{
  "schema_version": 1,
  "kind": "condition",
  "id": "acute-bronchiolitis",
  "name": "Acute Bronchiolitis",
  "category": "infectious",
  "sources": "MSF Essential Drugs 2024 - paracetamol (oral) · No dose - supportive care, no medicine given · Erickson EN, Bhakta RT, Tristram D, Mendez MD. Pediatric Bronchiolitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Last Update: January 12, 2025. · AAP Clinical Practice Guideline: Bronchiolitis 2014 · NICE Guideline NG9: Bronchiolitis in children 2021",
  "review_status": "reviewed",
  "verified_against": "MSF Essential Drugs 2024 - paracetamol (oral) · No dose - supportive care, no medicine given · Pediatric Bronchiolitis - disease-level clinical article (bronchiolitis-infantile-clinical.txt)",
  "verified_date": "2026-08",
  "treatments": [
    {
      "id": 35,
      "generic": "No drug therapy in primary care (Supportive care)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": "Bronchiolitis is a disease of infants, usually under 12 months. There is no effective drug treatment: management is small frequent feeds, nasal saline and suction if feeding is blocked, and watching the work of breathing.",
      "adult_duration": "Supportive, through the illness",
      "dose_source": "No dose - supportive care, no medicine given",
      "rationale": "Supportive care is the mainstay - hydration, feeding, nasal suctioning, and oxygen for hypoxaemia - alongside recognising the infant who is tiring. Steroids are not recommended, and antibiotics are reserved for clear evidence of a superimposed infection. Bronchodilators are not universally effective, though a trial of aerosolised salbutamol may be considered for an infant with severe respiratory compromise.",
      "cautions": [
        "A DISEASE OF INFANTS - it does not occur in adults, so no adult regimen applies.",
        "Inhaled or oral steroids do not alter the course, and antibiotics are only for clear evidence of a superimposed infection. Bronchodilators are not universally effective, but a trial of aerosolised salbutamol may be considered, especially for an infant with severe respiratory compromise.",
        "Admit if feeding falls below roughly half of normal intake.",
        "RED FLAG - Apnoea episodes, marked respiratory distress with grunting, severe recession or nasal flaring, or poor feeding or dehydration."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": "This IS the paediatric entry - the condition does not occur in adults. Admit if feeding drops below about half of normal, or if there is apnoea, grunting, marked recession or cyanosis.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "acute-bronchiolitis"
    },
    {
      "id": 37,
      "generic": "Referral & safety-netting (no drug therapy)",
      "line": 1,
      "is_adjunct": false,
      "form": null,
      "strength_mg": null,
      "adult_dose": null,
      "adult_duration": null,
      "dose_source": "Pediatric Bronchiolitis - disease-level clinical article (bronchiolitis-infantile-clinical.txt)",
      "rationale": "Carries the referral criteria and warning signs for this condition, which apply whichever treatment is chosen.",
      "cautions": [
        "RED FLAG - The criteria for hospitalization and supplemental oxygen are tachypnea >60 breaths/min, SpO2 <92%, or inability to feed."
      ],
      "peds_mgkg_low": null,
      "peds_mgkg_high": null,
      "peds_max_mg": null,
      "peds_basis": null,
      "peds_unit": null,
      "peds_note": null,
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": null,
      "brands": [],
      "condition_id": "acute-bronchiolitis"
    },
    {
      "id": 36,
      "generic": "Paracetamol",
      "line": 2,
      "is_adjunct": true,
      "form": "oral.solid",
      "strength_mg": 500.0,
      "adult_dose": "For fever or discomfort in the infant, dosed by weight - see the paediatric calculation. Bronchiolitis does not occur in adults, so the adult column does not apply here.",
      "adult_duration": "As needed for pain or fever",
      "dose_source": "MSF Essential Drugs 2024 - paracetamol (oral)",
      "rationale": "Symptomatic relief of the pain and fever only. It does not treat the cause, and the dose is the same whatever the cause is.",
      "cautions": [
        "Dose the INFANT by weight - the adult figure carried on other screens is not the dose here.",
        "Relief only - it does not treat what is causing the pain or fever.",
        "Check every other product the patient is taking for paracetamol; combination cold and flu preparations are the usual route to an accidental overdose.",
        "Reduce the dose in significant liver disease, chronic alcohol use, or low body weight.",
        "RED FLAG - Admit or refer the infant for apnoea episodes, marked respiratory distress with grunting, severe chest retraction or nasal flaring, poor feeding or dehydration, or low oxygen saturation or a bluish colour. A very young infant, or one with underlying heart or lung disease or prematurity, warrants a lower threshold for admission."
      ],
      "peds_mgkg_low": 15.0,
      "peds_mgkg_high": 15.0,
      "peds_max_mg": 500.0,
      "peds_basis": "dose",
      "peds_unit": "mg",
      "peds_note": "Child 1 month and over: 15 mg/kg per dose, 3 or 4 times daily, maximum 60 mg/kg daily. Child under 1 month: 10 mg/kg per dose, 3 or 4 times daily, maximum 40 mg/kg daily. MSF's own weight table gives one 500 mg tablet three times daily from 30 kg to under 50 kg, so 500 mg is the per-dose ceiling; the 60 mg/kg daily total still applies.",
      "peds_min_weight_kg": null,
      "peds_max_weight_kg": null,
      "peds_age_min_months": null,
      "peds_age_max_months": null,
      "peds_age_bands": null,
      "peds_doses": [
        {
          "weight_kg": 10,
          "low_mg": 150,
          "high_mg": 150,
          "capped": false
        },
        {
          "weight_kg": 20,
          "low_mg": 300,
          "high_mg": 300,
          "capped": false
        },
        {
          "weight_kg": 30,
          "low_mg": 450,
          "high_mg": 450,
          "capped": false
        },
        {
          "weight_kg": 40,
          "low_mg": 500,
          "high_mg": 500,
          "capped": true
        }
      ],
      "brands": [
        {
          "trade_name": "FEBRIMOL 500 MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 3.5,
          "pack_count": 20,
          "unit_price": 0.17,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CETAMOL 500 MG 20 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MEMPHIS",
          "price_egp": 8.0,
          "pack_count": 20,
          "unit_price": 0.4,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PARACETAMOL-MUP 500MG B.P. 20 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MUP",
          "price_egp": 13.0,
          "pack_count": 20,
          "unit_price": 0.65,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "CETAL 500 MG 20 TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "EIPICO",
          "price_egp": 24.0,
          "pack_count": 20,
          "unit_price": 1.2,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ARKADOLOW 500 MG 30 F.C. TABS.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "UTOPIA",
          "price_egp": 42.0,
          "pack_count": 30,
          "unit_price": 1.4,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "PARAMOL 500MG 20 TAB.",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "MISR",
          "price_egp": 38.0,
          "pack_count": 20,
          "unit_price": 1.9,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "ADOL 500MG 24 CAPLETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "JULPHAR",
          "price_egp": 32.0,
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          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "AUGICETAMIDE 500 MG 20 SACHETS",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "AUG PHARMA",
          "price_egp": 50.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": 500.0,
          "exact_strength": true,
          "exact_form": true,
          "discontinued": false,
          "also_contains": null
        },
        {
          "trade_name": "FEBRIMOL ORAL DROPS 20 ML",
          "scientific_name": null,
          "normalized_ingredient": null,
          "manufacturer": "PHARCO",
          "price_egp": 4.0,
          "pack_count": null,
          "unit_price": null,
          "strength_mg": null,
          "exact_strength": false,
          "exact_form": false,
          "discontinued": false,
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        },
        {
          "trade_name": "THERA-LO 3.2G/100ML ORAL SUSP. 100 ML",
          "scientific_name": null,
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          "manufacturer": "PHAROPHARMA",
          "price_egp": 5.0,
          "pack_count": null,
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          "strength_mg": 3200.0,
          "exact_strength": false,
          "exact_form": false,
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        }
      ],
      "condition_id": "acute-bronchiolitis"
    }
  ]
}