{ "schema_version": 1, "kind": "condition", "id": "allergic-rhinitis", "name": "Allergic rhinitis", "category": "chronic", "sources": "ARIA Guidelines 2020 · Egyptian National Drug Formulary - Respiratory Medicines 2026 (fexofenadine monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (chlorpheniramine maleate monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (xylometazoline monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (montelukast monograph)", "review_status": "reviewed", "verified_against": "ARIA Guidelines 2020 · Egyptian National Drug Formulary - Respiratory Medicines 2026 (fexofenadine monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (chlorpheniramine maleate monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (xylometazoline monograph) · Egyptian National Drug Formulary - Respiratory Medicines 2026 (montelukast monograph)", "verified_date": "2026-08", "treatments": [ { "id": 133, "generic": "Cetirizine", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "10 mg once daily", "adult_duration": "as-needed", "dose_source": "ARIA Guidelines 2020", "rationale": "Second-generation antihistamine that blocks the histamine driving sneezing, itching, and rhinorrhea, with little sedation; a standard first-line oral option for allergic rhinitis.", "cautions": [ "Cetirizine is a second-gen H1 blocker; the sedation risk is low but mild drowsiness is possible.", "Avoid alcohol.", "A dose reduction is required in renal impairment. Egyptian National Drug Formulary - Respiratory 2026, cetirizine monograph, renal dosage table: eGFR 30-49 mL/min 5 mg once daily; eGFR <30 not requiring dialysis 5 mg once every 2 days." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "2.5 mg daily (1-2 yrs), 5 mg daily (2-6 yrs), 10 mg daily over 6 yrs", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "1 to 2 years", "age_min_months": 12, "age_max_months": 23, "dose_text": "2.5 mg once daily" }, { "label": "2 to 6 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "5 mg once daily" }, { "label": "Over 6 years", "age_min_months": 72, "age_max_months": 216, "dose_text": "10 mg once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "EPIRIZINE 10 MG 10 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 15.5, "pack_count": 10, "unit_price": 1.55, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRITIN 10MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL NILE.", "price_egp": 42.0, "pack_count": 20, "unit_price": 2.1, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TOMAZINE 10MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ALFACURE PHARMACEUTICALS", "price_egp": 63.0, "pack_count": 30, "unit_price": 2.1, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRAK 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "PHARCO", "price_egp": 68.0, "pack_count": 20, "unit_price": 3.4, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HISTAZINE-1 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMRIYA", "price_egp": 68.0, "pack_count": 20, "unit_price": 3.4, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ZYRTEC 10 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 100.0, "pack_count": 20, "unit_price": 5.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CETRICHEW 10MG 20 CHEWABLE F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AL ROWAD PHARMACEUTICAL INDUSTRIAL CO.", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "HISTA CHEW 10 MG 20 CHEWABLE TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB CAPS > ADVOCURE", "price_egp": 15.0, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LERGFREE 5MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "DEBEIKY", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "EPIRIZINE 5MG/ML SYRUP 60 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO", "price_egp": 19.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 134, "generic": "Loratadine", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "10 mg once daily", "adult_duration": "as-needed", "dose_source": "ARIA Guidelines 2020", "rationale": "Non-sedating second-generation antihistamine, an alternative first-line oral option to cetirizine for allergic rhinitis symptoms.", "cautions": [ "Caution in severe hepatic impairment. Egyptian National Drug Formulary - Respiratory 2026, loratadine monograph, Hepatic impairment: \"Severe liver impairment - Adults and children weighing more than 30 kg: Initial: 10 mg every other day. Children weighing 30 kg or less: 5 mg every other day is recommended.\"", "Take on empty stomach or with meals.", "Loratadine is a non-sedating antihistamine." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "5 mg daily (2-5 yrs), 10 mg daily over 6 yrs", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to 5 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "5 mg once daily" }, { "label": "6 years and over", "age_min_months": 72, "age_max_months": 216, "dose_text": "10 mg once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "HISTALONG 10 MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS", "price_egp": 17.0, "pack_count": 20, "unit_price": 0.85, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "UNILORATADINE 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 17.0, "pack_count": 20, "unit_price": 0.85, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SEDCLARIT 10MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO", "price_egp": 19.5, "pack_count": 20, "unit_price": 0.97, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LORATADINE 10MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 25.5, "pack_count": 10, "unit_price": 2.55, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ONY 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA", "price_egp": 51.0, "pack_count": 20, "unit_price": 2.55, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALLERGETONE 10 MG 20 TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MARCYRL PHARMACEUTICAL INDUSTRIES (MPI) > SPLENDID PHARMA", "price_egp": 66.0, "pack_count": 20, "unit_price": 3.3, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CLARITINE 10MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SEDICO > BAYER HEALTHCARE", "price_egp": 110.0, "pack_count": 20, "unit_price": 5.5, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALLERGIRAZ 10MG 30 DISINTEGRATING TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "JEDCO INT. CO. FOR PHARMACEUTICALS > ELRAZY PHARMACEUTICALS-EGYPT", "price_egp": 31.5, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LORANO 5MG/5ML SYRUP 60ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MINA PHARM", "price_egp": 5.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "UNILORATADINE 5MG/5ML SYRUP 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "UNIPHARMA CO. > UNIPHARMA", "price_egp": 9.0, "pack_count": null, "unit_price": null, "strength_mg": 5.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 135, "generic": "Fluticasone propionate", "line": 1, "is_adjunct": false, "form": "nasal", "strength_mg": 0.05, "adult_dose": "2 sprays (100 mcg) into each nostril once daily", "adult_duration": "long-term", "dose_source": "ARIA Guidelines 2020", "rationale": "Intranasal corticosteroid that damps the local mucosal inflammation driving nasal congestion, sneezing, and rhinorrhea; first-line for moderate-to-severe allergic rhinitis, though full benefit takes a few days of regular use to appear.", "cautions": [ "First-line for moderate-severe symptoms; takes days for full benefit.", "Point nozzle slightly outward away from nasal septum.", "Local nasal irritation and minor nosebleeds are common." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "1 spray into each nostril once daily in children 4-11 years", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "4 to 11 years", "age_min_months": 48, "age_max_months": 143, "dose_text": "1 spray into each nostril once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "RHINORELIEF NASAL SUSP. 50 MCG/METERED SPRAY DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ARAB DRUG COMPANY (ADCO)", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIX NASAL SPRAY 50 MCG/METERED SPRAY DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EVA PHARMA", "price_egp": 76.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXONASE 50 MCG/METERED NASAL SPRAY 120 DOSE", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 133.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE DISKUS 50MCG/DOSE ACCUHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 36.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FLIXOTIDE EVOHALER 50MCG/ACTUATION INHALER", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 111.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 136, "generic": "Mometasone furoate", "line": 1, "is_adjunct": false, "form": "nasal", "strength_mg": 0.05, "adult_dose": "2 sprays (100 mcg) into each nostril once daily", "adult_duration": "long-term", "dose_source": "ARIA Guidelines 2020", "rationale": "Intranasal corticosteroid with high topical potency and minimal systemic absorption, an alternative to fluticasone for moderate-to-severe allergic rhinitis.", "cautions": [ "Direct away from septum.", "Discontinue if persistent nasal septum ulceration occurs.", "Mometasone furoate has high topical potency with minimal systemic bioavailability." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "1 spray into each nostril once daily in children 2-11 years", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to 11 years", "age_min_months": 24, "age_max_months": 143, "dose_text": "1 spray into each nostril once daily" } ], "peds_doses": null, "brands": [ { "trade_name": "SNIFFACAN 50MCG/G NASAL SPRAY 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SIGMA TEC", "price_egp": 25.2, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TABUNEX 50MCG/G NASAL SPRAY 120 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "TABUK PHARMACEUTICAL MANUFACTURING COMPANY > AL ANSAR FOR MARKETING", "price_egp": 28.8, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NORHINOSE 50MCG/DOSE NASAL SPRAY 120 DOSES", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND. > AMRIYA", "price_egp": 90.0, "pack_count": null, "unit_price": null, "strength_mg": 0.05, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 137, "generic": "Fexofenadine", "line": 1, "is_adjunct": false, "form": "oral.solid", "strength_mg": 120.0, "adult_dose": "120-180 mg once daily for seasonal allergic rhinitis, or 60 mg twice daily", "adult_duration": "as-needed", "dose_source": "Egyptian National Drug Formulary - Respiratory Medicines 2026 (fexofenadine monograph)", "rationale": "The Egyptian formulary licenses fexofenadine for allergic rhinitis from 2 years. It is the second-generation antihistamine with the least sedation of the three, which matters for a driver or a student, and it is a common Egyptian prescription.", "cautions": [ "Least sedating of the three oral antihistamines here.", "Reduce to 60 mg every 12 to 24 hours if eGFR is 10-50, and 60 mg every 24 hours below 10.", "Take the tablet with water, not with fruit juice, which reduces absorption. Allegra Allergy (fexofenadine hydrochloride) tablets, US OTC Drug Facts label (DailyMed SetID 81c1dcbb-28b3-4ad5-9f3d-9ccc16ddd173) says \"do not take with fruit juices\" and directs that the tablet be taken \"with water\".", "Antacids containing aluminium or magnesium reduce absorption; separate by 2 hours." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children 2-11 years: 30 mg (5 mL of the 30 mg/5 mL suspension) twice daily as required. From 12 years use the adult dose. Not established under 2 years for seasonal allergic rhinitis.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to under 12 years", "age_min_months": 24, "age_max_months": 143, "dose_text": "30 mg (5 mL of the 30 mg/5 mL suspension) twice daily as required" }, { "label": "12 years and over", "age_min_months": 144, "age_max_months": 216, "dose_text": "Use the adult dose" } ], "peds_doses": null, "brands": [ { "trade_name": "FEXOFENADINE-CID 120MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 12.0, "pack_count": 20, "unit_price": 0.6, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FEXODINE 120MG 10 CAP.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 8.0, "pack_count": 10, "unit_price": 0.8, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "SANZALERA 120 MG 14 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "FUTURE PHARMACEUTICAL INDUSTRIES (FPI) > TABUK PHARMA", "price_egp": 13.5, "pack_count": 14, "unit_price": 0.96, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALLERGYNA 120MG 10 F.C. TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLOBAL NAPI PHARMACEUTICALS > REXCEL", "price_egp": 15.0, "pack_count": 10, "unit_price": 1.5, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALLERFEN 120 MG 30 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "AMOUN", "price_egp": 96.0, "pack_count": 30, "unit_price": 3.2, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "FASTEL 120 MG 20 F.C.TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 66.0, "pack_count": 20, "unit_price": 3.3, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "TELFAST 120MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "SANOFI", "price_egp": 116.0, "pack_count": 20, "unit_price": 5.8, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ORGOFEXADINE 120MG 10 FILM COATED TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORGANOPHARMA > ORGANO", "price_egp": 5.5, "pack_count": null, "unit_price": null, "strength_mg": 120.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ALERTAM 30MG/5ML ORAL SUSP. 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MUP", "price_egp": 8.5, "pack_count": null, "unit_price": null, "strength_mg": 30.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "FEXODINE 30MG/5ML ORAL SUSP. 100 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 10.0, "pack_count": null, "unit_price": null, "strength_mg": 30.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 138, "generic": "Chlorpheniramine maleate", "line": 2, "is_adjunct": false, "form": "oral.solid", "strength_mg": 4.0, "adult_dose": "4 mg every 4-6 hours, maximum 24 mg in 24 hours", "adult_duration": "as-needed", "dose_source": "Egyptian National Drug Formulary - Respiratory Medicines 2026 (chlorpheniramine maleate monograph)", "rationale": "It is on the Egyptian EML 2025 under antiallergics and the Egyptian formulary names allergic/vasomotor rhinitis and hay fever as indications. It is cheap and everywhere in Egypt, and a patient who is already taking it needs to be able to find it - even though the sedation makes it second choice to the three above.", "cautions": [ "Sedation and somnolence are very common - over 10 percent. A second-generation antihistamine is the better first choice; keep this for the night dose or where cost decides.", "Contraindicated in acute asthma, in coma or pre-coma, in known brain damage or epilepsy, and within 14 days of an MAOI.", "In the elderly the anticholinergic effects bite harder - the formulary suggests capping at 12 mg in 24 hours.", "Anticholinergic load: dry mouth, blurred vision, urinary retention. Caution in prostatism and glaucoma." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "2-6 years: 1 mg every 4-6 hours, maximum 6 mg/day. 6 to under 12 years: 2 mg every 4-6 hours, maximum 12 mg/day. 12 years and over: 4 mg every 4-6 hours, maximum 24 mg/day. Not recommended under 2 years.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to under 6 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "1 mg every 4-6 hours, maximum 6 mg/day" }, { "label": "6 to under 12 years", "age_min_months": 72, "age_max_months": 143, "dose_text": "2 mg every 4-6 hours, maximum 12 mg/day" }, { "label": "12 years and over", "age_min_months": 144, "age_max_months": 216, "dose_text": "4 mg every 4-6 hours, maximum 24 mg/day" } ], "peds_doses": null, "brands": [ { "trade_name": "CHLORPHENIRAMINE 4 MG 20 TAB. B.P.93", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HI-PHARM > PYRAMIDS TRADING", "price_egp": 1.0, "pack_count": 20, "unit_price": 0.05, "strength_mg": 4.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "CHLORANTINE-M 4MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MISR", "price_egp": 1.4, "pack_count": 20, "unit_price": 0.07, "strength_mg": 4.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PIRAFENE 4MG 20 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 2.45, "pack_count": 20, "unit_price": 0.12, "strength_mg": 4.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ANALLERGE 4 MG 60 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 30.0, "pack_count": 60, "unit_price": 0.5, "strength_mg": 4.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "PIRAFENE 2MG/5ML SYRUP 120ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "MEMPHIS", "price_egp": 10.0, "pack_count": null, "unit_price": null, "strength_mg": 2.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null }, { "trade_name": "ANALLERGE 2MG/5ML SYRUP 100ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "KAHIRA", "price_egp": 24.0, "pack_count": null, "unit_price": null, "strength_mg": 2.0, "exact_strength": false, "exact_form": false, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 139, "generic": "Xylometazoline", "line": 2, "is_adjunct": true, "form": "nasal", "strength_mg": 0.1, "adult_dose": "1 spray (0.1%) into each nostril every 8 hours, maximum 3 sprays per nostril per day", "adult_duration": "no more than 7 consecutive days", "dose_source": "Egyptian National Drug Formulary - Respiratory Medicines 2026 (xylometazoline monograph)", "rationale": "The Egyptian formulary's indication for xylometazoline names perennial and allergic rhinitis (including hay fever) directly. Blockage is the symptom an antihistamine does least for, and this is what gets added when the nose will not open - it is already on the Egyptian EML under nasal decongestants.", "cautions": [ "Not more than 7 consecutive days - beyond that it causes rebound congestion and can atrophy the nasal mucosa. This is the single most important thing to say to the patient.", "Tell the patient to see you again if symptoms last beyond 3 days.", "Contraindicated in closed-angle glaucoma, rhinitis sicca, phaeochromocytoma and prostatic hypertrophy, and within 2 weeks of an MAOI.", "Caution in cardiovascular disease, diabetes and thyroid disorders.", "Should not be used in pregnancy - no adequate data, and it is a vasoconstrictor." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "Children 6-11 years: 1-2 drops of the 0.05% formulation in each nostril once or twice daily, maximum twice per nostril per day. The 0.1% formulation is contraindicated under 12 years and the 0.05% under 6 years.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "6 to 11 years", "age_min_months": 72, "age_max_months": 143, "dose_text": "1 to 2 drops of the 0.05% formulation in each nostril, once or twice daily - maximum twice per nostril per day. The 0.1% is contraindicated under 12 years." } ], "peds_doses": null, "brands": [ { "trade_name": "OTRIVIN 0.1% ADULT NASAL SPRAY 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "NOVARTIS > GLAXO SMITHKLINE", "price_egp": 32.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BALKIS 0.1% ADULT NASAL DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO > DOLORGIT", "price_egp": 3.75, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RHINEX 0.1% ADULT NASAL DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OTRIVIN 0.1% ADULT NASAL DROPS 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 24.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "BALKIS 0.05% INFANTILE NASAL DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EIPICO > DOLORGIT", "price_egp": 3.5, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "NASOSTOP 0.05% PAED NASAL DROPS 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HI-PHARM", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "RHINEX 0.05% INFANTILE NASAL DROPS 10 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "CID", "price_egp": 18.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OTRIVIN 0.05% PEDIATRIC NASAL DROPS 15 ML", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "GLAXO SMITHKLINE", "price_egp": 24.0, "pack_count": null, "unit_price": null, "strength_mg": null, "exact_strength": false, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" }, { "id": 140, "generic": "Montelukast", "line": 3, "is_adjunct": true, "form": "oral.solid", "strength_mg": 10.0, "adult_dose": "10 mg once daily in the evening", "adult_duration": "review at 2-4 weeks and stop if there is no response", "dose_source": "Egyptian National Drug Formulary - Respiratory Medicines 2026 (montelukast monograph)", "rationale": "The Egyptian formulary licenses montelukast for seasonal and perennial allergic rhinitis but tells you to reserve it for patients with an inadequate response or intolerance to alternative therapies, because of the neuropsychiatric risk. That is exactly a 'consider' - it belongs on the screen with the reservation attached, particularly for the patient who also has asthma.", "cautions": [ "Second line by the formulary's own wording - reserve it for inadequate response to or intolerance of an antihistamine and a nasal steroid.", "Neuropsychiatric reactions: agitation, sleep disturbance, depression, suicidal thinking. Warn the patient and the parent explicitly and tell them to stop and come back.", "Review at 2-4 weeks and discontinue if there is no clinical response - do not let it become a repeat prescription by default.", "It is not a rescue drug for an acute asthma attack; a patient with asthma still needs a short-acting beta agonist." ], "peds_mgkg_low": null, "peds_mgkg_high": null, "peds_max_mg": null, "peds_basis": null, "peds_unit": null, "peds_note": "6-14 years: one 5 mg chewable tablet daily. 2-5 years: one 4 mg chewable tablet or one 4 mg granule sachet daily. Perennial allergic rhinitis is licensed from 6 months, seasonal from 2 years. A child with both asthma and allergic rhinitis takes one dose only, in the evening.", "peds_min_weight_kg": null, "peds_max_weight_kg": null, "peds_age_min_months": null, "peds_age_max_months": null, "peds_age_bands": [ { "label": "2 to 5 years", "age_min_months": 24, "age_max_months": 71, "dose_text": "One 4 mg chewable tablet or one 4 mg granule sachet daily" }, { "label": "6 to 14 years", "age_min_months": 72, "age_max_months": 179, "dose_text": "One 5 mg chewable tablet daily" } ], "peds_doses": null, "brands": [ { "trade_name": "PIRONTAGONIST 10MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > ADVANCE PHARMA", "price_egp": 60.0, "pack_count": 20, "unit_price": 3.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "ASMALAIR 10MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "HI-PHARM", "price_egp": 40.0, "pack_count": 10, "unit_price": 4.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MONTEKAL 10MG 10 TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EUROPEAN EGYPTIAN PHARM. IND.", "price_egp": 40.0, "pack_count": 10, "unit_price": 4.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "INLETAIR 10 MG 10 F.C.TAB.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ORGANOPHARMA", "price_egp": 47.0, "pack_count": 10, "unit_price": 4.7, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "MONTELOSAB 10 MG 14 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "P&C > VERCURE", "price_egp": 82.0, "pack_count": 14, "unit_price": 5.86, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "LELIPEL 10 MG 20 F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EGPI > GLOBE INTERNATIONAL PHARMACEUTICALS", "price_egp": 120.0, "pack_count": 20, "unit_price": 6.0, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "OPIKAST 10 MG 14 SCORED F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "EL-OBOUR", "price_egp": 22.2, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null }, { "trade_name": "STATUKAST 10 MG 10 SCORED F.C. TABS.", "scientific_name": null, "normalized_ingredient": null, "manufacturer": "ADWIA", "price_egp": 41.5, "pack_count": null, "unit_price": null, "strength_mg": 10.0, "exact_strength": true, "exact_form": true, "discontinued": false, "also_contains": null } ], "condition_id": "allergic-rhinitis" } ] }