{ "schema_version": 1, "kind": "condition", "id": "anorectal-pain", "name": "Rectal or anal pain", "category": "acute", "sources": "Egyptian National Drug Formulary - git.pdf, Lactulose monograph (chapter PDF p119)", "review_status": "reviewed", "verified_against": "Egyptian National Drug Formulary - git.pdf, Lactulose monograph (chapter PDF p119)", "verified_date": "2026-08", "treatments": [ { "id": 200, "generic": "Lactulose", "line": 1, "is_adjunct": false, "form": "oral.liquid", "strength_mg": null, "adult_dose": "Starting dose 10-30 g/day (15-45 mL/day of oral solution); maintenance dose 10-20 g/day (15-30 mL/day)", "adult_duration": "As directed, titrated to comfortable soft stools", "dose_source": "Egyptian National Drug Formulary - git.pdf, Lactulose monograph (chapter PDF p119)", "rationale": "Stool softener/osmotic laxative to reduce straining and pain on defecation while an underlying cause (fissure, haemorrhoids, spasm) is examined for and treated.", "cautions": [ "Not a treatment for the underlying cause of anal pain (fissure, haemorrhoids, abscess, malignancy) - it only softens stool to reduce pain on defecation; the cause still needs to be examined for.", "Can cause bloating and flatulence, especially at the start of treatment.", "Refer urgently for rectal bleeding, a palpable mass, unexplained weight loss, fever, or pain not responding to conservative treatment." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "For constipation: children 7-14 years, 10 g (15 mL) starting, 7-10 g (10-15 mL) maintenance; children 1-6 years, 3-7 g (5-10 mL); infants under 1 year, 3 g (up to 5 mL).", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "Under 1 year", "age_min_months": 0, "age_max_months": 11, "dose_text": "3 g (up to 5 mL) daily" }, { "label": "1 to 6 years", "age_min_months": 12, "age_max_months": 83, "dose_text": "3 to 7 g (5 to 10 mL) daily" }, { "label": "7 to 14 years", "age_min_months": 84, "age_max_months": 179, "dose_text": "10 g (15 mL) to start, then 7 to 10 g (10 to 15 mL)" } ], "peds_doses": null, "brands": [ { "trade_name": "FARCOLAC 667GM/L SYRUP 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 7.5, "pack_count": null, "unit_price": null, "strength_mg": 667000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LACTOLINE 50% SYRUP 200ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALEXANDRIA", "price_egp": 9.25, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LAEVOLAC 67GM/100ML SYRUP 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA > FRESENIUS KABI", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": 67000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEDALAC 3.35GM/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 20.0, "pack_count": null, "unit_price": null, "strength_mg": 3350.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LAXOLAC 3.35GM/5ML SYRUP 300ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 40.0, "pack_count": null, "unit_price": null, "strength_mg": 3350.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LAXOLAC 3.35GM/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 50.0, "pack_count": null, "unit_price": null, "strength_mg": 3350.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "DUPHALAC 667GM/L SYRUP 200ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ABBOTT LABORATORIES", "price_egp": 143.0, "pack_count": null, "unit_price": null, "strength_mg": 667000.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LACTULOSE-AUG PHARMA 3.35GM/5ML SYRUP 320ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AUG PHARMA", "price_egp": 170.0, "pack_count": null, "unit_price": null, "strength_mg": 3350.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "VILLAPURG 67% SYRUP 120 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ESRAA PHARMACEUTICAL OPTIMA", "price_egp": 12.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "VILLAPURG 67% SYRUP 200 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ESRAA PHARMACEUTICAL OPTIMA", "price_egp": 17.75, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "anorectal-pain" } ] }