# Aphthous Stomatitis (Recurrent mouth ulcers)

- Category: chronic
- Review status: reviewed (every claim checked against a document named on this page)
- Sources: British Association of Oral Surgeons Guidelines 2019 · Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529) · Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste (printed p. 177)
- Verified date: 2026-08

## Verified against

- Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste (printed p. 177)
- Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529)

## Treatment metadata

- Triamcinolone — oromucosal.paste
- Chlorhexidine — topical

## Complete treatment card

```text
APHTHOUS STOMATITIS (RECURRENT MOUTH ULCERS)
Sources: British Association of Oral Surgeons Guidelines 2019 · Corsodyl 0.2% Mouthwash SmPC
         sections 4.2 and 4.4 (eMC product 529) · Egyptian National Drug Formulary, endocrine 2024,
         triamcinolone monograph, oral paste (printed p. 177)
Review status: REVIEWED against 2 sources listed above  (2026-08)

IS IT THIS? - reference only, to read alongside your own examination
  SYMPTOMS - what the patient reports (2)
    - The hallmark is recurring, painful mouth ulcers that can last from a few days up to several
      months  [mouth ulcers]
    - Oral discomfort can precede the ulcer appearing, in the minor form
  SIGNS - what you find (8)
    - Minor ulcers are small, usually under 5 mm, oval or round, 1 to 6 at a time, ringed by
      erythema, and covered by a gray-white pseudomembrane  [mouth ulcers · redness]
    - Minor ulcers mainly occur on non-keratinized mucosa - buccal, labial, floor of mouth - and
      heal within two weeks without scarring
    - Major ulcers are bigger, over 10 mm, and persist 5 to 10 weeks, usually healing with a scar
      [mouth ulcers · scarring]
    - Major ulcers can appear anywhere in the mouth, including the oropharynx
    - Major ulcers do not usually follow a cyclical pattern  [mouth ulcers]
    - Herpetiform ulcers are painful, small, and numerous, up to 100 at once, each 2 to 3 mm and
      lasting one to two weeks  [mouth ulcers]
    - Herpetiform ulcers favor the floor of the mouth and the tip and edges of the tongue
    - Herpetiform ulcers can merge into one large, irregular ulcer that heals with scarring  [mouth
      ulcers · scarring]
  TESTS (2)
    - Diagnosis is clinical, but Behcet disease, nutritional deficiency, or inflammatory bowel
      disease should be excluded, especially with sudden adult onset
    - Work-up for anemia or deficiency often checks CBC, red cell folate, ferritin, and vitamin B12,
      which can also flag GI disease
  IF NOT THIS - what else fits (4)
    - Behcet disease brings recurrent genital ulcers, skin lesions, posterior uveitis, and
      neuro/GI/renal/hematologic/joint involvement
    - MAGIC/Sweet syndrome brings sudden fever, leukocytosis, and plum-colored papules or plaques,
      with malignancy in about half of patients
    - PFAPA syndrome brings periodic fever, pharyngitis, aphthae, and cervical adenitis in young
      children; most improve with tonsillectomy
    - Cyclic neutropenia brings fever, skin abscesses, lymphadenopathy, and respiratory infections,
      plus severe gingivitis and aggressive periodontitis
  Source  StatPearls "Recurrent Aphthous Stomatitis" - disease-level clinical article
  Status  traced to the source above

1. TRIAMCINOLONE                                          [1st line]
   Adult    Coat the ulcer with a thin film of 0.1% oral paste - just enough to cover it, not rubbed
            in - two or three times a day, preferably after meals
   Peds     Children: same oral paste dose as adults; the monograph carries no age restriction for
            the oral paste.
   Source   Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste
            (printed p. 177)
   Why      Topical corticosteroid paste that damps local mucosal inflammation, easing pain and
            speeding healing of aphthous ulcers; withheld from ulcers that are actually fungal or
            viral, since suppressing local immunity there would let those infections worsen.
   Caution  Press a small dab onto ulcer without rubbing until thin film forms.
            Do not apply inside fungal or viral oral infections (e.g. herpes, thrush).
            Investigate for iron, folate, B12 deficiency or IBD if ulcers are recurrent/intractable.
   Egypt    TOPICORT 0.1% CREAM 20 GM        PHARCO               6.00 EGP
                -> ? different route - not oromucosal.paste
            PHARCOCINOLONE 40MG/ML I.M AMP.  CHEMIPHARM > ...     8.00 EGP
                -> ? different route - not oromucosal.paste
            AMCINOL 40MG/ML I.M AMP.         SIGMA TEC           11.00 EGP
                -> ? different route - not oromucosal.paste
            EPIRELEFAN 40MG/ML I.M AMP.      EIPICO              38.00 EGP
                -> ? different route - not oromucosal.paste
            SYNTHECORTIN 40MG/ML I.M AMP.    MUP                 54.00 EGP
                -> ? different route - not oromucosal.paste

2. CHLORHEXIDINE                                          [add-on - not a substitute]
   Adult    Rinse with 10 mL of 0.2% mouthwash for 1 minute twice daily - Continue for 48 hours
            after clinical resolution
   Peds     Children under 12 years of age should not use the product unless recommended by a
            healthcare professional.
   Source   Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529)
   Why      Antiseptic mouthwash added alongside the topical steroid to reduce the bacterial load
            over the ulcer and guard against secondary infection; supports the anti-inflammatory
            treatment rather than replacing it.
   Caution  Accelerates healing and prevents secondary bacterial infection of ulcers.
            May cause reversible brown staining of teeth and tongue with prolonged use.
            Do not rinse with water or use toothpaste immediately after rinsing.
            Do not use straight after toothpaste - it inactivates chlorhexidine. Separate the two,
            rinsing the mouth in between, or use them at different times of day. A course of about
            one month is what the label describes; staining of the teeth is temporary.
   Egypt    ELUGEL ORAL GEL 20 GM            GLOBAL NAPI P...     6.50 EGP
            RECARE ORAL GEL 30 GM            UNIPHARMA CO....    14.95 EGP

Prices are indicative (dataset snapshot 2026-06); verify with the pharmacy.
```

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