{
  "schema_version": 1,
  "kind": "condition",
  "id": "aphthous-stomatitis",
  "name": "Aphthous Stomatitis (Recurrent mouth ulcers)",
  "category": "chronic",
  "sources": "British Association of Oral Surgeons Guidelines 2019 · Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529) · Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste (printed p. 177)",
  "review_status": "reviewed",
  "verified_against": "Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste (printed p. 177) · Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 212,
      "generic": "Triamcinolone",
      "line": 1,
      "is_adjunct": false,
      "form": "oromucosal.paste",
      "strength_mg": null,
      "adult_dose": "Coat the ulcer with a thin film of 0.1% oral paste - just enough to cover it, not rubbed in - two or three times a day, preferably after meals",
      "adult_duration": null,
      "dose_source": "Egyptian National Drug Formulary, endocrine 2024, triamcinolone monograph, oral paste (printed p. 177)",
      "rationale": "Topical corticosteroid paste that damps local mucosal inflammation, easing pain and speeding healing of aphthous ulcers; withheld from ulcers that are actually fungal or viral, since suppressing local immunity there would let those infections worsen.",
      "cautions": [
        "Press a small dab onto ulcer without rubbing until thin film forms.",
        "Do not apply inside fungal or viral oral infections (e.g. herpes, thrush).",
        "Investigate for iron, folate, B12 deficiency or IBD if ulcers are recurrent/intractable."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children: same oral paste dose as adults; the monograph carries no age restriction for the oral paste.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "TOPICORT 0.1% CREAM 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 6.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PHARCOCINOLONE 40MG/ML I.M AMP.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "CHEMIPHARM > PHARCO B",
          "price_egp": 8.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "AMCINOL 40MG/ML I.M AMP.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "SIGMA TEC",
          "price_egp": 11.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "EPIRELEFAN 40MG/ML I.M AMP.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EIPICO",
          "price_egp": 38.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "SYNTHECORTIN 40MG/ML I.M AMP.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MUP",
          "price_egp": 54.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 40.0,
          "exact_strength": true,
          "exact_form": false,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "aphthous-stomatitis"
    },
    {
      "id": 213,
      "generic": "Chlorhexidine",
      "line": 2,
      "is_adjunct": true,
      "form": "topical",
      "strength_mg": null,
      "adult_dose": "Rinse with 10 mL of 0.2% mouthwash for 1 minute twice daily",
      "adult_duration": "Continue for 48 hours after clinical resolution",
      "dose_source": "Corsodyl 0.2% Mouthwash SmPC sections 4.2 and 4.4 (eMC product 529)",
      "rationale": "Antiseptic mouthwash added alongside the topical steroid to reduce the bacterial load over the ulcer and guard against secondary infection; supports the anti-inflammatory treatment rather than replacing it.",
      "cautions": [
        "Accelerates healing and prevents secondary bacterial infection of ulcers.",
        "May cause reversible brown staining of teeth and tongue with prolonged use.",
        "Do not rinse with water or use toothpaste immediately after rinsing.",
        "Do not use straight after toothpaste - it inactivates chlorhexidine. Separate the two, rinsing the mouth in between, or use them at different times of day. A course of about one month is what the label describes; staining of the teeth is temporary."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "Children under 12 years of age should not use the product unless recommended by a healthcare professional.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [
        {
          "trade_name": "ELUGEL ORAL GEL 20 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > PIERRE  FRANCE",
          "price_egp": 6.5,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 20000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "RECARE ORAL GEL 30 GM",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UNIPHARMA CO. > UNIPHARMA",
          "price_egp": 14.95,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 30000.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        }
      ],
      "condition_id": "aphthous-stomatitis"
    }
  ]
}