } ], "condition_id": "bacterial-folliculitis" }, { "id": 239, "generic": "Cefalexin", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 500.0, "adult_dose": "500 mg orally every 6 hours", "adult_duration": "The formulary states no course length for skin infection - review at 5 to 7 days rather than repeating a prescription", "dose_source": "Folliculitis - StatPearls - NCBI Bookshelf (NBK547754) - disease-level clinical article (bacterial-folliculitis-full.txt) for the indication - verbatim: \"Should these prove ineffective or should the patient present with deeper folliculitis such as furunculosis and carbunculosis or more extensive involvement of the skin, then oral antibiotics such as cephalexin and dicloxacillin are options.\" The article gives no dose. Dose from Egyptian National Drug Formulary - Antimicrobial 2023, cephalexin monograph - verbatim indication \"Skin and skin structure infections: Treatment of skin and skin structure infections caused by S. aureus and/or S. pyogenes\", and dosing: \"Usual adult dosage range: Oral: 250 to 1,000 mg every 6 hours or 500 mg every 12 hours (maximum: 4 g/day)\".", "rationale": "The oral step when a topical antibiotic is not enough or the infection has gone deeper. It is the source's first-named oral option and the one obtainable as a single medicine in Egypt.", "cautions": [ "Four times a day. A missed dose matters more on a 6-hourly antibiotic than on a twice-daily one - say so when handing it over.", "Avoid after a severe or immediate reaction to a penicillin.", "Tablets and oral suspension are not bioequivalent and must not be swapped milligram for milligram - Egyptian National Drug Formulary, cephalexin monograph.", "Spreading redness, fever, or a fluctuant swelling is cellulitis or an abscess, and needs reassessment or drainage rather than a longer oral course." ], "peds_mgkg_low": 25.0, "peds_mgkg_high": 50.0, "peds_max_mg": 2000.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "25 to 50 mg/kg/day divided every 6 or 12 hours, maximum 2,000 mg/day (Egyptian National Drug Formulary, cephalexin monograph, general dosing for mild to moderate infection).", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 250, "high_mg": 500, "capped": false }, { "weight_kg": 20, "low_mg": 500, "high_mg": 1000, "capped": false }, { "weight_kg": 30, "low_mg": 750, "high_mg": 1500, "capped": false }, { "weight_kg": 40, "low_mg": 1000, "high_mg": 2000, "capped": false } ], "brands": [ { "trade_name": "CEFLODIX 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CAPS > PHAROPHARMA", "price_egp": 9.0, "pack_count": 12, "unit_price": 0.75, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEPHALEXCID 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 10.3, "pack_count": 12, "unit_price": 0.86, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEPHOXIN 500MG 12 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO B", "price_egp": 10.5, "pack_count": 12, "unit_price": 0.88, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEPHALEXIN 500MG 10 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 10.1, "pack_count": 10, "unit_price": 1.01, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MEDICEFLEXIN 500 MG 20 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "T3A PHARMA > RIVA PHARMA S.A.E.", "price_egp": 25.25, "pack_count": 20, "unit_price": 1.26, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEPHALEXIN 500MG 12 CAPS B.P.2007", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SHIFA MEDICAL PRODUCTS > OCTOBER PHARMA", "price_egp": 27.0, "pack_count": 12, "unit_price": 2.25, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "KEFLEX 500 MG 12 CAPS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HIKMA PHARMA", "price_egp": 58.0, "pack_count": 12, "unit_price": 4.83, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CEPOREX 500MG 12 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 69.0, "pack_count": 12, "unit_price": 5.75, "strength_mg": 500.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "AMTHROST 125MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > SABAA", "price_egp": 4.0, "pack_count": null, "unit_price": null, "strength_mg": 125.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "AMTHROST 250MG/5ML SUSP. 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > SABAA", "price_egp": 4.5, "pack_count": null, "unit_price": null, "strength_mg": 250.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "bacterial-folliculitis" }, { "id": 240, "generic": "Sulphamethoxazole + Trimethoprim", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": null, "adult_dose": "1 to 2 double-strength tablets every 12 to 24 hours", "adult_duration": null, "dose_source": "Egyptian National Drug Formulary - Antimicrobial 2023 (sulfamethoxazole and trimethoprim monograph) - verbatim: \"General dosing guidelines: Oral: 1 to 2 double-strength tablets every 12 to 24 hours.\"", "rationale": "Gram-negative folliculitis, the form that follows a long course of antibiotics for acne, does not respond to the anti-staphylococcal agents listed above. Co-trimoxazole is the article's first-line oral choice for it and is cheap and everywhere in Egypt.", "cautions": [ "Do not use it in sulfonamide or trimethoprim allergy, in megaloblastic anaemia from folate deficiency, in marked liver damage, in severe kidney disease that cannot be monitored, or in an infant under 2 months.", "For gram-negative folliculitis, the kind that follows prolonged antibiotic treatment - not for ordinary staphylococcal folliculitis, which mupirocin, flucloxacillin and cefalexin already cover.", "The formulary does not list skin infection among co-trimoxazole's indications; the indication here rests on the disease article." ], "peds_mgkg_low": 6.0, "peds_mgkg_high": 12.0, "peds_max_mg": 320.0, "peds_basis": "day", "peds_unit": "mg", "peds_note": "From 2 months of age: 6 to 12 mg/kg a day of the trimethoprim component, split every 12 hours, up to 160 mg of trimethoprim per dose. Not for infants under 2 months.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": null, "peds_doses": [ { "weight_kg": 10, "low_mg": 60, "high_mg": 120, "capped": false }, { "weight_kg": 20, "low_mg": 120, "high_mg": 240, "capped": false }, { "weight_kg": 30, "low_mg": 180, "high_mg": 320, "capped": true }, { "weight_kg": 40, "low_mg": 240, "high_mg": 320, "capped": true } ], "brands": [ { "trade_name": "CO-TRIMOXAZOLE 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 5.0, "pack_count": 20, "unit_price": 0.25, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "COTRIL 400/80MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NASR", "price_egp": 38.0, "pack_count": 20, "unit_price": 1.9, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTAZOLE FORTE 800/160MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 56.0, "pack_count": 20, "unit_price": 2.8, "strength_mg": 160.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTRIN D.S 10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE > ASPEN PHARMA TRADING LIMITED", "price_egp": 28.0, "pack_count": 10, "unit_price": 2.8, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEPTAZOLE 400/80MG 20*10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 340.0, "pack_count": 10, "unit_price": 34.0, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SUTRIM 400/80MG 20*10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 340.0, "pack_count": 10, "unit_price": 34.0, "strength_mg": 80.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CO-TRIMOXAZOLE 200/40MG SUSP. 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 6.0, "pack_count": null, "unit_price": null, "strength_mg": 40.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "SUTRIM 200/40MG SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 18.5, "pack_count": null, "unit_price": null, "strength_mg": 40.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "bacterial-folliculitis" } ] }